Patents by Inventor Thorsten Verch

Thorsten Verch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LYOSPHERE CRITICAL REAGENT KIT
    Publication number: 20210223262
    Abstract: The present invention provides lyophilized pellets of low concentrations of antibodies in the form of lyospheres. These lyospheres provide pre-measured antibody concentrations suitable for diagnostic and quality control assays.
    Type: Application
    Filed: June 3, 2019
    Publication date: July 22, 2021
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Akhilesh Bhambhani, Thorsten Verch, Morrisa C. Jones, Mary Retzlaff, Jessica R. Sinacola, Silikhone L. Bouaraphan
  • Methods for constructing antibiotic resistance free vaccines
    Patent number: 10426823
    Abstract: The present invention provides Listeria vaccine strains that express a heterologous antigen and a metabolic enzyme, and methods of generating same.
    Type: Grant
    Filed: June 13, 2017
    Date of Patent: October 1, 2019
    Assignee: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Yvonne Paterson, Thorsten Verch
  • METHODS FOR CONSTRUCTING ANTIBIOTIC RESISTANCE FREE VACCINES
    Publication number: 20170281691
    Abstract: The present invention provides Listeria vaccine strains that express a heterologous antigen and a metabolic enzyme, and methods of generating same.
    Type: Application
    Filed: June 13, 2017
    Publication date: October 5, 2017
    Applicant: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Yvonne PATERSON, Thorsten VERCH
  • Methods for constructing antibiotic resistance free vaccines
    Patent number: 9700608
    Abstract: The present invention provides Listeria vaccine strains that express a heterologous antigen and a metabolic enzyme, and methods of generating same.
    Type: Grant
    Filed: October 18, 2016
    Date of Patent: July 11, 2017
    Inventors: Yvonne Paterson, Thorsten Verch
  • METHODS FOR CONSTRUCTING ANTIBIOTIC RESISTANCE FREE VACCINES
    Publication number: 20170028045
    Abstract: The present invention provides Listeria vaccine strains that express a heterologous antigen and a metabolic enzyme, and methods of generating same.
    Type: Application
    Filed: October 18, 2016
    Publication date: February 2, 2017
    Applicant: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Yvonne PATERSON, Thorsten VERCH
  • Methods for constructing antibiotic resistance free vaccines
    Patent number: 9492527
    Abstract: The present invention provides Listeria vaccine strains that express a heterologous antigen and a metabolic enzyme, and methods of generating same.
    Type: Grant
    Filed: November 10, 2014
    Date of Patent: November 15, 2016
    Assignee: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Yvonne Paterson, Thorsten Verch
  • METHODS FOR CONSTRUCTING ANTIBIOTIC RESISTANCE FREE VACCINES
    Publication number: 20150125480
    Abstract: The present invention provides Listeria vaccine strains that express a heterologous antigen and a metabolic enzyme, and methods of generating same.
    Type: Application
    Filed: November 10, 2014
    Publication date: May 7, 2015
    Inventors: YVONNE PATERSON, THORSTEN VERCH
  • Methods for constructing antibiotic resistance free vaccines
    Patent number: 8906664
    Abstract: The present invention provides Listeria vaccine strains that express a heterologous antigen and a metabolic enzyme, and methods of generating same.
    Type: Grant
    Filed: August 15, 2005
    Date of Patent: December 9, 2014
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Yvonne Paterson, Thorsten Verch
  • Use of HE4 for assessment of breast cancers
    Patent number: 8455189
    Abstract: The disclosure relates to use of the HE4 marker to assess breast cancer in a patient. The disclosure also relates to using HE4 and other tumors markers for diagnosis, grading and staging of breast cancers. The disclosure also relates to determining prognosis and treatment effectiveness of a patient who has been diagnosed with breast cancer.
    Type: Grant
    Filed: March 31, 2008
    Date of Patent: June 4, 2013
    Inventors: Jeffrey W. Allard, Thorsten Verch, Curtis Glover
  • Antibiotic resistance free strains and methods for constructing and using same
    Patent number: 7858097
    Abstract: The present invention provides Listeria strains that express a heterologous antigen and a metabolic enzyme, and methods of generating same.
    Type: Grant
    Filed: April 27, 2007
    Date of Patent: December 28, 2010
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Yvonne Paterson, Thorsten Verch
  • Antibiotic resistance free vaccines and methods for constructing and using same
    Patent number: 7855064
    Abstract: The present invention provides Listeria strains that express a heterologous antigen and a metabolic enzyme, and methods of generating same.
    Type: Grant
    Filed: April 16, 2007
    Date of Patent: December 21, 2010
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Yvonne Paterson, Thorsten Verch
  • USE OF HE4 FOR ASSESSMENT OF BREAST CANCERS
    Publication number: 20100311099
    Abstract: The disclosure relates to use of the HE4 marker to assess breast cancer in a patient. The disclosure also relates to using HE4 and other tumors markers for diagnosis, grading and staging of breast cancers. The disclosure also relates to determining prognosis and treatment effectiveness of a patient who has been diagnosed with breast cancer.
    Type: Application
    Filed: March 31, 2008
    Publication date: December 9, 2010
    Inventors: Jeffrey W Allard, Thorsten Verch, Curtis Glover
  • ANTIBIOTIC RESISTANCE FREE LISTERIA STRAINS AND METHODS FOR CONSTRUCTING AND USING SAME
    Publication number: 20100291140
    Abstract: The present invention provides Listeria strains that express a heterologous antigen and a metabolic enzyme, and methods of generating same.
    Type: Application
    Filed: April 27, 2007
    Publication date: November 18, 2010
    Inventors: Yvonne Paterson, Thorsten Verch
  • Antibiotic resistance free vaccines and methods for constructing and using same
    Publication number: 20080131456
    Abstract: The present invention provides Listeria strains that express a heterologous antigen and a metabolic enzyme, and methods of generating same.
    Type: Application
    Filed: April 16, 2007
    Publication date: June 5, 2008
    Inventors: Yvonne Paterson, Thorsten Verch
  • Methods for constructing antibiotic resistance free vaccines
    Publication number: 20060135457
    Abstract: The present invention provides DNA vaccines comprising an antibiotic resistance gene-free plasmid, methods of generating same, and methods for treating a disease agent, comprising same.
    Type: Application
    Filed: August 15, 2005
    Publication date: June 22, 2006
    Inventors: Yvonne Paterson, Thorsten Verch
  • Methods for constructing antibiotic resistance free vaccines
    Publication number: 20060104991
    Abstract: The present invention provides Listeria vaccine strains that express a heterologous antigen and a metabolic enzyme, and methods of generating same.
    Type: Application
    Filed: August 15, 2005
    Publication date: May 18, 2006
    Inventors: Yvonne Paterson, Thorsten Verch