Abstract: An access control device inhibits data transfers on a bus between unauthorized initiator-target pairs. A permission-matrix is maintained that identifies the access permission of each initiator relative to each target. The access device monitors the bus and determines the identification of the initiator and the intended target. If the initiator has the appropriate access rights to the target, the bus communication is permitted to occur, otherwise the communication is blocked, and an error signal is asserted. To provide further security, the identifier of initiators that are local to the access control device are communicated to the access control device via a direct wired connection to each initiator.