Patents by Inventor Thuytien N. Nguyen

Thuytien N. Nguyen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Monolithic matrix transdermal delivery system for administering molsidomine
    Patent number: 5962013
    Abstract: This invention provides monolithic matrix formulations for transdermal administration of molsidomine. The device includes a copolymer of 2-ethylhexyl acrylate, 2-hydroxyethylmethacrylate, and methacrylic acid. The invention also provides transdermal devices having a monolithic matrix made using such a formulation in combination with an active ingredient and a vehicle or vehicle formulation.
    Type: Grant
    Filed: August 4, 1998
    Date of Patent: October 5, 1999
    Assignee: Cygnus, Inc.
    Inventors: Ooi Wong, Thuytien N. Nguyen
  • Monolithic matrix transdermal delivery system for delivering ketorolac tromethamine
    Patent number: 5804214
    Abstract: This invention provides monolithic matrix formulations for transdermal administration of ketorolac tromethamine. The device includes a copolymer of 2-ethylhexyl acrylate, 2-hydroxyethylmethacrylate, and methacrylic acid. This invention also provides transdermal devices having a monolithic matrix made using such a formulation in combination with an active ingredient and a vehicle or vehicle formulation.
    Type: Grant
    Filed: March 7, 1996
    Date of Patent: September 8, 1998
    Assignee: Cygnus, Inc.
    Inventors: Ooi Wong, Thuytien N. Nguyen
  • Enhancement of transdermal drug delivery using monoalkyl phosphates and other absorption promoters
    Patent number: 5358715
    Abstract: Pharmaceutical formulations, transdermal drug delivery devices, and methods of drug delivery using the formulations and devices of the invention are disclosed which make it possible to enhance the rate of transdermal drug delivery of pharmaceutically active compounds and in particular molsidomine. The rate of drug delivery is increased by using absorption promoters which include monoalkyl phosphates and salts thereof alone or in combination with other absorption promoters such as polyhydroxyl esters, longchain fatty acids, polyhydroxyl alcohols and terpenes. Particular combinations of monoalkyl phosphates with one or more additional absorption promoters provides synergistic effects with respect to enhancing the rate of drug delivery of certain pharmaceutically active drugs such as molsidomine.
    Type: Grant
    Filed: December 8, 1993
    Date of Patent: October 25, 1994
    Assignee: Cygnus Therapeutic Systems
    Inventors: Ooi Wong, Thuytien N. Nguyen
  • Enhancement of transdermal drug delivery using monoalkyl phosphates and other absorption promoters
    Patent number: 5308625
    Abstract: Pharmaceutical formulations, transdermal drug delivery devices, and methods of drug delivery using the formulations and devices of the invention are disclosed which make it possible to enhance the rate of transdermal drug delivery of pharmaceutically active compounds and in particular molsidomine. The rate of drug delivery is increased by using absorption promoters which include monoalkyl phosphates and salts thereof alone or in combination with other absorption promoters such as polyhydroxyl esters, longchain fatty acids, polyhydroxyl alcohols and terpenes. Particular combinations of monoalkyl phosphates with one or more additional absorption promoters provides synergistic effects with respect to enhancing the rate of drug delivery of certain pharmaceutically active drugs such as molsidomine.
    Type: Grant
    Filed: September 2, 1992
    Date of Patent: May 3, 1994
    Assignee: Cygnus Therapeutic Systems
    Inventors: Ooi Wong, Thuytien N. Nguyen