Abstract: A patient interface system for positioning a patient's eye opposite a laser device for laser surgery is disclosed, including a patient interface for coupling to the patient's eye and a patient interface holder for arranging the patient interface on the laser device. The patient interface holder includes a holder device with an engaging device for reversibly coupling the patient interface to the patient interface holder, and to position the patient interface relative to the patient interface holder with a second positioning device. The engaging device has a spring-loaded engaging body that cooperates with an associated engaging surface of the second positioning device of the patient interface in the coupled state of the patient interface. A method for coupling a patient interface with a patient interface holder of a patient interface system, as well as a patient interface and a patient interface holder for a patient interface system are also disclosed.

Abstract: A patient interface system for positioning a patient's eye relative to a laser device for laser surgery is disclosed that includes a patient interface for coupling to the patient's eye, and a patient interface holder for arranging the patient interface on the laser device. The patient interface holder has a suction duct for connecting to a suction device, and the patient interface has a fluid-conducting device that couples to the patient interface holder, and when in the coupled state, together form a fluid path which fluidically couples the suction duct to the patient interface in order to hold a first positioning device of the patient interface against the patient's eye by a relative negative pressure generated by the suction device. A method is disclosed for coupling a patient interface to a patient interface holder, and a patient interface. A patient interface holder is also disclosed.

Abstract: A patient interface system is disclosed for positioning a patient's eye opposite a laser device for laser surgery. The system including a patient interface for coupling to the patient's eye and a patient interface holder for arranging the patient interface on the laser device. The patient interface holder includes a connection device for coupling a camera system. The patient interface holder and the patient interface have corresponding channels that delimit an optical path between the connection device and the patient interface. The channel of the patient interface is arranged such that is runs at least partially on an outer circumference of a suction cup part of the patient interface. Also disclosed are a camera system, a method for coupling a patient interface with a patient interface holder, as well as a patient interface and a patient interface holder, for a patient interface system.

Abstract: The invention relates to a treatment apparatus (1) for an eye treatment, at least comprising: at least one laser beam source (3) configured for emission of a laser beam (2), at least one beam exit device (9), which is configured to direct the laser beam (2) to an eye (11) to be treated, at least one transfer optics (6), which is configured to feed the laser beam (2) along a respective optical path (21) to the at least one beam exit device (9), and a control device (14), which is configured to retrieve a predetermined eye treatment configuration (15) from a storage device (13), on which multiple eye treatment configurations (12) are stored, to adjust the at least one laser beam source (3) for generating the laser beam (2) of a pulse duration (4) to be adjusted according to the predetermined eye treatment configuration (15) of the eye treatment configurations (12), and to adjust the at least one transfer optics (6) for providing a predetermined numerical aperture (10) of the transfer optics (6) according to the

Abstract: A method for producing a model for the application of radiation to a body surface area of a living being for cosmetic or therapeutic purposes is provided. The method includes defining a body surface area to which radiation shall be applied; producing a model having at least one surface which has the inverted shape of the defined body surface area, so that the model is configured to fit on the defined body surface area; and providing a radioactive isotope to the model during its production or after its production. Further, the use of the model in a cosmetic treatment of the skin is provided. The model, for cosmetic or therapeutic purposes, includes a surface which has the inverted shape of a defined body surface area which shall be treated with radiation.

Abstract: Provided is a process of producing activated particles comprising 188Re-isotopes and/or 186Re-isotopes by irradiating non-volatile and water-insoluble starting particles comprising a rhenium compound with neutrons. Further provided is a process of producing corresponding non-volatile and water-insoluble starting particles. Further provided are respective starting particles and activated particles, respectively, and a composition comprising a plurality of activated particles. The activated particles, and the composition comprising same are suitable for use in radionuclide therapy, and for cosmetic applications.

Abstract: A patient interface system for positioning a patient's eye relative to a laser device for laser surgery is disclosed that includes a patient interface for coupling to the patient's eye, and a patient interface holder for arranging the patient interface on the laser device. The patient interface holder has a suction duct for connecting to a suction device, and the patient interface has a fluid-conducting device that couples to the patient interface holder, and when in the coupled state, together form a fluid path which fluidically couples the suction duct to the patient interface in order to hold a first positioning device of the patient interface against the patient's eye by a relative negative pressure generated by the suction device. A method is disclosed for coupling a patient interface to a patient interface holder, and a patient interface. A patient interface holder is also disclosed.

