Patents by Inventor Thomas Willnow

Thomas Willnow has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD OF UPREGULATING SORLA FOR THE TREATMENT OF ALZHEIMER'S DISEASE
    Publication number: 20110104165
    Abstract: The present invention is directed to use of an agent capable of upregulating the Vps10p-domain receptor SorLA. In particular, the present invention relates to use of CTGF and/or BDNF and/or fragments and/or variants thereof for the inhibition of plaque formation thereby being useful in the treatment of Alzheimer's Disease or other disorders associated with elevated of amyloid beta or amyloid plaque.
    Type: Application
    Filed: September 10, 2009
    Publication date: May 5, 2011
    Applicant: H. LUNDBECK A/S
    Inventor: Thomas Willnow
  • METHOD OF TREATING SIDE EFFECTS INDUCED BY THERAPEUTIC AGENTS
    Publication number: 20080153753
    Abstract: The invention relates to agents for the prevention of organ damage, in particular of the kidneys and the inner ear, induced by the administration of aminoglycosides. Agents according to the invention are all substances which are megalin and/or cubilin antagonists (inhibitors). In particular, these are molecules (compounds) having polybasic structures which bind to megalin and inhibit the binding of aminoglycosides and related substances.
    Type: Application
    Filed: March 5, 2008
    Publication date: June 26, 2008
    Inventor: Thomas Willnow
  • Method of treating side effects induced by therapeutic agents
    Patent number: 7345018
    Abstract: The invention relates to agents for the prevention of organ damage, in particular of the kidneys and the inner ear, induced by the administration of aminoglycosides. Agents according to the invention are all substances which are megalin and/or cubilin antagonists (inhibitors). In particular, these are molecules (compounds) having polybasic structures which bind to megalin and inhibit the binding of aminoglycosides and related substances.
    Type: Grant
    Filed: April 25, 2002
    Date of Patent: March 18, 2008
    Assignee: Reception ApS
    Inventor: Thomas Willnow
  • Modulation of steroid hormone uptake
    Publication number: 20040198705
    Abstract: The present invention discloses that cells, such as mammalian cells actively can take up steroid hormones/steroid hormone binding protein complexes via steroid hormone binding protein receptors and/or co-receptors. Furthermore, the invention relates to methods for screening for compounds, which alters uptake of such complexes, compounds identified by said methods as well as methods for treatment using said compounds and uses of said compounds for the preparation of a medicament.
    Type: Application
    Filed: May 4, 2004
    Publication date: October 7, 2004
    Inventors: Thomas Willnow, Anders Nykjaer
  • Agents for the prevention of organ damage induced by therapeutic agents
    Publication number: 20030202974
    Abstract: The invention relates to agents for the prevention of organ damage, in particular of the kidneys and the inner ear, induced by the administration of aminoglycosides. Agents according to the invention are all substances which are megalin and/or cubilin antagonists (inhibitors). In particular, these are molecules (compounds) having polybasic structures which bind to megalin and inhibit the binding of aminoglycosides and related substances.
    Type: Application
    Filed: April 25, 2002
    Publication date: October 30, 2003
    Applicant: Max-Delbruck-Centrum fur Molekulare Medizin
    Inventor: Thomas Willnow