Abstract: The present application provides an agent comprising or consisting of a binding moiety with specificity for a kallikrein protein (for example, PSA or hK2) for use in the treatment of prostate cancer, and a method for the treatment of prostate cancer in a patient, the method comprising the step of administering a therapeutically effective amount of an agent comprising or consisting of a binding moiety with specificity for a kallikrein protein to the patient.

Abstract: The present application provides an agent comprising or consisting of a binding moiety with specificity for a kallikrein protein (for example, PSA or hK2) for use in the treatment of prostate cancer, and a method for the treatment of prostate cancer in a patient, the method comprising the step of administering a therapeutically effective amount of an agent comprising or consisting of a binding moiety with specificity for a kallikrein protein to the patient.

Abstract: A test and measurement apparatus, system, and method for synchronizing an acquisition or triggering system to a specific burst of interest. The subject apparatus and method triggers on varying energy content of a signal qualified by time in the presence of high-frequency input signal bursts, by using an adjustable pulse width envelope detector, disposed in the signal path of the trigger circuitry, as a digital rectifier or to otherwise process and extract an envelope signal. An RF envelope probe having an analog envelope detector among other suitable components is disclosed. A method is implemented for isolating an interval of interest in a signal under test. An envelope detector circuit produces an envelope signal from the signal. Trigger circuitry receives the envelope signal from the envelope detector, and isolates the interval of interesting in the signal under test using the envelope signal.

Abstract: The present application provides an agent comprising or consisting of a binding moiety with specificity for a kallikrein protein (for example, PSA or hK2) for use in the treatment of prostate cancer, and a method for the treatment of prostate cancer in a patient, the method comprising the step of administering a therapeutically effective amount of an agent comprising or consisting of a binding moiety with specificity for a kallikrein protein to the patient.

Abstract: Embodiments of the invention include methods, apparatuses, and systems for automatically identifying a synchronization sub-pattern associated with a test pattern. A test and measurement instrument is triggered in response to a first instance of a trigger pattern in a data stream. A trigger-to-trigger counter begins counting at the time of the first trigger event. The test and measurement instrument is again triggered in response to a second instance of the trigger pattern in the data stream. The count is ended at this time. The count is then compared to a predefined length of the test pattern, and if equal, it is automatically determined that the trigger pattern is the unique synchronization sub-pattern associated with the test pattern.

Abstract: Embodiments of the invention include methods, apparatuses, and systems for automatically identifying a synchronization sub-pattern associated with a test pattern. A test and measurement instrument is triggered in response to a first instance of a trigger pattern in a data stream. A trigger-to-trigger counter begins counting at the time of the first trigger event. The test and measurement instrument is again triggered in response to a second instance of the trigger pattern in the data stream. The count is ended at this time. The count is then compared to a predefined length of the test pattern, and if equal, it is automatically determined that the trigger pattern is the unique synchronization sub-pattern associated with the test pattern.

Abstract: A solder ball contact and a method of making a solder ball contact includes: a first insulating layer with a via formed on an integrated circuit (IC) chip and a metal pad; an under bump metallurgy (UBM) structure disposed within the via and on a portion of the first insulating layer, surrounding the via; a second insulating layer formed on an upper surface of an outer portion of the UBM structure that is centered on the via; and a solder ball that fills the via and is disposed above an upper surface of an inner portion of the UBM structure that contacts the via, in which the UBM structure that underlies the solder ball is of a greater diameter than the solder ball.

Abstract: Combined use transaction cards are disclosed including preferably the functionality of being usable for conducting a financial transaction along with the additional functionality for activation or access to at least one other event. Many types of non-financial events are contemplated such as for access or entry, employee need, student need, and the like. Such cards preferably utilize electronically readable means as may be provided to such cards, such as including magnetic stripes, RFID transponders, OCR text, and one dimensional or two dimensional bar codes.

Abstract: A method may include updating a routing table on a first network element based on a shortest path first calculation in response to a network change event. For each deletion from the routing table, a message may be broadcasted to a second network element adjacent to the first network element indicative of such deletion, the message including a target identifier (TID) associated with such deleted entry, wherein the second network element is configured to invalidate its associated TID address resolution protocol (TARP) cache in response to receiving the message. For each deletion from the routing table, a local TARP cache of the first network element may be searched to determine if an entry exists in the local TARP cache mapping the TID associated with such entry to a NASP associated with such entry. The local TARP cache may be invalidated in response to determining that the entry exists.

Abstract: A solder ball contact and a method of making a solder ball contact includes: a first insulating layer with a via formed on an integrated circuit (IC) chip and a metal pad; an under bump metallurgy (UBM) structure disposed within the via and on a portion of the first insulating layer, surrounding the via; a second insulating layer formed on an upper surface of an outer portion of the UBM structure that is centered on the via; and a solder ball that fills the via and is disposed above an upper surface of an inner portion of the UBM structure that contacts the via, in which the UBM structure that underlies the solder ball is of a greater diameter than the solder ball.

