Abstract: A method of operation of a compute system includes: generating a skin segmentation including a non-skin region and a skin prediction based on a patient image; generating a body part segmentation based on the patient image; generating a cropped image based on the skin segmentation and the body part segmentation with the cropped image includes the non-skin region based on the skin prediction; generating a eczema segmentation based on the cropped image and the skin prediction; generating intermediate scores for erythema, papulation, lichenification, and excoriation for the cropped image; and generating a full body EASI score based on the eczema segmentation and the intermediate scores for displaying on a device to assist in diagnosis.

Abstract: A method of operation of a compute system includes: generating a skin segmentation including a non-skin region and a skin prediction based on a patient image; generating a body part segmentation based on the patient image; generating a cropped image based on the skin segmentation and the body part segmentation with the cropped image includes the non-skin region based on the skin prediction; generating a lesion segmentation based on the cropped image and the skin prediction; generating intermediate scores for erythema, induration, desquamation for the cropped image; and generating a full body severity score based on the lesion segmentation and the intermediate scores for displaying on a device to assist in diagnosis.

Abstract: An electronic device may include baseband circuitry coupled to antennas over a communication path that includes signal paths on a first substrate, a second substrate, and a third substrate. The antennas may be disposed on the third substrate. A wireless connector may couple the paths on the third substrate to the paths on the second substrate. The wireless connector may include a first transceiver and first antenna on the third substrate and a second transceiver and second antenna on the second substrate. The wireless connector may include one or more dielectric layers disposed between the first antenna and the second antenna. The layers may form a smooth impedance transition between the first antenna and the second antenna. The layers may include one or two angled layers that redirect wireless signals between the first and second antennas to allow the first and second substrates to be offset within the device.

Abstract: Described herein are robotic platforms and associated features that may have applicability in a wide variety of applications and industries, but that may have particular applicability in automotive testing and testing of vehicles having autonomous or semi-autonomous driving features. Robotic platforms may include a low-profile chassis, one or more rotational elements coupled to one or more drive motors and supported within the chassis, and a control system coupled to and controlling the drive motor(s). Also disclosed are suspension systems that may maintain the chassis of a robotic platform above the ground in use but that allows the chassis to ground out when subject to a pre-determined load, thereby spreading the load across the chassis.

Abstract: The present disclosure relates to cytochrome P450 monooxygenases capable of oxidizing a monoterpenoid indole alkaloid (MIA) substrate and methods and uses thereof. The substrate may be a camptothecinoid, an evodiaminoid or an ellipticinoid. The disclosure further relates to method of producing hydroxylated monoterpenoid indole alkaloids, as well as derivatives and analogues of the produced hydroxylated monoterpenoid indole alkaloids. Pharmaceutical compositions comprising the hydroxylated monoterpenoid indole alkaloid derivatives are also provided.

Abstract: Method of analysis text message syntactically and by content, which entails: step 1; Split syntaxes (made available to subscribers by the network operator) into tokens to store in a Syntax Trie; step 2. Pre-process an incoming text from a subscriber; step 3. Split the text (pre-processed in Step 2) into tokens; step 4. Look up paths that include the tokens (obtained in Step 3) in the Syntax Trie (initialized in Step 1); step 5: Return the look-up result, which is the path in the Syntax Trie that best reflects the user intent.

Abstract: Neuropeptide FF receptor modulators based on a proline scaffold are provided which offer NPFF receptor potencies in the nanomolar range and antagonistic selectivity for the NPFF1 receptor. Methods, compounds and compositions for modulating the function of neuropeptide FF receptors are provided for pharmacotherapies capable of influencing conditions or disorders affected by the neuropeptide FF receptors.

Abstract: A method of operation of a compute system includes: generating a skin segmentation including a non-skin region and a skin prediction based on a patient image; generating a body part segmentation based on the patient image; generating a cropped image based on the skin segmentation and the body part segmentation with the cropped image includes the non-skin region based on the skin prediction; generating a psoriasis segmentation based on the cropped image and the skin prediction; generating intermediate scores for erythema, induration, desquamation for the cropped image; and generating a full body PASI score based a psoriasis segmentation and the intermediate scores on the for displaying on a device to assist in diagnosis.

Abstract: Neuropeptide FF receptor modulators based on a proline scaffold are provided which offer NPFF receptor potencies in the nanomolar range and antagonistic selectivity for the NPFF1 receptor. Methods, compounds and compositions for modulating the function of neuropeptide FF receptors are provided for pharmacotherapies capable of influencing conditions or disorders affected by the neuropeptide FF receptors.

