Patents by Inventor Thu Nga Bien-Ly

Thu Nga Bien-Ly has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-ApoE antibodies
    Patent number: 11926660
    Abstract: The present disclosure encompasses compositions and methods for effectively treating at least one symptom or sign of Aß plaque or cerebral amyloid angiopathy (CAA) associated symptoms, or for decreasing amyloid plaque load or CAA load. The method comprises administering an effective amount of an anti-ApoE antibody to a mammalian subject, such as to a human.
    Type: Grant
    Filed: August 24, 2021
    Date of Patent: March 12, 2024
    Assignee: Washington University
    Inventors: David Holtzman, Hong Jiang, Thu Nga Bien-Ly, Mark S. Dennis, Jing Guo, Adam P. Silverman, Ryan J. Watts, Yin Zhang
  • ANTI-APOE ANTIBODIES
    Publication number: 20220411485
    Abstract: The present disclosure encompasses compositions and methods for effectively treating at least one symptom or sign of Aß plaque or cerebral amyloid angiopathy (CAA) associated symptoms, or for decreasing amyloid plaque load or CAA load. The method comprises administering an effective amount of an anti-ApoE antibody to a mammalian subject, such as to a human.
    Type: Application
    Filed: August 24, 2021
    Publication date: December 29, 2022
    Inventors: David Holtzman, Hong Jiang, Fan Liao, Thu Nga Bien-Ly, Mark S. Dennis, Jing Guo, Adam P. Silverman, Ryan J. Watts, Yin Zhang
  • Anti-ApoE antibodies
    Patent number: 11124562
    Abstract: The present disclosure encompasses compositions and methods for effectively treating at least one symptom or sign of A plaque or cerebral amyloid angiopathy (CAA) associated symptoms, or for decreasing amyloid plaque load or CAA load. The method comprises administering an effective amount of an anti-ApoE antibody to a mammalian subject, such as to a human.
    Type: Grant
    Filed: October 27, 2017
    Date of Patent: September 21, 2021
    Assignee: Washington University
    Inventors: David Holtzman, Hong Jiang, Fan Liao, Thu Nga Bien-Ly, Mark S. Dennis, Jing Guo, Adam P. Silverman, Ryan J. Watts, Yin Zhang
  • ANTI-APOE ANTIBODIES
    Publication number: 20190270794
    Abstract: The present disclosure encompasses compositions and methods for effectively treating at least one symptom or sign of A plaque or cerebral amyloid angiopathy (CAA) associated symptoms, or for decreasing amyloid plaque load or CAA load. The method comprises administering an effective amount of an anti-ApoE antibody to a mammalian subject, such as to a human.
    Type: Application
    Filed: October 27, 2017
    Publication date: September 5, 2019
    Inventors: David Holtzman, Hong Jiang, Fan Liao, Thu Nga Bien-Ly, Mark S. Dennis, Jing Guo, Adam P. Silverman, Ryan J. Watts, Yin Zhang
  • Antibody specific for apolipoprotein and methods of use thereof
    Patent number: 9102717
    Abstract: The present disclosure provides synthetic antibodies specific for an epitope present on an apolipoprotein E polypeptide. The antibodies are useful in various treatment, diagnostic, and monitoring applications, which are also provided.
    Type: Grant
    Filed: February 25, 2011
    Date of Patent: August 11, 2015
    Assignee: THE J. DAVID GLADSTONE INSTITUTES
    Inventors: Yadong Huang, Qin Xu, Thu Nga Bien-Ly, Karl H. Weisgraber, Ligong Chen, Clare Peters-Libeu
  • Antibody Specific for Apolipoprotein and Methods of Use Thereof
    Publication number: 20130017251
    Abstract: The present disclosure provides synthetic antibodies specific for an epitope present on an apolipoprotein E polypeptide. The antibodies are useful in various treatment, diagnostic, and monitoring applications, which are also provided.
    Type: Application
    Filed: February 25, 2011
    Publication date: January 17, 2013
    Inventors: Yadong Huang, Qin Xu, Thu Nga Bien-Ly, Karl H. Weisgraber, Ligong Chen, Clare Peters-Libeu