Abstract: The present invention relates to a method for controlling an eye surgical laser for the separation of a volume body with predefined interfaces from a human or animal cornea, comprising controlling the laser by means of a control device such that it emits pulsed laser pulses in a predefined pattern into the cornea, wherein the interfaces of the volume body to be separated are defined by the predefined pattern and the interfaces are generated by means of photodisruption, wherein the interfaces of the volume body are determined such that a pathological and/or unnaturally altered area within the stroma of the cornea is enclosed. Furthermore, the invention relates to a treatment device with at least one eye surgical laser for the separation of a predefined corneal volume with predefined interfaces of a human or animal eye by means of photodisruption and at least one control device for the laser or lasers, which is formed to execute the steps of the method according to the invention.

Abstract: A patient interface system is disclosed for positioning a patient's eye opposite a laser device for laser surgery. The system including a patient interface for coupling to the patient's eye and a patient interface holder for arranging the patient interface on the laser device. The patient interface holder includes a connection device for coupling a camera system. The patient interface holder and the patient interface have corresponding channels that delimit an optical path between the connection device and the patient interface. The channel of the patient interface is arranged such that is runs at least partially on an outer circumference of a suction cup part of the patient interface. Also disclosed are a camera system, a method for coupling a patient interface with a patient interface holder, as well as a patient interface and a patient interface holder, for a patient interface system.

Abstract: A patient interface system for positioning a patient's eye opposite a laser device for laser surgery is disclosed, including a patient interface for coupling to the patient's eye and a patient interface holder for arranging the patient interface on the laser device. The patient interface holder includes a holder device with an engaging device for reversibly coupling the patient interface to the patient interface holder, and to position the patient interface relative to the patient interface holder with a second positioning device. The engaging device has a spring-loaded engaging body that cooperates with an associated engaging surface of the second positioning device of the patient interface in the coupled state of the patient interface. A method for coupling a patient interface with a patient interface holder of a patient interface system, as well as a patient interface and a patient interface holder for a patient interface system are also disclosed.

Abstract: A method for producing a model for the application of radiation to a body surface area of a living being for cosmetic or therapeutic purposes is provided. The method includes defining a body surface area to which radiation shall be applied; producing a model having at least one surface which has the inverted shape of the defined body surface area, so that the model is configured to fit on the defined body surface area; and providing a radioactive isotope to the model during its production or after its production. Further, the use of the model in a cosmetic treatment of the skin is provided. The model, for cosmetic or therapeutic purposes, includes a surface which has the inverted shape of a defined body surface area which shall be treated with radiation.

Abstract: Provided is a process of producing activated particles comprising 188Re-isotopes and/or 186Re-isotopes by irradiating non-volatile and water-insoluble starting particles comprising a rhenium compound with neutrons. Further provided is a process of producing corresponding non-volatile and water-insoluble starting particles. Further provided are respective starting particles and activated particles, respectively, and a composition comprising a plurality of activated particles. The activated particles, and the composition comprising same are suitable for use in radionuclide therapy, and for cosmetic applications.

Abstract: An image generating apparatus for image generation is provided. The image generating apparatus includes a movable detector for detecting nuclear radiation during a detection period and an evaluation system. The evaluation system includes an interface system for transmitting detector data to the evaluation system. The detector data include information about the detected radiation for image generation. The evaluation system further includes a data memory portion for storing the detector data. The evaluation system further includes a program memory portion with a program for repeatedly determining at least one quality value with respect to image generation during the detection period.

Abstract: A system for endoscopic nuclear imaging, a nuclear probe and related methods are provided. In one embodiment, a system includes a movable endoscopic nuclear probe which comprises a collimator and a detector, the endoscopic nuclear probe having an elongated body with a longitudinal axis (X), wherein the detector and the collimator are arranged on the elongated body, and the collimator having a field of view with an axis (Y) and the axis (Y) is angled with respect to the axis (X) of the elongated body of the endoscopic nuclear probe; means for determining the position and orientation of the elongated body of the endoscopic nuclear probe; an evaluation unit including means for computationally determining an actual position and actual orientation of the elongated body of the endoscopic nuclear probe; and a program storage section and means for computing at least one quality parameter of the image.