Abstract: A solder ball contact and a method of making a solder ball contact includes: a first insulating layer with a via formed on an integrated circuit (IC) chip and a metal pad; an under bump metallurgy (UBM) structure disposed within the via and on a portion of the first insulating layer, surrounding the via; a second insulating layer formed on an upper surface of an outer portion of the UBM structure that is centered on the via; and a solder ball that fills the via and is disposed above an upper surface of an inner portion of the UBM structure that contacts the via, in which the UBM structure that underlies the solder ball is of a greater diameter than the solder ball.

Abstract: A test and measurement instrument including an input configured to receive a signal and output digitized data; a memory configured to store reference digitized data including a reference sequence; a pattern detector configured to detect the reference sequence in the digitized data and generate a synchronization signal in response; a memory controller configured to cause the memory to output the reference digitized data in response to the synchronization signal; and a comparator configured to compare the reference digitized data output from the memory to the digitized data.

Abstract: The present invention pertains to certain compounds of Formula (Ia) and pharmaceutical compositions thereof that modulate the activity of the 5-HT2A serotonin receptor. Compounds and pharmaceutical compositions thereof are directed to methods useful in the treatment of platelet aggreagation, coronary artery disease, myocardial infarction, transient ischemic attack, angina, stroke, atrial fibrillation, blood clot formation, asthma or symptoms thereof, agitation or a symptom thereof, behavioral disorders, drug induced psychosis, excitative psychosis, Gilles de la Tourette's syndrome, manic disorder, organic or NOS psychosis, psychotic disorder, psychosis, acute schizophrenia, chronic schizophrenia, NOS schizophrenia and related disorders, and sleep disorders, sleep disorders, diabetic-related disorders, progressive multifocal leukoencephalopathy and the like.

Abstract: A solder ball contact and a method of making a solder ball contact includes: a first insulating layer with a via formed on an integrated circuit (IC) chip and a metal pad; an under bump metallurgy (UBM) structure disposed within the via and on a portion of the first insulating layer, surrounding the via; a second insulating layer formed on an upper surface of an outer portion of the UBM structure that is centered on the via; and a solder ball that fills the via and is disposed above an upper surface of an inner portion of the UBM structure that contacts the via, in which the UBM structure that underlies the solder ball is of a greater diameter than the solder ball.

Abstract: The present invention provides novel compounds and pharmaceutical compositions thereof, as well as methods for using the compounds and pharmaceutical compositions for treating tumors. Examples of specific tumor types that the compounds may be used to treat include, but are not limited to sarcomas, melanomas, neuroblastomas, carcinomas (including but not limited to lung, renal cell, ovarian, liver, bladder, and pancreatic carcinomas), and mesotheliomas.

Abstract: A method may include updating a routing table on a first network element based on a shortest path first calculation in response to a network change event. For each deletion from the routing table, a message may be broadcasted to a second network element adjacent to the first network element indicative of such deletion, the message including a target identifier (TID) associated with such deleted entry, wherein the second network element is configured to invalidate its associated TID address resolution protocol (TARP) cache in response to receiving the message. For each deletion from the routing table, a local TARP cache of the first network element may be searched to determine if an entry exists in the local TARP cache mapping the TID associated with such entry to a NASP associated with such entry. The local TARP cache may be invalidated in response to determining that the entry exists.

Abstract: Systems and methods are provided for evaluating an effect of a simulated communication network to media data. The method includes encoding media data to produce a plurality of packets, each packet being associated with a packet index number, a packet size and a packet transmission time. The packet index number, packet size and packet transmission time for each of the plurality of packets can be input to a communication network simulator to create trace packets corresponding to the plurality of packets. The communication network simulator output indicates at least one effect of the simulated communication network to input trace packets.

Abstract: A system and method for utilizing a highly secure two-dimensional matrix code on a mobile communications display includes a mobile communications device having a visible display, and a means for creating a highly secure two-dimensional matrix code representing selected data. Means are provided for selectively transmitting the highly secure two-dimensional matrix code, from the means for creating it to the mobile communications device. The highly secure two-dimensional matrix code is then displayed on the visible display of the mobile communications device. Upon reading the code, a transaction is facilitated.

Abstract: Methods and systems are disclosed for monitoring vehicular traffic congestion through the use of inter-vehicle communication and traffic chain counters. Data packets including counter, vehicle identification, direction, location, and speed information are transmitted between vehicles via short-range wireless communications. A receiving vehicle edits a data packet if the data packet reflects that the receiving vehicle has not yet edited the packet and is traveling in substantially the same direction as the vehicle which transmitted the packet to the receiving vehicle. If a receiving vehicle is the last vehicle to edit a packet, the receiving vehicle transmits a reporting packet to a traffic monitoring server via long-range wireless communications.

Abstract: A test and measurement instrument including an input configured to receive a signal and output digitized data; a memory configured to store reference digitized data including a reference sequence; a pattern detector configured to detect the reference sequence in the digitized data and generate a synchronization signal in response; a memory controller configured to cause the memory to output the reference digitized data in response to the synchronization signal; and a comparator configured to compare the reference digitized data output from the memory to the digitized data.