Abstract: Methods for treating breast cancer involving the administration of a compound that selectively inhibits pathological production of human vascular endothelial growth factor (VEGF) are described. The compound can be administered as a single agent therapy or in combination with one or more additional therapies to a human in need of such treatment.

Abstract: Compounds that selectively inhibit pathological production of human vascular endothelial growth factor (VEGF) and compositions comprising such Compounds are described. Compounds that inhibit viral replication or the production of viral RNA or DNA or viral protein and compositions comprising such Compounds are described. Also described are methods of reducing VEGF using such Compounds and methods for treating cancer and non-neoplastic conditions involving the administration of such Compounds. Further described are methods of inhibiting viral replication or the production of viral RNA or DNA or viral protein using such Compounds and methods for treating viral infections involving the administration of such Compounds. The Compounds may be administered as a single agent therapy or in combination with one or more additional therapies to a human in need of such treatments.

Abstract: Methods for treating prostate cancer involving the administration of a compound that selectively inhibits pathological production of human vascular endothelial growth factor (VEGF) are described. Methods for treating benign prostatic hyperplasia involving the administration of a compound that selectively inhibits pathological production of human VEGF are also described. The compound may be administered as a single-agent therapy or in combination with one or more additional therapies to a human in need of such treatment.

Abstract: Methods for treating Kaposi's sarcoma involving the administration of a compound that selectively inhibits pathological production of human VEGF are described. The compound can be administered as a single-agent therapy or in combination with one or more additional therapies to a human in need of such treatment.

Abstract: Methods for treating neurofibromatosis involving the administration of a compound that selectively inhibits pathological production of human VEGF are described. The compound can be administered as a single-agent therapy or in combination with one or more additional therapies to a human in need of such treatment.

Abstract: Methods for treating brain tumors involving the administration of a compound that selectively inhibits pathological production of human VEGF are described. The compound can be administered as a single agent therapy or in combination with one or more additional therapies to a human in need of such treatment.

Abstract: In accordance with the present invention, methods for inhibiting the translation of VEGF and methods for decreasing VEGF level by inhibiting VEGF translation are provided. In another aspect of the invention, compounds that inhibit the 5?-UTR-dependent translation of VEGF and methods for identifying such compounds are provided.

Abstract: An upper body elevator includes a generally wedge-shaped elevator body comprising a lower elevator pillow comprising a first plurality of adjacent air tubes and an upper elevator pillow comprising a second plurality of adjacent air tubes carried by the lower elevator pillow.

Abstract: This lounging device is an upper body elevator apparatus having an optional neck rest that should be used for recreational and/or therapeutic purposes. With an elevation of almost 90° the elongated tubular pillows are between a top and bottom sheet and are connected by gussets which gives the device its wedge effect. On either side of the center surface are air diffusers which allow air to diffuse from the pillows (pneumatic cushions) of the center surface to comfort and support the back. The elevating wedge and optional tubular neck support operate together to elevate the head at an angle comfortable for sitting in an upright position for many recreational and therapeutic purposes. An elongated tubular anchor/butt rest is shown connected to bottom sheet to include a lower body support surface. This is a cost effective device that every household can afford. Other embodiments are described and shown.

Abstract: A fireproofing method for structural building construction members is disclosed. The method includes encasing a portion of each building construction member with autoclaved aerated concrete (AAC) elements profiled to surround exterior profiles of the portion of the each building construction member.

Abstract: A system for cleaning litter in a poultry house by removing caked litter while leaving uncaked litter. The system comprises a separator that connects and disconnects to the front bucket of a skid-steer loader while the operator remains seated. The separator and bucket couple via a bucket and separator coupling. One coupling comprises two spaced apart parallel arms that insert into corresponding sleeves that form the other coupling. Connecting requires aligned forward loader movement with the separator on the ground while disconnecting requires reverse loader movement. The separator comprises a chassis supporting a blade that forces litter into the separator. A plurality of spikes on a rotating reel forcefully break the entering litter into smaller pieces as an integral ramp feeds the litter onto an upwardly moving conveyor.

Abstract: A method and apparatus for cooling the heat generated by a gas turbine engine mounted in a compartment is provided. The apparatus comprises a novel eductor that incorporates a mixer nozzle to entrain sufficient air flow through the compartment to provide all the necessary cooling. The engine's oil cooler is mounted to the eductor so that the entrained air flow passes through it and cools the engine's oil. The novel eductor also has means for receiving a flow of high velocity air from the engine and injecting this air downstream of the mixer nozzle to enhance the entraining of the cooling flow.

Abstract: The invention provides a fluid power demonstration facility comprising means defining a fluid power source, directing means in fluid communication with the fluid power source and for selectively supplying fluid power from the fluid power source, pre-arranged rotary means, in fluid communication with the directing means, for demonstrating rotational motion produced in response to fluid power, and adapted to be selectively engageable by the directing means, and pre-arranged linear means, in fluid communication with the directing means, for demonstrating linear motion produced in response to fluid power, selectively engageable by the control means, and separate from the means for demonstrating rotational motion.