Abstract: A nuclear image system for updating an original nuclear image, the nuclear image system comprising: a data memory for storing the original three-dimensional nuclear image; a nuclear radiation detector, which is movable along a freely variable path, for measuring nuclear radiation, in order to obtain nuclear radiation values; a tracking system for tracking the nuclear radiation detector while measuring the nuclear radiation, so that detector coordinates are obtained which indicate a posture of the tracked nuclear radiation detector in relation to an image coordinate system of the nuclear image; a nuclear data input configured to receive the nuclear radiation values from the nuclear radiation detector and the detector coordinates from the tracking system, and to associate the nuclear radiation values with the respective detector coordinates; and an image updating module including an updating rule for changing the original nuclear image on the basis of the nuclear radiation values and the detector coordinates, w

Abstract: An image generating apparatus for image generation is provided. The image generating apparatus includes a movable detector for detecting nuclear radiation during a detection period and an evaluation system. The evaluation system includes an interface system for transmitting detector data to the evaluation system. The detector data include information about the detected radiation for image generation. The evaluation system further includes a data memory portion for storing the detector data. The evaluation system further includes a program memory portion with a program for repeatedly determining at least one quality value with respect to image generation during the detection period.

Abstract: A combined nuclear and ultrasonic system for hybrid imaging is proposed. It comprises a hand-held nuclear radiation detector, a hand-held ultrasonic probe, a nuclear tracking system for tracking the nuclear radiation detector while measuring a nuclear radiation and obtaining nuclear radiation detector coordinates representing a position of the tracked nuclear radiation detector in relation to an image coordinate system of a hybrid image, an ultrasonic tracking system for tracking of the ultrasonic probe during the receiving of ultrasonic signals so that ultrasonic probe coordinates are obtained which represent a position of the tracked ultrasonic probe in relation to an image coordinate system of the hybrid image, and a data acquisition module, which gathers the nuclear radiation detector measurements, nuclear radiation detector coordinates, ultrasonic signals from the ultrasonic probe, and ultrasonic probe coordinates, and matches them with an image coordinate system of a hybrid image.

Abstract: A device for combined optical and nuclear image comprises a nuclear image acquisition module and a reference image acquisition module. The reference image acquisition module has: an optical image sensor; and an optical imaging system for deflecting the optical radiation from a reference field of view to the image sensor, wherein the optical imaging system comprises a mirror for the optical radiation, which mirror is arranged between the reference field of view and the optical image sensor. On the image sensor, a respective image area assigned to at least one of nuclear partial fields of view. The optical imaging system is arranged such that the optical radiation coming from the at least one nuclear partial field of view is deflected substantially exactly to the respectively assigned of the image areas.

Abstract: A diagnostic device for computer tomography and nuclear imaging of a body is provided. The device includes at least one movable robot arm, an x-ray source, and a detector for nuclear radiation. Further, a method for the 3D imaging of a body is provided. The method includes irradiating the body by a moving x-ray source, and acquiring nuclear emission data via readings from a moving nuclear detector, supervising the poses of the x-ray source and the nuclear detector, synchronizing the readings from the nuclear detector and the x-ray source with their respective poses, and calculating 3D images by using the acquired information from the x-ray source and from the nuclear detector.

Abstract: A nuclear image system for updating an original nuclear image, the nuclear image system comprising: a data memory for storing the original three-dimensional nuclear image; a nuclear radiation detector, which is movable along a freely variable path, for measuring nuclear radiation, in order to obtain nuclear radiation values; a tracking system for tracking the nuclear radiation detector while measuring the nuclear radiation, so that detector coordinates are obtained which indicate a posture of the tracked nuclear radiation detector in relation to an image coordinate system of the nuclear image; a nuclear data input configured to receive the nuclear radiation values from the nuclear radiation detector and the detector coordinates from the tracking system, and to associate the nuclear radiation values with the respective detector coordinates; and an image updating module including an updating rule for changing the original nuclear image on the basis of the nuclear radiation values and the detector coordinates, w