Patents by Inventor Thorsten Mascher

Thorsten Mascher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Plasmid Copy Number Regulation and Integration
    Publication number: 20230227834
    Abstract: Described herein are materials and methods for user-controlled adjustment of plasmid copy numbers.
    Type: Application
    Filed: June 17, 2021
    Publication date: July 20, 2023
    Inventors: Max Fabian Felle, Christopher SAUER, Karen STETTER, Diana WOLF, Thorsten MASCHER
  • Compositions and methods for screening antibacterial compounds
    Patent number: 7309484
    Abstract: The present invention pertains to compositions and methods used to ascertain if putative antibiotics trigger a cell envelope stress response in bacterial organisms. In one aspect of the invention, three two-component systems are described: LiaR & LiaS (formerly YvqCE); YvcP & YvcQ; and BceR & BceS (formerly YtsAB). These systems, for example, can be used to analyze antibiotics such as vancomycin, bacitracin, nisin, and ramoplanin, which interfere with the lipid II cycle in the cytoplasmic membrane.
    Type: Grant
    Filed: June 23, 2004
    Date of Patent: December 18, 2007
    Assignee: Cornell Research Foundation, Inc.
    Inventors: John D. Helmann, Thorsten Mascher
  • Compositions and methods for screening antibacterial compounds
    Publication number: 20050186653
    Abstract: The present invention pertains to compositions and methods used to ascertain if putative antibiotics trigger a cell envelope stress response in bacterial organisms. In one aspect of the invention, three two-component systems are described: LiaR & LiaS (formerly YvqCE); YvcP & YvcQ; and BceR & BceS (formerly YtsAB). These systems, for example, can be used to analyze antibiotics such as vancomycin, bacitracin, nisin, and ramoplanin, which interfere with the lipid II cycle in the cytoplasmic membrane.
    Type: Application
    Filed: June 23, 2004
    Publication date: August 25, 2005
    Applicant: Cornell Research Foundation, Inc.
    Inventors: John Helmann, Thorsten Mascher