Patents by Inventor Thomas Zander

Thomas Zander has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190210576
    Abstract: A hydraulic block of a slip control system of a hydraulic vehicle brake system has receptacles for inlet valves and outlet valves of the slip control system arranged on a cover side, and receptacles for block valves, intake valves, and hydraulic accumulator on an opposite main side. All connecting bores for wheel brakes and a main brake cylinder are arranged on a transverse side and an eccentric chamber is arranged on an opposite transverse side of the hydraulic block.
    Type: Application
    Filed: September 6, 2017
    Publication date: July 11, 2019
    Inventors: Thomas Zander, Michael Loeffler
  • Publication number: 20190140523
    Abstract: A drive assembly has a housing block, on which there is arranged an electrical machine. The latter has a working shaft mounted in a shaft bore of the housing block and the rotational position of which is detected by a sensor device formed by a signal transmitter and a signal receiver comprising evaluation electronics. The shaft bore is closed by a cover, which is arranged between signal transmitter and signal receiver. The cover is formed in one piece with an electronics housing of the signal receiver. A centering device for the signal receiver is formed on the housing block on the electronics housing. The disclosed drive assembly simplifies the construction, functional testing and mounting of the signal receiver and at the same time improves the protection thereof against damaging environmental influences.
    Type: Application
    Filed: October 15, 2018
    Publication date: May 9, 2019
    Inventors: Michael Schlitzkus, Anna Wondrak, Helmut Seiband, Stefan Lehenberger, Thomas Zander, Valentin Notemann
  • Publication number: 20180170334
    Abstract: A hydraulic power unit for a slip control system of a vehicle hydraulic brake system includes a hydraulic block that is equipped with hydraulic constructional elements such as hydraulic pumps and solenoid valves of the slip control system and an electric motor that is configured to drive the hydraulic pumps. The power unit further includes hydraulic accumulators attached on the outside on the hydraulic block in a control unit housing arranged next to an electronic control unit of the slip control system in order to save installation space.
    Type: Application
    Filed: October 24, 2017
    Publication date: June 21, 2018
    Inventors: Michael Loeffler, Thomas Zander
  • Publication number: 20180065612
    Abstract: A hydraulic unit for a slip controller of a hydraulic vehicle brake system includes an electric motor, a plurality of hydraulic pumps, a hydraulic block, a plurality of solenoid valves, a rotation angle sensor, an electronic control unit, and a valve cover. The electric motor is positioned on a narrow side of the hydraulic block, and is configured to drive the hydraulic pumps. The electronic control unit includes a contacting mechanism, and is positioned in the valve cover. The electric motor and the solenoid valves are arranged so that the electric motor and electromagnets of the solenoid valves protrude to approximately a same extent from the hydraulic block to enable simple commutation with the rotation angle sensor and the contacting mechanism of the electronic control unit.
    Type: Application
    Filed: September 7, 2017
    Publication date: March 8, 2018
    Inventors: Michael Loeffler, Thomas Zander, Michael Schlitzkus
  • Publication number: 20180030547
    Abstract: The present invention provides a method for early detection of non-small cell lung cancer based on the abundance of RNAs from blood samples as well as diagnostic tools such as kits and arrays suitable for such method.
    Type: Application
    Filed: October 2, 2017
    Publication date: February 1, 2018
    Inventors: Andrea HOFMANN, Joachim L. SCHULTZE, Andrea STARATSCHEK-JOX, Jurgen WOLF, Thomas ZANDER
  • Publication number: 20150105276
    Abstract: The present invention provides a method for early detection of non-small cell lung cancer based on the abundance of RNAs from blood samples as well as diagnostic tools such as kits and arrays suitable for such method.
    Type: Application
    Filed: July 24, 2014
    Publication date: April 16, 2015
    Inventors: Andrea HOFMANN, Joachim L. Schultze, Andrea Staratschek-Jox, Jurgen Wolf, Thomas Zander
  • Publication number: 20150099643
    Abstract: The invention pertains to a method for diagnosing or detecting lung cancer in human subjects based on ribonucleic acid (RNA) expression, in particular based on RNA from blood. The invention discloses 361 genes which are differentially expressed in blood from lung cancer patients and discloses that at least 4 of the mRNAs must be determined in order to have an AUC of at least 0.8.
    Type: Application
    Filed: July 10, 2014
    Publication date: April 9, 2015
    Inventors: Andrea HOFMANN, Joachim L. SCHULTZE, Jurgen WOLF, Andrea STARATSCHEK-JOX, Thomas ZANDER
  • Patent number: 8932580
    Abstract: The present invention relates to a method for the selective purification of bacterial cells and/or cell components, whereby the purification is performed by means of a solid support.
    Type: Grant
    Filed: July 28, 2009
    Date of Patent: January 13, 2015
    Assignees: Hyglos Invest GmbH, Biomerieux S.A.
    Inventors: Michael Schutz, Renate Grassl, Roman Meyer, Sibylle Frick, Ingrid Robl, Thomas Zander, Stefan Miller
  • Publication number: 20130023420
    Abstract: The present invention relates to a combination of cell lines as well as a method of selecting (a) cell(s), (a) tissue(s) or (a) cell culture(s) with susceptibility to an HSP90 inhibitor anti-tumor agent. Also a method for determining the responsiveness of a mammalian tumor cell or cancer cell or collection of cells or cell lines to treatment with a drug such as an HSP90 inhibitor anti-tumor agent is described herein.
