Abstract: A blood pump assembly can include various components such as a housing and a sensor configured to detect one or more characteristics of the blood. In some embodiments, the sensor can be coupled to the housing and can include a sensor membrane configured to deflect in response to a change in a blood parameter (e.g., pressure). The blood pump assembly can include a shield that covers at least a portion of the sensor membrane so as to protect the sensor from damage when the blood pump assembly is inserted through an introducer and navigated through the patient's vasculature and/or when the blood pump assembly is inserted into the heart in a surgical procedure. One or more protective layers can be deposited over the sensor membrane to prevent the sensor membrane from being dissolved through interactions with the patient's blood.

Abstract: A sensor positioning system for a bioprocess engineering unit, wherein a container is provided for receiving a biological medium which, when installed, extends in the axial direction from an upper container end to a lower container end, wherein a holder is provided for holding the container when installed, wherein a sensor is provided for fixing to the container. A positioning aid device for positioning the sensor to be fixed is provided on the container, the positioning aid device has a positioning aid that can be applied directly to or near the container on the holder, which can be brought into different vertical positions and/or circumferential positions relative to at least one reference point provided on the container and/or holder, and the positioning aid device has a technical storage medium or analog print medium with an allocation list.

Abstract: A friction lining assembly having a backing plate and a sheet metal restoring spring fixed thereto, for a partially lined sliding-caliper type disk brake having a brake holder fixed with respect to the vehicle, on which friction lining assemblies arranged on both sides of a brake disk are slidably guided. A housing, which extends over the brake disk and the friction lining assemblies, is slidably mounted on the brake holder. The restoring spring is clamped axially between the brake holder and the friction lining assembly by at least one spring leg and applies a release clearance to the friction lining assembly. The spring leg extends over a hammer-head-shaped claw of the backing plate. The spring leg is plastically deformable in a defined manner under braking actuation as a result of a reduction in the friction-material thickness in order to impose a constantly dimensioned release clearance on the friction lining assembly.

Abstract: The invention relates to a harvesting device (100, 100a, 100b, 100c, 100d) for harvesting a content of a bioreactor bag (102) and to a method for harvesting a content of a bioreactor bag (102). The harvesting device (100, 100a, 100b, 100c, 100d) comprises: a first fixing device (104) for fixing one of the fixing portions (112, 114) to the harvesting device (100, 100a, 100b, 100c, 100d), a second fixing device (106) for fixing the other of the fixing portions (112, 114) to the harvesting device (100, 100a, 100b, 100c, 100d), a base (108), and an adjusting device (110) coupling the first fixing device (104) and/or the second fixing device (106) to the base (108). The adjusting device (110) is configured to selectively allow changing an arrangement of the first fixing portion (112) and/or the second fixing portion (114) relative to the base (108) or fixing the arrangement of the first fixing portion (112) and/or the second fixing portion (114) relative to the base (108).

Abstract: A mixing device with a stirring element includes a container (3) for receiving fluids and/or solids, at least one rotatable stirring element (100) for mixing the fluids and/or solids, at least one bearing element for the support of the stirring element (100). The stirring element (100) has at least one non-permanently magnetized element (118) so that the stirring element (100) can be put in a rotational movement by externally induced reluctance forces. A drive device having at least two pair of coils (208) through which current flows also is provided. A mixing device system includes the mixing device and the drive device. A method also is provided for driving a stirring element in a mixing device.

Abstract: A method is provided for measuring parameters of state of a fluid contained in a container (10, 10?) that has a sensor carrier plate with plural sensors (S01-S10, S01?-S10?). Each sensor has a sensor head in operative contact with the interior of the container (10, 10?) and in operative contact with an external control unit (12). The external control unit (12) receives measurement data generated by the sensor heads of active sensors via their communication link and processes the data. An activation data record (24, 24?) is assigned to each sensor (S01-S10, S01?-S10?) and is recorded in a manner that is accessible for the external control unit (12). The external control unit (12) first accesses the activation data records (24, 24?), then classifies the sensors (S01-S10, S01?-S10?) as activatable or nonactivatable sensors, and subsequently activates only those sensors classified as activatable sensors.

