Patents by Inventor Thomas Yun-Chung Leung

Thomas Yun-Chung Leung has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modified ?-lactamases and uses thereof
    Patent number: 7323303
    Abstract: A tool that can screen bacteria for ?-lactamases against a panel of various antibiotics is desirable. A biosensor incorporating an indicator molecule into ?-lactamases may achieve this purpose, but it requires that the attached indicator molecule must not impair the binding affinity of the protein to a great extent to provide a higher sensitivity. A modified ?-lactamases with a residue on the ?-loop or outside the ?-loop but close to the active site of ?-lactamase being replaced by a reactive residue is developed in this invention.
    Type: Grant
    Filed: March 31, 2003
    Date of Patent: January 29, 2008
    Assignee: Hong Kong Polytechnic University
    Inventors: Kwok-Yin Wong, Thomas Yun-Chung Leung, Pak-Ho Chan