Patents by Inventor Thomas Wiglenda

Thomas Wiglenda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Enhancers of protein degradation
    Patent number: 9512066
    Abstract: The present invention relates to compounds suitable for modulating huntingtin protein processing and useful for treating or preventing huntingtin-related disorders. The invention provides pharmaceutical compositions comprising said compounds and methods of syntheses thereof.
    Type: Grant
    Filed: August 19, 2010
    Date of Patent: December 6, 2016
    Assignee: MAX-DELBRUCK-CENTRUM FUR MOLEKULARE MEDIZIN
    Inventors: Erich Wanker, Thomas Wiglenda, Julius Tachu Babila, Annett Boddrich, Michael Schmidt, Sandra Neuendorf, Franziska Schiele
  • Azo compounds reducing formation and toxicity of amyloid beta aggregation intermediates
    Patent number: 8974768
    Abstract: The present invention relates to compounds suitable as modulators of protein misfolding and/or protein aggregation. The compounds are particularly suitable as inhibitors of amyloid aggregate formation and/or modulators of amyloid surface properties, and/or as activators of degradation or reduction of amyloid aggregates.
    Type: Grant
    Filed: March 23, 2011
    Date of Patent: March 10, 2015
    Assignee: Max-Delbrueck-Centrum fuer Molekulare Medizin
    Inventors: Erich Wanker, Thomas Wiglenda, Julius Tachu Babila, Annett Boeddrich, Michael Schmidt, Franziska Schiele
  • AZO COMPOUNDS REDUCING FORMATION AND TOXICITY OF AMYLOID BETA AGGREGATION INTERMEDIATES
    Publication number: 20130078186
    Abstract: The present invention relates to compounds suitable as modulators of protein misfolding and/or protein aggregation. The compounds are particularly suitable as inhibitors of amyloid aggregate formation and/or modulators of amyloid surface properties, and/or as activators of degradation or reduction of amyloid aggregates.
    Type: Application
    Filed: March 23, 2011
    Publication date: March 28, 2013
    Applicant: MAX-DELBRUECK-CENTRUM FUER MOLEKULARE MEDIZIN
    Inventors: Erich Wanker, Thomas Wiglenda, Julius Tachu Babila, Annett Boeddrich, Michael Schmidt, Franziska Schiele
  • Enhancers of Protein Degradation
    Publication number: 20120282629
    Abstract: The present invention relates to compounds suitable for modulating huntingtin protein processing and useful for treating or preventing huntingtin-related disorders. The invention provides pharmaceutical compositions comprising said compounds and methods of syntheses thereof.
    Type: Application
    Filed: August 19, 2010
    Publication date: November 8, 2012
    Applicant: MAX-DELBRUCK-CENTRUM FUR MOLEKULARE MEDIZIN
    Inventors: Erich Wanker, Thomas Wiglenda, Julius Tachu Babila, Annett Boddrich, Michael Schmidt, Sandra Neuendorf, Franziska Schiele