Abstract: A bioreactor for use on a moving platform comprises a bag. According to a first aspect, the bag defines a three-dimensional geometrical shape including at least one lower collecting vertex in which at least two edges of the geometrical shape meet at an angle which is preferably not greater than 90°. The bioreactor further includes at least one port or sensor, preferably a biomass sensor, arranged in the vicinity of the collecting vertex. According to a second aspect, the bag defines a two-dimensional geometrical shape or a three-dimensional geometrical shape. The geometrical shape includes at least one edge, in which at least two faces of the geometrical shape meet at an angle which is preferably not greater than 90°. A longitudinal port/sensor element is arranged along the edge and includes several ports and/or sensors. A bioreactor motion system comprises a moving platform and a bioreactor according to the first or second aspect.

Abstract: A method is provided for measuring status parameters of a fluid contained in a container (10). The container (10) is configured for single use and has a wall on which a sensor-carrier plate is fixed in a fluid-tight manner. The plate carries sensors (S1-S5) that are in operative contact with the internal chamber of the container (10) and connected for data exchange (14) with an external control unit (16) that receives and processes the measurement data from the sensors (S1-S5). The sensor plate also carries a temporarily inactive duplicate (D1-D5) of at least one of the sensors (S1-S5) that is activated if measurement data of the sensor (S1-S5) is classified as atypical in the context of an integrity or plausibility test carried out by the external control unit (16).

Abstract: A partially lined motor-vehicle disk brake of the first caliper type, with a housing including an actuator system as a normal force generator mounted in a slidably guided fashion on a holder, with at least one friction lining which is configured in a hammerhead shape with claws and which is accommodated in a guided fashion with pull-support in holder arms with receptacle recesses in the holder. In order to avoid reversing clicks, the holder is embodied as a closed frame in that holder webs connect the holder arms to one another, and the holder webs are positioned tangentially in front of the housing limbs of the housing. Accordingly, the force flux in the holder is closed, and in the case of pull suspension all the holder arms are nevertheless included in the force flux.

Abstract: A computer system and computer-implemented method are described for controlling and monitoring a process to produce a chemical, pharmaceutical or biotechnological product. The method includes providing a database that stores sets of process parameters to control and monitor a plurality of processes performed in order to produce products, receiving a set of characterizing process parameters that characterize the process, identifying a first set process parameters from the stored sets of process parameters, and controlling and monitoring the process using a successful trajectory that includes a time-based profile of measurements.

Abstract: A friction lining assembly having a backing plate and a sheet metal restoring spring fixed thereto, for a partially lined sliding-caliper type disk brake having a brake holder fixed with respect to the vehicle, on which friction lining assemblies arranged on both sides of a brake disk are slidably guided. A housing, which extends over the brake disk and the friction lining assemblies, is slidably mounted on the brake holder. The restoring spring is clamped axially between the brake holder and the friction lining assembly by at least one spring leg and applies a release clearance to the friction lining assembly. The spring leg extends over a hammer-head- shaped claw of the backing plate. The spring leg is plastically deformable in a defined manner under braking actuation as a result of a reduction in the friction-material thickness in order to impose a constantly dimensioned release clearance on the friction lining assembly.

Abstract: A partially lined motor-vehicle disk brake of the first caliper type, with a housing including an actuator system as a normal force generator mounted in a slidably guided fashion on a holder, with at least one friction lining which is configured in a hammerhead shape with claws and which is accommodated in a guided fashion with pull-support in holder arms with receptacle recesses in the holder. In order to avoid reversing clicks, the holder is embodied as a closed frame in that holder webs connect the holder arms to one another, and the holder webs are positioned tangentially in front of the housing limbs of the housing. Accordingly, the force flux in the holder is closed, and in the case of pull suspension all the holder arms are nevertheless included in the force flux.

