Abstract: According to the invention there is provided a controlled environment production facility, including: a climate controlled growing chamber, and an absorption chiller. The climate controlled growing chamber includes artificial lighting and at least one cooling and dehumidification unit. The cooling and dehumidification unit is supplied with chilled water from the absorption chiller.

Abstract: Implantable devices having rougher surfaces and more surface area can be made of polymers such as PEEK or PAEK using a 3D printing process. The 3D implantable devices can be soaked in a lipase solution to etch the surface which can alter the surface energy, surface roughness, and atomic composition. After the lipase solution soaking, the 3D printed implantable devices can be removed from the solution and thoroughly rinsed with a cleaning fluid such as an acetone solution. The outer surfaces of the lipase treated 3D printed implantable device can also be surface activated by UV light or other photocatalytic activity to decrease bacteria attachment and growth. The surface energy of the resulting 3D printed implantable devices enhances patient ingrowth resulting in a faster recovery.

Abstract: Methods of reducing or inhibiting growth of microbes (viruses, fungi and/or bacteria, including multi-drug resistant bacteria) can be carried out by applying a formulation including porphyrin nanoparticles to a surface to impart a residue of the porphyrin nanoparticles on the surface. The applied porphyrin nanoparticles residue can reduce or inhibit growth of infectious microbes on the surface for an extended period of time such as for at least 24 hours, 2 days, one week, etc. The applied porphyrin nanoparticles have high antimicrobial activity under visible light and without visible light.

Abstract: Embodiments disclosed herein generally relate to systems and methods for communicating data with a tone-emitting device. A system for communicating an inaudible tone includes a tone-emitting device. The tone-emitting device includes a tone-emitting speaker for emitting an inaudible tone and a tone-determining computing device communicatively coupled to the tone-emitting speaker. The tone-determining computing device includes a non-transitory computer-readable medium that stores logic that, when executed by the tone-determining computing device, causes the tone-determining computing device to receive data related to a characteristic of an object, encode an inaudible tone that represents at least a portion of the data and send instructions to the tone-emitting speaker for outputting the inaudible tone.

Abstract: According to the invention there is provided a controlled environment production facility, including a climate controlled growing chamber, and an absorption chiller. The climate controlled growing chamber includes artificial lighting and at least one cooling and dehumidification unit. The cooling and dehumidification unit is supplied with chilled water from the absorption chiller.

Abstract: A continuous perfusion bioreactor for microbial synthesis of metallic nanoparticles provides synthesis of nanoparticles without washout of the microbial cells. The perfusion bioreactor includes an inlet fluidically coupled to a holding compartment with a first flow barrier, which disperses the medium into a reaction compartment suitable for culture of microbial cells which synthesize nanoparticles. A second flow barrier in the reaction compartment prevents washout of the microbial cells but enables collection of the nanoparticles suspended in depleted nutrient medium.

Abstract: Methods for treating coronavirus infection, such as an infection caused by SARS-CoV-2, in a subject in need thereof include administering to the subject a therapeutically effective amount of a composition comprising an isolated polypeptide targeting the spike protein and the transmembrane region of the coronavirus envelope protein. Compositions include isolated polypeptides complementary to residues 30-38 of the envelope protein transmembrane region.

Abstract: A method of utilizing tones includes receiving content including at least an audio portion for broadcast to a first plurality of users having a first recipient computing device and a second plurality of users having a second recipient computing device, receiving data comprising a first and a second message, determining one or more locations within the content for embedding the first and second messages, converting at least the first and second messages into a plurality of tones that cannot be directly detected by the first and second pluralities of users during broadcast, incorporating the plurality of tones into the content at the one or more locations, and providing the content with the plurality of tones for broadcast via a presentation device such that the plurality of tones are detected by the first and second recipient devices for determining at least one of the first and second messages.

Abstract: An on-demand drug release system provides an implantable drug delivery platform including a drug embedded in a controllable drug release structure. The drug release structure binds or compartmentalizes the drug until release of the drug is initiated by absorption of a near infrared release signal provided by a health care professional. The system allows more effective therapeutic use of opioids and other drugs, and prevents their abuse.

Abstract: Embodiments provided herein include systems and methods for providing a tone-based kiosk service. One embodiment of a tone-based kiosk includes a display, a processor, and a memory component. The memory component may be configured to store logic that, when executed by the processor, causes the tone-based kiosk to establish an encrypted connection with the mobile device and broadcast a first tone that includes first encrypted data for rendering a user interface at the mobile device, wherein the first encrypted data includes information related to offerings by the establishment. In some embodiments, the logic causes the tone-based kiosk to provide at least a portion of the user interface for display, receive a second tone that includes second encrypted data that includes instructions navigating the user interface via the mobile phone to create order details for an order, and receive an indication that the order is complete.