    Type: Application
    Filed: February 14, 2012
    Publication date: January 24, 2013
    Inventors: Roman Thomas, Kathrin Maring, Thomas Zander, Peter Frommolt, Kwok-kin Wong
  • Publication number: 20110319415
    Abstract: The present invention relates to a method of selecting (a) cell(s), (a) tissue(s) or (a) cell culture(s) with susceptibility to an HSP90 inhibitor. Also a method for determining the responsiveness of a mammalian tumor cell or cancer cell to treatment with an HSP90 inhibitor is described herein. In particular, the present invention provides for an in vitro method for the identification of a responder for or a patient sensitive to an HSP90 inhibitor and uses of an oligo- or polynucleotide capable of detecting (an) activating mutation(s) in the KRAS gene are provided. The present invention also relates to a method of monitoring the efficacy of a treatment of a cancer characterized by the presence of at least one activating mutation in the KRAS gene, and. optionally, in the EGFR gene and/or the BRAF gene. In addition, a method of predicting the efficacy of a cancer treatment is described, in particular in a cancer that is characterized by the presence of at least one activating mutation in the KRAS gene. and.
    Type: Application
    Filed: August 17, 2009
    Publication date: December 29, 2011
    Applicants: Universit+e,uml a+ee t zu K+e,uml o+ee ln, Max-Planck-Gesellschaft zur F+e,uml o+ee rderung der Wissens
    Inventors: Roman Thomas, Kathrin Maring, Thomas Zander, Peter Frommolt, Kwok-kin Wong
  • Publication number: 20110183864
    Abstract: The present invention provides method for the prognosis or detection of lung cancer, notably for early detection of lung cancer, as well as a kit and a (micro) array suitable for said method.
    Type: Application
    Filed: July 15, 2009
    Publication date: July 28, 2011
    Applicants: UNIVERSITAET ZU KOELN, DKFZ DEUTSCHES KREBSFORSCHUNGSZENTRUM, STIFTUNG DES OEFFENTLICHEN RECHTS
    Inventors: Thomas Zander, Joachim L. Schultze, Juergen Wolf, Andrea Staratschek-Jox, Svenja Debey-Pascher, Daniela Maisel, Paolo Boffetta, Jakob Linseisen
  • Patent number: 7868144
    Abstract: The present invention relates to a method for unspecific enrichment of bacterial cells by means of cationic or anionic polymers and magnetic carriers.
    Type: Grant
    Filed: October 8, 2002
    Date of Patent: January 11, 2011
    Assignee: Hyglos Invest GmbH
    Inventors: Sabine Diller, Renate Grassl, Stefan Miller, Ingrid Robl, Michael Schütz, Thomas Zander
  • Publication number: 20100047895
    Abstract: The present invention relates to a method for the selective purification of bacterial cells and/or cell components, whereby the purification is performed by means of a solid support.
    Type: Application
    Filed: July 28, 2009
    Publication date: February 25, 2010
    Applicants: Hyglos Invest GmbH, bioMerieux S.A.
    Inventors: Michael Schütz, Renate Grassl, Roman Meyer, Sibylle Frick, Ingrid Robl, Thomas Zander, Stefan Miller
  • Patent number: 7579142
    Abstract: The present invention relates to a method for the selective purification of bacterial cells and/or cell components, whereby the purification is performed by means of a solid support.
    Type: Grant
    Filed: June 24, 2002
    Date of Patent: August 25, 2009
    Assignee: Profos AG
    Inventors: Michael Schütz, Renate Grassl, Roman Meyer, Sibylle Frick, Ingrid Robl, Thomas Zander, Stefan Miller
  • Publication number: 20050019827
    Abstract: The present invention relates to a method for unspecific enrichment of bacterial cells by means of cationic or anionic polymers and magnetic carriers.
    Type: Application
    Filed: October 8, 2002
    Publication date: January 27, 2005
    Inventors: Sabine Diller, Renate Grassl, Stefan Miller, Ingrid Robl, Michael Schultz, Thomas Zander
  • Publication number: 20040248298
    Abstract: The present invention relates to a method for the selective purification of bacterial cells and/or cell components, whereby the purification is performed by means of a solid support.
    Type: Application
    Filed: June 15, 2004
    Publication date: December 9, 2004
    Inventors: Michael Schutz, Renate Grassl, Roman Meyer, Sibylle Frick, Ingrid Robl, Thomas Zander, Stefan Miller
  • Patent number: 4948089
    Abstract: For the production of cross ties for switches, made of concrete in a prestressing fixture, a recoverable device for the emplacement of tubular components is built into the bottom of the concrete form for the tie, which comprises a pin and a nipple inserted detachably into its bottom. The nipple can be inserted into a corresponding bore of a base plate. The bore determines the position of a tube in the cross tie, has an upper and a lower stop with which it is anchored in the pin or the base plate, respectively, and can be firmly tensioned upon the base plate.
    Type: Grant
    Filed: April 27, 1988
    Date of Patent: August 14, 1990
    Assignee: Wayss & Freytag Aktiengesellschaft
    Inventors: Rolf Knodel, Frithjof Schimpff, Wolfgang Bergenthal, Thomas Zander