Abstract: Handling user-demanded privacy controls over data of an electronic document collaboration system. A storage facility is configured to store content objects and associated metadata that pertains to the content objects. A user raises a privacy action request that comprises a demand to change how certain content objects that contain personally identifiable information (PII) of the user are handled. A plurality of content objects are classified using a PII classifier that is trained using synthetically-generated training set entries where, rather than reading actual contents from electronic documents of the collaboration system to generate training set entries, instead, the training set entries are generated using words that are randomly selected from a repository of natural language words. When PII corresponding to the user who raised the privacy action request is discovered in content objects, then the content management system modifies those content objects and/or its metadata in accordance with the demand.

Abstract: A method of predicting an output of oil and gas production in a hydrocarbon reservoir of a current and future producing well using a neural network model, includes receiving a data set comprising a plurality of parameters of the hydrocarbon reservoir at a wellsite. The method also includes using the data set to generate a plurality of simulation curves of the hydrocarbon reservoir, each parameter of the plurality of parameters has a range, and the range is adjustable, and the wellsite includes a wellbore penetrating a subterranean formation to extract reserves from the hydrocarbon reservoir. The method also includes performing a simulation, based on the range of each said parameter of the plurality of parameters, of the hydrocarbon reservoir. The method also includes downloading the plurality of simulation curves into a local server to prepare training data for training the neural network model.

Abstract: Neuropeptide FF receptor modulators based on a proline scaffold are provided which offer NPFF receptor potencies in the nanomolar range and antagonistic selectivity for the NPFF1 receptor. Methods, compounds and compositions for modulating the function of neuropeptide FF receptors are provided for pharmacotherapies capable of influencing conditions or disorders affected by the neuropeptide FF receptors.

Abstract: A wireless communication system may include an electronic device having an antenna element. The antenna element may convey radio-frequency signals greater than 10 GHz across a dielectric housing wall. A dielectric matching structure may be interposed between the antenna element and the dielectric housing wall. The wireless communication system may include external equipment having an antenna element communicatively coupled to the electronic device antenna element to convey firmware testing, debugging, restore, and/or other data via a near-field wireless communication link. The external equipment may be configured to receive the electronic device at an opening. A dielectric matching structure may be provided at the external equipment between the dielectric housing wall and the external equipment antenna element. The interior surface of the dielectric housing wall may have planar, convex, or concave portions.

Abstract: An intraocular device that includes a fluid lens is provided. The fluid lens has an anterior side and posterior side that can be coupled together to form a closed cavity therebetween that can be filled with a liquid material. A channel can be formed in the posterior side that is configured to receive a joining substance that bonds the anterior side to the posterior side and inhibit the unintended spread of the joining substance. A syringe can be extended through a port in the fluid lens to flow liquid material into the closed cavity. Subsequently, a plug can be inserted into the port to prevent the escape of the liquid material.

Abstract: A nanostructure for isolating or concentrating extracellular vesicles or a pathogen, includes a transferrin family protein linked on magnetic nanoparticles. The nanostructure includes a transferrin family protein, and thus has selectivity for a pathogen or extracellular vesicles capable of binding to the transferrin family protein, and the synthesized nanostructure is positively (+) charged. The nanostructure includes magnetic nanoparticles, a target material is easily and simply isolated from other materials by magnetism when a magnetic field is applied.

Abstract: A coating for an expandable portion of a catheter comprising a lipophilic matrix and a plurality of micro-reservoirs dispersed in the lipophilic matrix is disclosed. The plurality of micro-reservoirs comprises an active agent. A coating formulation and a method for forming the coating are also disclosed. A catheter comprising the coating on the expandable portion and a method for treating a condition are also provided.

Abstract: Neuropeptide FF receptor modulators based on a proline scaffold are provided which offer NPFF receptor potencies in the nanomolar range and antagonistic selectivity for the NPFF1 receptor. Methods, compounds and compositions for modulating the function of neuropeptide FF receptors are provided for pharmacotherapies capable of influencing conditions or disorders affected by the neuropeptide FF receptors.

Abstract: A coating for an expandable portion of a catheter comprising a lipophilic matrix and a plurality of micro-reservoirs dispersed in the lipophilic matrix is disclosed. The plurality of micro-reservoirs comprises an active agent. A coating formulation and a method for forming the coating are also disclosed. A catheter comprising the coating on the expandable portion and a method for treating a condition are also provided.

Abstract: Described herein are methods, compositions and processes related to a microbial-based biosensor system for the detection of small molecules and analytes based on an analyte-responsive transcription factor-DNA binding mechanism with either a ratiometric fluorescent output through Förster resonance energy transfer (FRET) or a redox sensor output for the quantification of the target analyte with high sensitivity.