Abstract: Embodiments provided herein include systems and methods for providing a tone-based service. Some embodiments include receiving reservation data for a patron at an establishment and receiving a first tone from a first mobile device of the patron. The first tone may be non-naturally occurring and human imperceptible, where the first tone includes data that identifies the patron and the reservation. These embodiments may further include determining whether the reservation includes at least one other patron, determining whether a second tone has been received from a second mobile device associated with the at least one other patron indicating the at least one other patron is present at the establishment. In response to determining that the at least one other patron is not present at the establishment, embodiments include providing a message to the patron that other members of the reservation have not yet arrived.

Abstract: A method of utilizing tones includes receiving content including at least an audio portion for broadcast to a first plurality of users having a first recipient computing device and a second plurality of users having a second recipient computing device, receiving data comprising a first and a second message, determining one or more locations within the content for embedding the first and second messages, converting at least the first and second messages into a plurality of tones that cannot be directly detected by the first and second pluralities of users during broadcast, incorporating the plurality of tones into the content at the one or more locations, and providing the content with the plurality of tones for broadcast via a presentation device such that the plurality of tones are detected by the first and second recipient devices for determining at least one of the first and second messages.

Abstract: A method of utilizing tones includes receiving content including at least an audio portion for broadcast to a first plurality of users having a first recipient computing device and a second plurality of users having a second recipient computing device, receiving data comprising a first and a second message, determining one or more locations within the content for embedding the first and second messages, converting at least the first and second messages into a plurality of tones that cannot be directly detected by the first and second pluralities of users during broadcast, incorporating the plurality of tones into the content at the one or more locations, and providing the content with the plurality of tones for broadcast via a presentation device such that the plurality of tones are detected by the first and second recipient devices for determining at least one of the first and second messages.

Abstract: Systems and methods for utilizing tones are disclosed. A method of receiving tones may include receiving content for broadcast to a recipient computing device, receiving data for including with the content, where the data includes an instruction for the recipient computing device to perform in response to detecting the data, and converting the data into an inaudible tone for inclusion with the content. The method may also include determining a location within the content to include the inaudible tone, incorporating the inaudible tone into the content at the location, such that the inaudible tone and the content and broadcast to the recipient computing device, and providing the inaudible tone and content for broadcast.

Abstract: A method of utilizing tones includes receiving content including at least an audio portion for broadcast to a first plurality of users having a first recipient computing device and a second plurality of users having a second recipient computing device, receiving data comprising a first and a second message, determining one or more locations within the content for embedding the first and second messages, converting at least the first and second messages into a plurality of tones that cannot be directly detected by the first and second pluralities of users during broadcast, incorporating the plurality of tones into the content at the one or more locations, and providing the content with the plurality of tones for broadcast via a presentation device such that the plurality of tones are detected by the first and second recipient devices for determining at least one of the first and second messages.

Abstract: Embodiments disclosed herein generally relate to systems and methods for communicating data with a tone-emitting device. A system for communicating an inaudible tone includes a tone-emitting device. The tone-emitting device includes a tone-emitting speaker for emitting an inaudible tone and a tone-determining computing device communicatively coupled to the tone-emitting speaker. The tone-determining computing device includes a non-transitory computer-readable medium that stores logic that, when executed by the tone-determining computing device, causes the tone-determining computing device to receive data related to a characteristic of an object, encode an inaudible tone that represents at least a portion of the data and send instructions to the tone-emitting speaker for outputting the inaudible tone.

Abstract: Provided are polymersomes for co-delivery of hydrophobic metallic nanoparticles and pharmaceutical agents and suspensions of such polymersomes. Also provided are methods of making such polymersomes and suspensions of polymersome and methods of using the same to treat diseases or conditions.

Abstract: Systems and methods for utilizing tones are disclosed. A method of receiving tones may include receiving content for broadcast to a recipient computing device, receiving data for including with the content, where the data includes an instruction for the recipient computing device to perform in response to detecting the data, and converting the data into an inaudible tone for inclusion with the content. The method may also include determining a location within the content to include the inaudible tone, incorporating the inaudible tone into the content at the location, such that the inaudible tone and the content and broadcast to the recipient computing device, and providing the inaudible tone and content for broadcast.

Abstract: Provided are polymersomes for co-delivery of hydrophobic metallic nanoparticles and pharmaceutical agents and suspensions of such polymersomes. Also provided are methods of making such polymersomes and suspensions of polymersome and methods of using the same to treat diseases or conditions.

Abstract: The present invention generally relates to work platforms, and, more particularly, to a work platform for use with a lift truck to elevate personnel safely and conveniently.