Patents by Inventor Thomas Weindl

Thomas Weindl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hemostatic Materials Based on Aldehyde-Functional Polysaccharides
    Publication number: 20250032666
    Abstract: The present invention is directed to hemostatic and/or tissue adhesive formulations comprising crosslinked polysaccharide particles that have been oxidized to generate aldehyde- and carboxylic functional moieties therein, and wherein said formulations further contain a buffer that maintains a slightly alkaline environment. These formulations can be applied onto tissue in the form of a powder, paste or patch to effect hemostasis or sealing.
    Type: Application
    Filed: July 25, 2023
    Publication date: January 30, 2025
    Inventors: Thomas Weindl, Benjamin Fitz, Gaojie Hu
  • Highly elastic medical sealants for flexible soft tissue
    Patent number: 12168081
    Abstract: Provided herein are compositions, systems and surgical methods for treating expandable soft tissue utilizing a reactive liquid hydrogel sealant mixture including a cross-linkable electrophilic compound, a nucleophilic compound, and an amphiphilic poly(alkyl)ene glycol block polymer in an amount of 20% (w/v) or less of the sealant composition. The composition can optionally include a viscosifier, in an amount of 0.1% to 1.0% (w/v) of the sealant composition.
    Type: Grant
    Filed: May 6, 2022
    Date of Patent: December 17, 2024
    Assignee: Ethicon, Inc.
    Inventors: Sai Veruva, Salim Ghodbane, Thomas Weindl
  • Highly Elastic Medical Sealants for Flexible Soft Tissue
    Publication number: 20230355831
    Abstract: Provided herein are compositions, systems and surgical methods for treating expandable soft tissue utilizing a reactive liquid hydrogel sealant mixture including a cross-linkable electrophilic compound, a nucleophilic compound, and an amphiphilic poly(alkyl)ene glycol block polymer in an amount of 20% (w/v) or less of the sealant composition. The composition can optionally include a viscosifier, in an amount of 0.1% to 1.0% (w/v) of the sealant composition.
    Type: Application
    Filed: May 6, 2022
    Publication date: November 9, 2023
    Inventors: Sai Veruva, Salim Ghodbane, Thomas Weindl
  • ANTI-HLA-G ANTIBODIES AND USE THEREOF
    Publication number: 20230159642
    Abstract: The present invention relates to antibodies that bind to human HLA-G, multispecific antibodies thereof, their preparation, formulations, and methods of using the same.
    Type: Application
    Filed: October 18, 2022
    Publication date: May 25, 2023
    Inventors: Alexander BUJOTZEK, Alejandro CARPY GUTIERREZ CIRLOS, Anne FREIMOSER-GRUNDSCHOBER, Carina HAGE, Thomas HOFER, Silke KIRCHNER, Meher MAJETY, Ekkehard MOESSNER, Christiane NEUMANN, Christian SPICK, Georg TIEFENTHALER, Thomas WEINDL
  • Two Component Sealing Systems Including Synthetic Matrices and Biosynthetic Adhesives
    Publication number: 20220331475
    Abstract: The present invention is directed to a hemostatic patch comprising a porous substrate and at least a pair of co-reactive polymer reagents comprising at least one nucleophilic polyalkylene oxide based component and at least one electrophilic polyalkylene oxide-based on the porous substrate in a molar ratio of about 0.2 to about 0.9:1 of primary nucleophilic groups in excess to available electrophilic groups. The present invention is also directed to processes for the manufacture and use of such hemostatic patches.
    Type: Application
    Filed: February 9, 2022
    Publication date: October 20, 2022
    Inventors: Nir Nativ, Thomas Weindl, Benjamin D. Fitz, Gerard Llanos, Guanghui Zhang, Yi-Lan Wang, Meng Deng
  • Anti-HLA-G antibodies and use thereof
    Publication number: 20220213199
    Abstract: The present invention relates antibodies that bind to human HLA-G, multispecific antibodies thereof, their preparation, formulations and methods of using the same.
    Type: Application
    Filed: December 15, 2021
    Publication date: July 7, 2022
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Alexander Bujotzek, Alejandro Carpy Gutierrez Cirlos, Anne Freimoser-Grundschober, Carina Hage, Thomas Hofer, Silke Kirchner, Meher Majety, Ekkehard Moessner, Christiane Neumann, Christian Spick, Georg Tiefenthaler, Thomas Weindl
  • Sealant Dressing with Removable Intermediate Separating Layer
    Publication number: 20220023488
    Abstract: The present invention is directed to medical devices having a first porous substrate layer with at least a surface coating thereon of a first co-reactive component and a second substrate layer with at least a surface coating layer of a second co-reactive component that reacts with the first co-reactive component, and a removable barrier layer positioned between the first substrate layer and second substrate layer and in contact with said first substrate layer and said second substrate layer.
    Type: Application
    Filed: July 21, 2020
    Publication date: January 27, 2022
    Inventors: Nir Nativ, Gerard Llanos, Thomas Weindl, Sai Veruva