Abstract: A group of known compounds has been found to have polymerase inhibitor qualities and are presumed to be efficacious in the protection of human cells from damage by the SARS-CoV-2 virus, which causes the COVID-19 disease. These compounds, referred to herein as Special Phenyl Compounds, provide such protection by inhibiting replication of the virus, which is done by interfering with its RNA transcription process. These compounds can also be used to treat diseases caused by structurally related viruses such as West Nile virus, Marburg virus, Ebola virus, dengue virus, HIV, hepatitis C virus (HepC), and coronaviruses other than SARS-CoV2. Patients are treated by administering effective doses of one or more of the compounds.

Abstract: Certain compounds of formula I: I and salts including pharmaceutically acceptable salts thereof are disclosed. Also disclosed are pharmaceutical compositions comprising a compound of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I and therapeutic methods using a compound of formula I.

Abstract: Certain compounds of formula I: I and salts including pharmaceutically acceptable salts thereof are disclosed. Also disclosed are pharmaceutical compositions comprising a compound of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I and therapeutic methods using a compound of formula I.