Patents by Inventor Thomas Witzel

Thomas Witzel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11874353
    Abstract: Described here are systems and methods for producing images with a magnetic resonance imaging (“MRI”) system using a high-resolution, motion-robust, artifact-free segmented echo planar imaging (“EPI”) technique. In particular, a fast low angle excitation echo planar imaging technique (“FLEET”) using variable flip angle (“VFA”) radio frequency (“RF”) excitation pulses that are recursively designed to have a flat magnitude and phase profile across a slice for a range of different flip angles by accounting for longitudinal magnetization remaining after each preceding RF pulse is applied.
    Type: Grant
    Filed: March 27, 2020
    Date of Patent: January 16, 2024
    Assignee: The General Hospital Corporation
    Inventors: Avery J. L. Berman, Jonathan R. Polimeni, William A. Grissom, Kawin Setsompop, Thomas Witzel
  • Publication number: 20240005514
    Abstract: During operation, a system may obtain first and second magnetic resonance (MR) measurements associated with a biological lifeform, where the first and second MR measurements were acquired while the biological lifeform engaged in free breathing and/or without prospective gating based on a cardiac rhythm of the biological lifeform, and the first and second MR measurements were acquired at different times. Then, the system may dynamically determine first and second instances of one or more anatomical structures associated with the biological lifeform based at least in part on the first and second MR measurements, and a segmentation technique. Next, the system may perform a quantitative comparison of the first instance of the one or more anatomical structures and the second instance of the one or more anatomical structures, where the quantitative comparison has an uncertainty of less than a predefined value.
    Type: Application
    Filed: June 29, 2023
    Publication date: January 4, 2024
    Inventors: Jeffrey H. Kaditz, Aikaterini Kotrosou, Gordon Duffley, Blake Edwin Zimmerman, Thomas Witzel, Adam Patrick Harrison
  • Patent number: 11733335
    Abstract: A method is proposed for recording diagnostic measurement data of a head of an examination object in head imaging via a magnetic resonance device. The method comprises performing an overview scan of the head of the examination object, wherein overview measurement data is acquired in the overview scan and performing various diagnostic scans of the head of the examination object based on the acquired overview measurement data, wherein diagnostic measurement data is acquired in the various diagnostic scans.
    Type: Grant
    Filed: August 23, 2021
    Date of Patent: August 22, 2023
    Assignees: Siemens Healthcare GmbH, The General Hospital Corporation
    Inventors: Keith Aaron Heberlein, Thomas Witzel
  • Publication number: 20230204700
    Abstract: A computer system that performs a sparsity technique is described. During operation, the computer system accesses or obtains information associated with non-invasive measurements performed on at least an individual, historical non-invasive measurements, and a dictionary of predetermined features or basis functions associated with the historical non-invasive measurements. Note that the non-invasive measurements and the historical non-invasive measurements may include or correspond to magnetic resonance (MR) measurements. For example, the MR measurements may include magnetic resonance imaging (MRI) scans. Then, the computer system updates the dictionary of predetermined features based at least in part on the non-invasive measurements and the historical non-invasive measurements, where the updating includes performing a minimization technique with a cost function having an L2-norm term and an L0-norm term.
    Type: Application
    Filed: February 22, 2023
    Publication date: June 29, 2023
    Inventors: Guanhua Wang, Matteo Alessandro Francavilla, Thomas Witzel, Jeffrey H. Kaditz
  • Patent number: 11614508
    Abstract: A computer system that performs a sparsity technique is described. During operation, the computer system accesses or obtains information associated with non-invasive measurements performed on at least an individual, historical non-invasive measurements, and a dictionary of predetermined features or basis functions associated with the historical non-invasive measurements. Note that the non-invasive measurements and the historical non-invasive measurements may include or correspond to magnetic resonance (MR) measurements. For example, the MR measurements may include magnetic resonance imaging (MRI) scans. Then, the computer system updates the dictionary of predetermined features based at least in part on the non-invasive measurements and the historical non-invasive measurements, where the updating includes performing a minimization technique with a cost function having an L2-norm term and an L0-norm term.
