Abstract: One aspect is a system for reception or emission of an electrical signal from or into the human or animal body, comprising at least one insulated electrical conductor; a sleeve-shaped electrode that is electrically connected to the electrical conductor and includes an internal side, an external side, and a channel, wherein the channel defines a longitudinal axis along which the conductor is arranged. According to one embodiment, the conductor extends without interruption along the entire area of the electrode, and the electrode further includes a slit that extends from the internal side to the external side of the electrode and in which the conductor is appropriately arranged in the slit such that the electrode forms a direct durable mechanical and electrical connection to the conductor.

Abstract: One aspect relates to an electrode-electrical conductor system for a medical device including a) one or more electrically insulated wire(s) or cable(s), wherein the electrical insulation includes electrical conductor one or more partial opening(s), which is/are arranged on one side of the wire(s) or cable(s), and b) one or more electrode(s), which is/are mechanically and electrically connected to the wire(s) or cable(s) via the one or more partial opening(s) arranged on one side of the wire(s) or cable(s) by welding, pressing, swaging, adhesives, brazing, soldering and/or dimples. One aspect also relates to a method for preparing such an electrode-electrical conductor system.

Abstract: One aspect relates to a medical electrode, having a conductor, an insulation, which surrounds the conductor at least in some sections over its entire circumference, protrusions in the insulation, electrode segments arranged between the protrusions, and insulating areas arranged between the electrode segments, wherein the electrode segments have steps, wherein the steps engage with the insulating areas.

Abstract: One aspect is a system for reception or emission of an electrical signal from or into the human or animal body, comprising at least one insulated electrical conductor; a sleeve-shaped electrode that is electrically connected to the electrical conductor and includes an internal side, an external side, and a channel, wherein the channel defines a longitudinal axis along which the conductor is arranged. According to one embodiment, the conductor extends without interruption along the entire area of the electrode, and the electrode further includes a slit that extends from the internal side to the external side of the electrode and in which the conductor is appropriately arranged in the slit such that the electrode forms a direct durable mechanical and electrical connection to the conductor.

Abstract: A general method is provided for the production of purified antibodies by separation of an antibody molecule from an antibody variant by chromatographic methods, e.g. to enhance therapeutic efficacy, by for example choosing a specific harvesting time point and/or a specific purification scheme.

Abstract: One aspect relates to a feedthrough system. The feedthrough system includes a feedthrough and a wire. At least a portion of the feedthrough is made of an insulator and at least one area forming an electrically conductive cermet pathway. The cermet pathway may include an electrically conductive metal. The wire may be at least partially connected to the cermet pathway so that the material of the wire forms a joint microstructure with the electrically conductive material in the cermet pathway.

Abstract: One aspect relates to a feedthrough system. The feedthrough system includes a feedthrough and a wire. At least a portion of the feedthrough is made of an insulator and at least one area forming an electrically conductive cermet pathway. The cermet pathway may include an electrically conductive metal. The wire may be at least partially connected to the cermet pathway so that the material of the wire forms a joint microstructure with the electrically conductive material in the cermet pathway.

Abstract: A general method is provided for the production of purified antibodies by separation of an antibody molecule from an antibody variant by chromatographic methods, e.g. to enhance therapeutic efficacy, by for example choosing a specific harvesting time point and/or a specific purification scheme. The current invention thus reports a method for producing an antibody composition comprising an antibody molecule and a variant thereof, comprising the following steps: providing a sample comprising the antibody molecule and a variant thereof, determining the presence of the antibody molecule and/or a variant thereof and/or the ratio of the amount of the antibody molecule or variant thereof to the sum of the amounts of the antibody molecule and the variant thereof, in an aliquot of said sample, determining a subsequent harvesting time point and/or antibody purification scheme on basis of the data obtained before, thereby producing an antibody composition comprising the antibody molecule and a variant thereof.

Abstract: A method of reconfiguring a data unit communication network that comprises bridge nodes is described. Each bridge node comprises two or more ports for receiving and sending data units, a controller for controlling said bridge node and for handling received data units, and a record for associating data unit address information with port identification information. The controller is capable of querying said record for determining which one or more ports to forward a received data unit to.

Abstract: A method of reconfiguring a data unit communication network that comprises bridge nodes is described. Each bridge node comprises two or more ports for receiving and sending data units, a controller for controlling said bridge node and for handling received data units, and a record for associating data unit address information with port identification information. The controller is capable of querying said record for determining which one or more ports to forward a received data unit to.

Abstract: A network bridge comprising two ports for connection to two networks, a spanning tree controller and a wireless bridge link controller for each port. The ports employ an adaptive modulation technique. The wireless bridge link controller is connected to the port to exchange physical layer information with said port. When the port detects a change of its PHY mode, it sets the path cost of the link to a value configured for the new PHY mode and forces the bridge to recalculate its spanning tree. The wireless bridge link controller is also connected to the spanning tree controller. If the bridge detects that it has not received BPDUs for a certain time period and the timer will expire soon, the bridge forces the port, via the wireless bridge link controller, to use a more robust PHY mode.

Abstract: A general method is provided for the production of purified antibodies by separation of an antibody molecule from an antibody variant by chromatographic methods, e.g. to enhance therapeutic efficacy, by for example choosing a specific harvesting time point and/or a specific purification scheme. The current invention thus reports a method for producing an antibody composition comprising an antibody molecule and a variant thereof, comprising the following steps: providing a sample comprising the antibody molecule and a variant thereof, determining the presence of the antibody molecule and/or a variant thereof and/or the ratio of the amount of the antibody molecule or variant thereof to the sum of the amounts of the antibody molecule and the variant thereof, in an aliquot of said sample, determining a subsequent harvesting time point and/or antibody purification scheme on basis of the data obtained before, thereby producing an antibody composition comprising the antibody molecule and a variant thereof.

Abstract: A network bridge comprising two ports for connection to two networks, a spanning tree controller and a wireless bridge link controller for each port. The ports employ an adaptive modulation technique. The wireless bridge link controller is connected to the port to exchange physical layer information with said port. When the port detects a change of its PHY mode, it sets the path cost of the link to a value configured for the new PHY mode and forces the bridge to recalculate its spanning tree. The wireless bridge link controller is also connected to the spanning tree controller. If the bridge detects that it has not received BPDUs for a certain time period and the timer will expire soon, the bridge forces the port, via the wireless bridge link controller, to use a more robust PHY mode.

Abstract: Devices and processes for the quantitative evaluation of the polypeptides contained in a sample of body fluid and markers for recognizing pathological conditions are described. The polypeptides are compared with reference values stored in a data base. These reference values are stored as data records of polypeptides relevant to the condition, which respectively comprise at least some information about the probability of the occurrence and/or the concentration of the polypeptides for a pathological condition in samples of healthy and diseased subjects.

Abstract: Certain embodiments of the invention relate to means and methods for the diagnosis of a renal disease, particularly to differential diagnosis. Renal diseases of particular interest in the context of the invention are IgA-nephropathy, membranous glomerulonephritis (MGN), minimal-change-disease (MCD), focal segemental glomerulosclerosis (FSGS), and diabetic nephropathy.