Patents by Inventor Thomasin C. Miller

Thomasin C. Miller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HIGH CETANE RENEWABLE FUELS
    Publication number: 20120132183
    Abstract: A method for reducing the emissions of a diesel engine using a RHE-diesel fuel.
    Type: Application
    Filed: November 28, 2011
    Publication date: May 31, 2012
    Applicant: CONOCOPHILLIPS COMPANY
    Inventors: Gary Clyde GUNTER, Edward T. CASEY, Thomasin C. MILLER, Matthew J. TRUITT
  • Flow method and apparatus for screening chemicals using micro x-ray fluorescence
    Patent number: 7929662
    Abstract: Method and apparatus for screening chemicals using micro x-ray fluorescence. A method for screening a mixture of potential pharmaceutical chemicals for binding to at least one target binder involves flow separating a solution of chemicals and target binders into separated components, exposing them to an x-ray excitation beam, detecting x-ray fluorescence signals from the components, and determining from the signals whether or not a binding event between a chemical and target binder has occurred.
    Type: Grant
    Filed: March 3, 2009
    Date of Patent: April 19, 2011
    Assignee: Los Alamos National Security, LLC
    Inventors: Benjamin P. Warner, George J. Havrilla, Thomasin C. Miller, Cris Lewis, Cynthia A. Mahan, Cyndi A. Wells
  • FLOW METHOD AND APPARATUS FOR SCREENING CHEMICALS USING MICRO X-RAY FLUORESCENCE
    Publication number: 20090175410
    Abstract: Method and apparatus for screening chemicals using micro x-ray fluorescence. A method for screening a mixture of potential pharmaceutical chemicals for binding to at least one target binder involves flow separating a solution of chemicals and target binders into separated components, exposing them to an x-ray excitation beam, detecting x-ray fluorescence signals from the components, and determining from the signals whether or not a binding event between a chemical and target binder has occurred.
    Type: Application
    Filed: March 3, 2009
    Publication date: July 9, 2009
    Applicant: LOS ALAMOS NATIONAL SECURITY, LLC
    Inventors: Benjamin P. WARNER, George J. HAVRILLA, Thomasin C. MILLER, Cris LEWIS, Cynthia A. MAHAN, Cyndi A. WELLS
  • Flow method and apparatus for screening chemicals using micro x-ray fluorescence
    Patent number: 7519145
    Abstract: Method and apparatus for screening chemicals using micro x-ray fluorescence. A method for screening a mixture of potential pharmaceutical chemicals for binding to at least one target binder involves flow-separating a solution of chemicals and target binders into separated components, exposing them to an x-ray excitation beam, detecting x-ray fluorescence signals from the components, and determining from the signals whether or not a binding event between a chemical and target binder has occurred.
    Type: Grant
    Filed: May 31, 2006
    Date of Patent: April 14, 2009
    Assignee: Los Alamos National Security, LLC
    Inventors: Benjamin P. Warner, George J. Havrilla, Thomasin C. Miller, Cris Lewis, Cynthia A. Mahan, Cyndi A. Wells
  • Method and apparatus for detecting chemical binding
    Patent number: 7241381
    Abstract: The method for screening binding between a target binder and potential pharmaceutical chemicals involves sending a solution (preferably an aqueous solution) of the target binder through a conduit to a size exclusion filter, the target binder being too large to pass through the size exclusion filter, and then sending a solution of one or more potential pharmaceutical chemicals (preferably an aqueous solution) through the same conduit to the size exclusion filter after target binder has collected on the filter. The potential pharmaceutical chemicals are small enough to pass through the filter. Afterwards, x-rays are sent from an x-ray source to the size exclusion filter, and if the potential pharmaceutical chemicals form a complex with the target binder, the complex produces an x-ray fluorescence signal having an intensity that indicates that a complex has formed.
    Type: Grant
    Filed: November 10, 2004
    Date of Patent: July 10, 2007
    Assignee: Los Alamos National Security, LLC
    Inventors: Benjamin P. Warner, George J. Havrilla, Thomasin C. Miller, Cyndi A. Wells
  • Method and apparatus for detecting chemical binding
    Patent number: 6858148
    Abstract: The method for screening binding between a target binder and potential pharmaceutical chemicals involves sending a solution (preferably an aqueous solution) of the target binder through a conduit to a size exclusion filter, the target binder being too large to pass through the size exclusion filter, and then sending a solution of one or more potential pharmaceutical chemicals (preferably an aqueous solution) through the same conduit to the size exclusion filter after target binder has collected on the filter. The potential pharmaceutical chemicals are small enough to pass through the filter. Afterwards, x-rays are sent from an x-ray source to the size exclusion filter, and if the potential pharmaceutical chemicals form a complex with the target binder, the complex produces an x-ray fluorescence signal having an intensity that indicates that a complex has formed.
    Type: Grant
    Filed: July 16, 2003
    Date of Patent: February 22, 2005
    Assignee: The Regents of the University of California
    Inventors: Benjamin P. Warner, George J. Havrilla, Thomasin C. Miller, Cyndi A. Wells
  • Flow method and apparatus for screening chemicals using micro x-ray fluorescence
    Publication number: 20040017884
    Abstract: Flow method and apparatus for screening chemicals using micro x-ray fluorescence. The invention includes a method and apparatus for screening a mixture of potential pharmaceutical chemicals for binding to at least one target binder. According to the method, after preparing a solution of potential pharmaceutical chemicals with at least one target binder, the solution is flow-separated into at least two separated components. Each component is exposed to an x-ray excitation beam. Any component that emits a detectable x-ray fluorescence signal is isolated.
    Type: Application
    Filed: July 25, 2002
    Publication date: January 29, 2004
    Inventors: George J. Havrilla, Thomasin C. Miller, Benjamin P. Warner, Cris L. Lewis, Cynthia A. Mahan, Cyndi A. Wells