    Type: Grant
    Filed: October 25, 2021
    Date of Patent: March 28, 2023
    Assignee: Q Bio, Inc.
    Inventors: Guanhua Wang, Matteo Alessandro Francavilla, Thomas Witzel, Jeffrey H. Kaditz
  • Publication number: 20220304582
    Abstract: Systems and methods for localized pseudo-continuous ASL (pCASL) of arterial blood local multi-coil arrays in an MRI system allow a series of pulses to selectively label blood with an on-resonance magnetic field in one or more arteries in a labeling plane while masking blood in others with an off-resonance magnetic field. This allows perfusion imaging and is well suited for imaging of cerebral blood flow.
    Type: Application
    Filed: March 28, 2022
    Publication date: September 29, 2022
    Inventors: Yulin Chang, Jason Stockmann, Thomas Witzel, Marta Vidorreta Diaz De Cerio, John Detre, Lincoln Craven-Brightman
  • Publication number: 20220179024
    Abstract: Described here are systems and methods for producing images with a magnetic resonance imaging (“MRI”) system using a high-resolution, motion-robust, artifact-free segmented echo planar imaging (“EPI”) technique. In particular, a fast low angle excitation echo planar imaging technique (“FLEET”) using variable flip angle (“VFA”) radio frequency (“RF”) excitation pulses that are recursively designed to have a flat magnitude and phase profile across a slice for a range of different flip angles by accounting for longitudinal magnetization remaining after each preceding RF pulse is applied.
    Type: Application
    Filed: March 27, 2020
    Publication date: June 9, 2022
    Inventors: Avery J.L. Berman, Jonathan R. Polimeni, William A. Grissom, Kawin Setsompop, Thomas Witzel
  • Publication number: 20220011390
    Abstract: A method is proposed for recording diagnostic measurement data of a head of an examination object in head imaging via a magnetic resonance device. The method comprises performing an overview scan of the head of the examination object, wherein overview measurement data is acquired in the overview scan and performing various diagnostic scans of the head of the examination object based on the acquired overview measurement data, wherein diagnostic measurement data is acquired in the various diagnostic scans.
    Type: Application
    Filed: August 23, 2021
    Publication date: January 13, 2022
    Applicants: Siemens Healthcare GmbH, The General Hospital Corporation
    Inventors: Keith Aaron HEBERLEIN, Thomas WITZEL
  • Patent number: 11129541
    Abstract: A method is proposed for recording diagnostic measurement data of a head of an examination object in head imaging via a magnetic resonance device. The method comprises performing an overview scan of the head of the examination object, wherein overview measurement data is acquired in the overview scan and performing various diagnostic scans of the head of the examination object based on the acquired overview measurement data, wherein diagnostic measurement data is acquired in the various diagnostic scans.
    Type: Grant
    Filed: September 5, 2017
    Date of Patent: September 28, 2021
    Assignees: SIEMENS HEALTHCARE GMBH, THE GENERAL HOSPITAL CORPORATION
    Inventors: Keith Aaron Heberlein, Thomas Witzel
  • Patent number: 10908248
    Abstract: Systems and methods for simultaneously acquiring high-resolution images of a subject from multiple different slice locations using magnetic resonance imaging (“MRI”) are described. The present invention overcomes the aforementioned drawbacks by providing method for producing a plurality of images of a subject with a magnetic resonance imaging (“MRI”) system. A radio frequency (RF) excitation field is applied by the MRI system to a portion of a subject that includes a plurality of slice locations. First data are simultaneously acquired from each of the plurality of slice locations by the MRI system.
