Patents by Inventor Thomas Vazquez

Thomas Vazquez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INTERLEUKIN 2 CHIMERIC CONSTRUCTS WITH TARGETING SPECIFICY TO INFLAMED TISSUES
    Publication number: 20240376172
    Abstract: The present invention relates to a targeted chimeric construct, comprising i) an interleukin 2 (IL2) moiety and ii) a targeting moiety which binds to an oxidized protein or oxidized lipid. The targeting moiety is preferably an antibody or scFv binding specific oxidized proteins or oxidized lipids and targets the fusion protein to inflammatory tissues. The chimeric construct preferably further comprises a beta chain of the C4b-binding protein (C4BP), which is capable of forming a dimeric protein.
    Type: Application
    Filed: October 6, 2022
    Publication date: November 14, 2024
    Inventors: David KLATZMANN, Alain TEDGUI, Thomas VAZQUEZ, Nicolas BILLIALD
  • INTERLEUKIN 2 CHIMERIC CONSTRUCTS
    Publication number: 20230036793
    Abstract: The present invention relates to a chimeric construct, comprising i) an interleukin 2 (IL2) moiety and ii) a beta chain of the C4b-binding protein (C4BP?) or at least one fragment or functional variant thereof that is capable of forming a dimeric protein.
    Type: Application
    Filed: December 11, 2020
    Publication date: February 2, 2023
    Inventors: David KLATZMANN, Nicolas BILLIALD, Thomas VAZQUEZ, Jérémie MARIAU
  • COMBINATION OF INTERLEUKIN-2 WITH AN INTERLEUKIN 1 INHIBITOR, CONJUGATES AND THERAPEUTIC USES THEREOF
    Publication number: 20210236599
    Abstract: The present invention relates to a combination of i) interleukin-2 (IL-2) and ii) an interleukin 1 (IL-1) inhibitor, for use in treating an auto-immune and/or inflammatory disorder in a subject. It is also provided a pharmaceutical composition comprising interleukin-2 (IL-2) and an interleukin-1 (IL-1) inhibitor. The invention further provides a conjugate comprising IL-2 conjugated to an IL-1 inhibitor.
    Type: Application
    Filed: August 13, 2019
    Publication date: August 5, 2021
    Inventors: David Klatzmann, Jérémie Mariau, Paul-Gydéon Ritvo, Encarnita Mariotti-Ferrandiz, Thomas Vazquez, Nicolas Billiald
  • Bottle or similar article
    Patent number: D300208
    Type: Grant
    Filed: December 30, 1985
    Date of Patent: March 14, 1989
    Assignee: Armor All Products Corporation
    Inventors: Thomas Vazquez, John D. Ferguson