Patents by Inventor THUOC LINH TRAN

THUOC LINH TRAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant strain and method for producing active pediocin PA-1
    Patent number: 11807856
    Abstract: A recombinant Pichia pastoris strain which is genetically modified for highly expressing pediocin PA-1 and secreted into a medium so that the pediocin PA-1 is easily collected and purified from the culture medium. The obtained pediocin PA-1 has specific antimicrobial activities against Listeria monocytogenes ATCC 13932 and several other bacteria strains.
    Type: Grant
    Filed: January 1, 2019
    Date of Patent: November 7, 2023
    Assignee: VIET NAM NATIONAL UNIVERSITY HO CHI MINH CITY
    Inventors: Phuong Thao Thi Dang, My Trinh Thi Nguyen, Nghia Hieu Nguyen, Thuoc Linh Tran, Anh Thu Pham Nguyen
  • Mixture of cell extract and method for site-directed cloning
    Patent number: 11198879
    Abstract: The present invention provides novel reagents and a cloning procedure based on homologous recombination for the site-directed cloning of a DNA fragment to a vector at designed site(s). The cloning reagents are made of mixture of extracts from at least two different cell types, preferably a mixture made of extracts from wild-type E. coli and S. cerevisiae. Due to the activity of the mixture of cell extracts, recombination occurs between the 3? and 5?-ends of the target DNA and at the ends of linearized vector, which facilitates in-frame construction of expression vectors.
    Type: Grant
    Filed: October 25, 2018
    Date of Patent: December 14, 2021
    Assignee: VIET NAM NATIONAL UNIVERSITY HO CHI MINH CITY
    Inventors: Phuong Thao Thi Dang, My Trinh Thi Nguyen, Nghia Hieu Nguyen, Thuoc Linh Tran
  • RECOMBINANT PICHIA PASTORIS STRAIN AND METHOD FOR PRODUCING ACTIVE PEDIOCIN PA-1
    Publication number: 20210062200
    Abstract: This invention provides a recombinant Pichia pastoris strain which has been genetically modified for highly expressing pediocin PA-1 and secreting it into the medium so that the pediocin PA-1 can be easily collected and purified from the culture medium. In this invention, we also demonstrated that the obtained pediocin PA-1 had specific antimicrobial activities against Listeria monocytogenes ATCC 13932 and several other bacteria strains. Therefore, pediocin PA-1 produced from this recombinant Pichia pastoris strain has a great potential for the application in food preservation and pharmaceutical industry.
    Type: Application
    Filed: January 1, 2019
    Publication date: March 4, 2021
    Applicant: VIET NAM NATIONAL UNIVERSITY HO CHI MINH CITY
    Inventors: TRINH MY THI NGUYEN, THU ANH PHAM NGUYEN, THUOC LINH TRAN, NGHIA HIEU NGUYEN, THAO PHUONG THI DANG
  • MIXTURE OF CELL EXTRACT AND METHOD FOR SITE-DIRECTED CLONING
    Publication number: 20200131521
    Abstract: The present invention provides novel reagents and a cloning procedure based on homologous recombination for the site-directed cloning of a DNA fragment to a vector at designed site(s). The cloning reagents are made of mixture of extracts from at least two different cell types, preferably a mixture made of extracts from wild-type E. coli and S. Cerevisiae. Due to the activity of the mixture of cell extracts, recombination occurs between the 3? and 5?-ends of the target DNA and at the ends of linearized vector, which facilitates in-frame construction of expression vectors.
    Type: Application
    Filed: October 25, 2018
    Publication date: April 30, 2020
    Applicant: QUYEN HUYNH C/O VIET NAM NATIONAL UNIVERSITY HO CHI MINH CITY
    Inventors: THAO PHUONG THI DANG, TRINH MY THI NGUYEN, NGHIA HIEU NGUYEN, THUOC LINH TRAN