    Type: Grant
    Filed: October 2, 2015
    Date of Patent: February 2, 2021
    Assignee: The General Hospital Corporation
    Inventors: Kawin Setsompop, Berkin Bilgic, Lawrence L. Wald, Thomas Witzel
  • Patent number: 10565226
    Abstract: An Application Program Interface (API) manages synchronization and replication of master data of a system with different consumers. An API engine is configured to receive from the third party, a query including content information and date-relevant information including a start date, an end date, and a date of last synchronization. The API engine processes the query to access the database and produce a query result replicating only data changes affecting that period or a previous time. The consumer thus specifies the time period in which to consider changes to the stored database data, and the API calculates the delta according to that period. In this manner complex, time-dependent delta calculation and filtering logic can be implemented in the API without requiring substantial logic or additional data persistence in middleware. Particular embodiments may facilitate efficient synchronized replication of employment data to outside (e.g., payroll, benefits) providers.
    Type: Grant
    Filed: February 1, 2016
    Date of Patent: February 18, 2020
    Assignee: SuccessFactors, Inc.
    Inventors: Daniel Goldmann, Esther Landes, Mario Andy Mueller, Klemens Schmid, Thomas Witzel, Joachim Pfeifer, Matthias Klauer, Oleg Loewen
  • Patent number: 10228434
    Abstract: Described here are systems and methods for producing images with a magnetic resonance imaging (“MRI”) system using a high-resolution, motion-robust, artifact-free segmented echo planar imaging (“EPI”) technique. In particular, a fast low angle excitation echo planar imaging technique (“FLEET”) using variable flip angle (“VFA”) radio frequency (“RF”) excitation pulses that are specifically designed to have a flat magnitude and phase profile across a slice for a range of different flip angles.
    Type: Grant
    Filed: May 3, 2017
    Date of Patent: March 12, 2019
    Assignee: The General Hospital Corporation
    Inventors: Jonathan R Polimeni, Thomas Witzel
  • Patent number: 9983282
    Abstract: Spin-lock T1?-weighted images of a subject are acquired and processed to produce an image that is indicative of bioelectromagnetic activity in the subject. A spin-lock RF field B1? is produced such that the Larmor frequency in the rotating frame corresponds to the expected frequency of the bioelectromagnetic activity. As a result, the magnetic field fluctuations generated by the bioelectromagnetic currents shorten the T1? of the surrounding tissue, creating a contrast mechanism that is seen as a reduced MR signal in the T1?-weighted image that is produced.
    Type: Grant
    Filed: November 21, 2007
    Date of Patent: May 29, 2018
    Assignee: The General Hospital Corporation
    Inventors: Lawrence L. Wald, Thomas Witzel, Bruce R. Rosen
  • Publication number: 20180140218
    Abstract: A method is proposed for recording diagnostic measurement data of a head of an examination object in head imaging via a magnetic resonance device. The method comprises performing an overview scan of the head of the examination object, wherein overview measurement data is acquired in the overview scan and performing various diagnostic scans of the head of the examination object based on the acquired overview measurement data, wherein diagnostic measurement data is acquired in the various diagnostic scans.
    Type: Application
    Filed: September 5, 2017
    Publication date: May 24, 2018
    Applicants: Siemens Healthcare GmbH, The General Hospital Corporation
    Inventors: Keith Aaron HEBERLEIN, Thomas WITZEL
  • Publication number: 20180100908
    Abstract: Systems and methods for simultaneously acquiring high-resolution images of a subject from multiple different slice locations using magnetic resonance imaging (“MRI”) are described. The present invention overcomes the aforementioned drawbacks by providing method for producing a plurality of images of a subject with a magnetic resonance imaging (“MRI”) system. A radio frequency (RF) excitation field is applied by the MRI system to a portion of a subject that includes a plurality of slice locations. First data are simultaneously acquired from each of the plurality of slice locations by the MRI system.
