Patents by Inventor Tiago Gil Oliveira

Tiago Gil Oliveira has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modulation of phospholipase D for the treatment of neurodegenerative disorders
    Patent number: 9267122
    Abstract: The present invention relates to methods of treating neurodegenerative diseases comprising administering, to a subject in need of such treatment, one or more agent that inhibits or reduces the action, including the catalytic activity, of an enzyme of the phospholipase D family, such as phospholipase D1 and/or phospholipase D2. The present invention also relates to cell-based assays which may be used to identify agents that inhibit or reduce the activity of enzymes of the phospholipase D family and that may be used in the treatment of neurodegenerative diseases.
    Type: Grant
    Filed: November 28, 2011
    Date of Patent: February 23, 2016
    Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    Inventors: Gilbert DiPaolo, Tae-Wan Kim, Tiago Gil Oliveira
  • Modulation of Phospholipase D for the Treatment of the Acute and Chronic Effects of Ethanol
    Publication number: 20120302604
    Abstract: The present invention relates to methods of decreasing the negative effects of alcohol on behavior as well as inhibiting the toxic effects of alcohol, comprising administering, to a subject, an effective amount of an inhibitor of phospholipase D.
    Type: Application
    Filed: January 26, 2012
    Publication date: November 29, 2012
    Inventors: Gilbert DiPaolo, Tiago Gil Oliveira, Samuel G. Frere, Markus Wenk, Robin Chan
  • MODULATION OF PHOSPHOLIPASE D FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS
    Publication number: 20120178719
    Abstract: The present invention relates to methods of treating neurodegenerative diseases comprising administering, to a subject in need of such treatment, one or more agent that inhibits or reduces the action, including the catalytic activity, of an enzyme of the phospholipase D family, such as phospholipase D1 and/or phospholipase D2. The present invention also relates to cell-based assays which may be used to identify agents that inhibit or reduce the activity of enzymes of the phospholipase D family and that may be used in the treatment of neurodegenerative diseases.
    Type: Application
    Filed: November 28, 2011
    Publication date: July 12, 2012
    Applicant: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    Inventors: Gilbert DiPaolo, Tae-Wan Kim, Tiago Gil Oliveira