Abstract: A method is provided for measuring parameters of state of a fluid contained in a container (10, 10?) that has a sensor carrier plate with plural sensors (S01-S10, S01?-S10?). Each sensor has a sensor head in operative contact with the interior of the container (10, 10?) and in operative contact with an external control unit (12). The external control unit (12) receives measurement data generated by the sensor heads of active sensors via their communication link and processes the data. An activation data record (24, 24?) is assigned to each sensor (S01-S10, S01?-S10?) and is recorded in a manner that is accessible for the external control unit (12). The external control unit (12) first accesses the activation data records (24, 24?), then classifies the sensors (S01-S10, S01?-S10?) as activatable or nonactivatable sensors, and subsequently activates only those sensors classified as activatable sensors.

Abstract: A method is provided for measuring status parameters of a fluid contained in a container (10). The container (10) is configured for single use and has a wall on which a sensor-carrier plate is fixed in a fluid-tight manner. The plate carries sensors (S1-S5) that are in operative contact with the internal chamber of the container (10) and connected for data exchange (14) with an external control unit (16) that receives and processes the measurement data from the sensors (S1-S5). The sensor plate also carries a temporarily inactive duplicate (D1-D5) of at least one of the sensors (S1-S5) that is activated if measurement data of the sensor (S1-S5) is classified as atypical in the context of an integrity or plausibility test carried out by the external control unit (16).

Abstract: The present invention relates to a graphical user interface for arranging music, comprising a first display section showing different tracks and a second display section showing a first channel strip and a second channel strip. Preferably, the second channel strip shows the output routing or the destination of a Send of the first channel strip. The present invention also relates to a process for arranging music using the graphical user interface described above. The process allows that the channel associated with the second channel strip is automatically created when the associated bus is addressed for the first time as a Send or output destination in the first channel strip.

Abstract: A mixing device with a stirring element includes a container (3) for receiving fluids and/or solids, at least one rotatable stirring element (100) for mixing the fluids and/or solids, at least one bearing element for the support of the stirring element (100). The stirring element (100) has at least one non-permanently magnetized element (118) so that the stirring element (100) can be put in a rotational movement by externally induced reluctance forces. A drive device having at least two pair of coils (208) through which current flows also is provided. A mixing device system includes the mixing device and the drive device. A method also is provided for driving a stirring element in a mixing device.

Abstract: A method, electronic device and non-transitory computer readable storage medium for simple and intuitive audio editing of multiple notes at once in an audio editing application. Audio editing can include selecting, inserting, and modifying multiple notes at once with respect to a time interval, including using a brush pattern tool to insert some or all of a stored pattern of notes, and using a time stretch tool to expand, contract, or reverse a set of selected notes.

Abstract: The invention relates to a bioreactor for cultivating cells having a filter bag for separating culture fluid and cells, the filter medium of the filter bag having a degree of swelling of less than 1%. The bioreactor according to the invention is characterized by a high durability of the filter bag thereof.

Abstract: A brake caliper for a disk brake is disclosed. The brake caliper includes a caliper housing defining a bore that extends along a bore axis. A piston of an actuating device is mounted within the bore so as to be movable along the bore axis in an application direction and a return direction. A sealing arrangement is at least partially provided between the piston and the bore. The sealing arrangement includes a sealing ring positioned in a radial groove. A base surface of the groove is formed in the direction of the bore axis and oriented antiparallel with respect to the bore axis such that the groove base surface approaches the bore axis in the application direction.

Abstract: A processor implements methods, systems, and computer program products for detecting transients in an audio file. The method includes dividing the audio file into segments. Transients can be detected both in a full band signal of the audio file and one or more band-pass filtered signals of the audio file. A weight value can be assigned to each transient detected in both the full band signal and band-pass filtered signals. Transients that are below a predetermined threshold value can be eliminated. The time position of each remaining transient is determined and displayed in the audio file.