    Type: Application
    Filed: October 2, 2015
    Publication date: April 12, 2018
    Inventors: Kawin Setsompop, Berkin Bilgic, Lawrence L. Wald, Thomas Witzel
  • Publication number: 20170322279
    Abstract: Described here are systems and methods for producing images with a magnetic resonance imaging (“MRI”) system using a high-resolution, motion-robust, artifact-free segmented echo planar imaging (“EPI”) technique. In particular, a fast low angle excitation echo planar imaging technique (“FLEET”) using variable flip angle (“VFA”) radio frequency (“RF”) excitation pulses that are specifically designed to have a flat magnitude and phase profile across a slice for a range of different flip angles.
    Type: Application
    Filed: May 3, 2017
    Publication date: November 9, 2017
    Inventors: Jonathan R. Polimeni, Thomas Witzel
  • Publication number: 20170220658
    Abstract: An Application Program Interface (API) manages synchronization and replication of master data of a system with different consumers. An API engine is configured to receive from the third party, a query including content information and date-relevant information including a start date, an end date, and a date of last synchronization. The API engine processes the query to access the database and produce a query result replicating only data changes affecting that period or a previous time. The consumer thus specifies the time period in which to consider changes to the stored database data, and the API calculates the delta according to that period. In this manner complex, time-dependent delta calculation and filtering logic can be implemented in the API without requiring substantial logic or additional data persistence in middleware. Particular embodiments may facilitate efficient synchronized replication of employment data to outside (e.g., payroll, benefits) providers.
    Type: Application
    Filed: February 1, 2016
    Publication date: August 3, 2017
    Inventors: Daniel Goldmann, Esther Landes, Mario Andy Mueller, Klemens Schmid, Thomas Witzel, Joachim Pfeifer, Matthias Klauer, Oleg Loewen
  • Patent number: 9588208
    Abstract: A method for accelerated segmented magnetic resonance (MR) image data acquisition includes using a plurality of RF pulses to excite one or more slices of an anatomical area of interest according to a predetermined slice acceleration factor. Next, a collapsed image comprising the slices is acquired using a consecutive segment acquisition process. Then, a parallel image reconstruction method is applied to the collapsed image to separate the collapsed image into a plurality of slice images.
    Type: Grant
    Filed: May 7, 2014
    Date of Patent: March 7, 2017
    Assignees: National Institutes of Health (NIH), U.S. Dept. of Health and Human Services (DHHS), U.S. Government NIH Division of Extramural Inventions and Technology Resources (DEITR), Siemens Healthcare GmbH
    Inventors: Jonathan Rizzo Polimeni, Himanshu Bhat, Keith Aaron Heberlein, Kawin Setsompop, Thomas Witzel, Stephen Farman Cauley
  • Patent number: 9367826
    Abstract: A business object model, which reflects data that is used during a given business transaction, is utilized to generate interfaces. This business object model facilitates commercial transactions by providing consistent interfaces that are suitable for use across industries, across businesses, and across different departments within a business during a business transaction. In some operations, software creates, updates, or otherwise processes information related to an entitlement product business object.
    Type: Grant
    Filed: June 28, 2012
    Date of Patent: June 14, 2016
    Assignee: SAP SE
    Inventors: Torsten Buecheler, Matthias Becker, Oliver Berger, Knut Heusermann, Christian Hohmann, Steffen Witt, Esther Landes, Thomas Witzel, Marcel Steinleitner
  • Publication number: 20150323634
    Abstract: A method for accelerated segmented magnetic resonance (MR) image data acquisition includes using a plurality of RF pulses to excite one or more slices of an anatomical area of interest according to a predetermined slice acceleration factor. Next, a collapsed image comprising the slices is acquired using a consecutive segment acquisition process. Then, a parallel image reconstruction method is applied to the collapsed image to separate the collapsed image into a plurality of slice images.
    Type: Application
    Filed: May 7, 2014
    Publication date: November 12, 2015
    Applicants: Massachusetts General Hospital, Siemens Medical Solutions USA, Inc.
    Inventors: Jonathan Rizzo Polimeni, Himanshu Bhat, Keith Aaron Heberlein, Kawin Setsompop, Thomas Witzel, Stephen Farman Cauley