Abstract: A coating composition useful for coating tablets, such as compressed tablets, caplets, pills, capsules, confectionary or seeds comprises an opacifying amount of crospovidone having an average particle size of less than 10 ?m. Crospovidone having an average particle size of less than 10 ?m is used as opacifier and white pigment in a coating of a coated tablet for replacement of titanium dioxide.

Abstract: The present invention relates to a powder mixture for the preparation of a granulate comprising as constituent at least a filler or at least an active ingredient or both and as granulation aid potassium sodium tartrate tetrahydrate (PST). Optionally constituents of the powder mixture to be granulated are binders, disintegrants and further customary auxiliaries. It was an object of the present invention to provide a powder mixture which can be granulated without adding a liquid but where the water for the granulation is released in-situ from PST. An additional drying step is not required.

Abstract: The present invention relates to a powder mixture for the preparation of a granulate comprising as constituent at least a filler or at least an active ingredient or both and as granulation aid Magnesium diacetate×4H2O and/or Magnesium dichloride×6H2O and/or Magnesium sulfate×7H2O and/or Disodium sulfate xH2O and/or Sodium thiosulfate×5H2O and/or Na3PO4×12H2O and/or Na2HPO4×12H2O/7H2O and/or Sodium acetate×3H2O. Optionally constituents of the powder mixture to be granulated are binders, disintegrants and further customary auxiliaries. It was an object of the present invention to provide a powder mixture which can be granulated without adding a liquid but where the water for the granulation is released in-situ from Magnesium diacetate×4H2O and/or Magnesium dichloride×6H2O and/or Magnesium sulfate×7H2O and/or Disodium sulfate xH2O and/or Sodium thiosulfate×5H2O and/or Na3PO4×12H2O and/or Na2HPO4×12H2O/7H2O and/or Sodium acetate×3H2O. An additional drying step is not required.

Abstract: The present invention relates to a direct tableting auxiliary composition based on lactose powder mixed intimately with a water-soluble polyethylene glycol-polyvinyl alcohol graft copolymeras binder, a lubricants, a colorant and optionally a crosslinked insoluble polyvinylpyrrolidone as tablet disintegrating agent.

Abstract: The present invention relates to a direct tableting auxiliary composition based on lactose powder mixed intimately with a water-soluble polyethylene glycol-polyvinyl alcohol graft copolymeras binder, crosslinked insoluble polyvinylpyrrolidone as tablet disintegrating agent and a lubricant.

Abstract: In order to facilitate product development, such as pharmaceutical product development, a computer implemented method and an apparatus are proposed that enable formulators to develop robust drug formulations in a cost- and time-efficient manner. To start the development process, the user selects the preferred dosage form (e.g., granules, pellets, capsules, tablets etc.), defines a target profile (e.g., amount of active ingredient per unit, size of dosage form, mechanical strength of dosage form, desired release behaviour etc.) and enters key characteristics of the active ingredient (e.g., true density, particle size distribution data, bulk and tapped density, angle of repose, compressibility and compactibility profile etc.). The identity (e.g., chemical name or structure) of the active ingredient is not necessarily disclosed. The apparatus processes the provided data and calculates key parameters of the AI (e.g.

Abstract: Film coating compositions based on a co-processed mixture of a polyvinyl alcohol-polyether graft polymer and polyvinyl alcohol (component A), a N-vinylpyrrolidone-vinyl acetate copolymer (component B) and pigments (component C).

Abstract: Film coating compositions based on a co-processed mixture of a polyvinyl alcohol-polyether graft polymer and polyvinyl alcohol (component A), a N-vinylpyrrolidone-vinyl acetate copolymer (component B) and pigments (component C).