Abstract: Embodiments of the present disclosure relate to multimedia processing method, apparatus, device and medium, wherein the method includes: presenting a first multimedia interface comprising first content; receiving an interface switching request of a user in the first multimedia interface; and switching from the first multimedia interface currently presented to a second multimedia interface, and presenting second content in the second multimedia interface, wherein the first content comprises the second content and other content associated with the second content, and the second content comprises a target audio and a target subtitle corresponding to the target audio.

Abstract: Suppressing a hand gesture upon detecting peripheral events on a peripheral device includes determining a first hand pose for a first hand a second hand pose for a second hand in response to a detected peripheral device peripheral event, determining, based on the first hand pose and the second hand pose, at least one hand of the first hand and the second hand in a peripheral use mode, detecting an input gesture from a hand of the at least one hand determined to be in the peripheral use mode, and rejecting the input gesture by a user input pipeline in accordance with the determination that the hand is in the peripheral use mode. The presence of a peripheral device is confirmed by activating a computer vision system in response to determining that a peripheral use condition is satisfied.

Abstract: This application provides a secure boot apparatus and method. A control circuit in the secure boot apparatus can obtain boot code in a nonvolatile memory by using a non-programmable circuit, and verify the boot code by using a root of trust. In this way, even if the root of trust is not built in a processor, the verification on the boot code can be implemented by using the control circuit. This effectively reduces dependency of a secure boot process on processor performance. In addition, because the non-programmable circuit can be respectively coupled to the control circuit and the nonvolatile memory through two interfaces of different types, a requirement for the secure boot process on an interface protocol type of the control circuit is reduced, and application flexibility of a secure boot solution is improved.

Abstract: Provided is engineered microorganisms expressing acetoacetyl-CoA reductase variants and a method for improving the yield of PHA. Compared with the wild-type acetoacetyl-CoA reductase represented by SEQ ID NO. 31, the variant has one or more of the following mutations: (1) mutation of valine at position 141 to isoleucine or leucine; (2) mutation of methionine at position 12 to threonine, serine, alanine, leucine, lysine or isoleucine; (3) mutation of isoleucine at position 194 to valine, leucine or methionine; (4) mutation of glutamic acid at position 42 to lysine, glutamine, leucine, aspartic acid, proline, threonine, asparagine, or histidine; and (5) mutation of phenylalanine at position 55 to valine, alanine or isoleucine. The variants and their coding genes can promote the synthesis and accumulation of PHA by the strain and increase the yield of PHA.

Abstract: Conducting coatings disposed on a metal member. The conducting coatings may have a desired texture and provide homoepitaxial or heteroepitaxial coating of an electrodeposited layer. A conducting coating may be formed by applying a shear force during deposition of the conducting coating. The conducting coatings may be used in anodes of various electrochemical devices. A conducting coating, which may be part of an electrochemical device, may have an electrochemically deposited layer disposed on at least a portion of a surface of the conducting coating. The electrochemically deposited layer may be reversibly electrochemically deposited.

Abstract: Conducting coatings disposed on a metal member. The conducting coatings may have a desired texture and provide homoepitaxial or heteroepitaxial coating of an electrodeposited layer. A conducting coating may be formed by applying a shear force during deposition of the conducting coating. The conducting coatings may be used in anodes of various electrochemical devices. A conducting coating, which may be part of an electrochemical device, may have an electrochemically deposited layer disposed on at least a portion of a surface of the conducting coating. The electrochemically deposited layer may be reversibly electrochemically deposited.

Abstract: A lock structure and a cooking appliance are provided. The lock structure has a fixing member and a locking assembly. The locking assembly has a bearing member, a mount connected to the bearing member, a driving member, a first elastic member and a locking member. The bearing member is detachably connected to a surface. At least a portion of the driving member is provided within the mount. A first end of the first elastic member is connected to the driving member. The locking member is connected to a second end of the first elastic member. The locking member is capable of moving relative to the mount under the driving of the driving member and the first elastic member, and is locked to or separated from the fixing member.

Abstract: A lock structure and a cooking appliance are provided. The locking structure a fixing member and a locking assembly. The locking assembly has a mount, a driving member, a first elastic member and a locking member. At least a portion of the driving member is provided within the mount. A first end of the first elastic member is connected to the driving member. The locking member is connected to a second end of the first elastic member. The locking member is capable of moving relative to the mount under the driving of the driving member and the first elastic member, and is locked to or separated from the fixing member.

Abstract: The present invention relates to a multi-target tyrosine kinase inhibitor, which is a compound having protein kinase inhibitory activity as shown in formula (I). The compound is metabolized into an active small molecule td32-4 that inhibits tumor growth in vivo, so as to achieve the anti-tumor effect. Compared with td32-4, the compound of the present invention has significantly improved solubility and oral bioavailability, and shows strong anti-tumor activity in animal in vivo experiments. The present invention relates to a synthetic method for the compound of formula (I) and an application thereof in the field of pharmaceuticals.

Abstract: Conducting coatings disposed on a metal member. The conducting coatings may have a desired texture and provide homoepitaxial or heteroepitaxial coating of an electrodeposited layer. A conducting coating may be formed by applying a shear force during deposition of the conducting coating. The conducting coatings may be used in anodes of various electrochemical devices. A conducting coating, which may be part of an electrochemical device, may have an electrochemically deposited layer disposed on at least a portion of a surface of the conducting coating. The electrochemically deposited layer may be reversibly electrochemically deposited.

Abstract: Provided in the present invention are a crystal form of a small molecule immune compound, a preparation method therefor and a pharmaceutical composition containing the same; the compound is (3Z,6Z)-3-[((E)-3-(5-tert-butyl)-1H-imidazolyl-4-yl)methylene]-6-((E)-3-(3-fluorophenyl)-2-propenylene)piperazine-2,5-dione; the crystal form thereof has stable morphology, good chemical stability, high temperature resistance, and is used for treating hyperproliferative diseases. The structural formula of the compound is as shown in formula (I).

Abstract: Provided in the present invention are a crystal form of a small molecule immune compound, a preparation method therefor and a pharmaceutical composition containing the same; the compound is (3Z,6Z)-3-[((E)-3-(5-tert-butyl)-1H-imidazolyl-4-yl)methylene]-6-((E)-3-(3-fluorophenyl)-2-propenylene)piperazine-2,5-dione; the crystal form thereof has stable morphology, good chemical stability, high temperature resistance, and is used for treating hyperproliferative diseases. The structural formula of the compound is as shown in formula (I).

Abstract: A restocking system includes a first compartment for storing consumable items; a restocking suggestion unit configured to receive restocking suggestions from a remotely located server; an output interface configured to output the restocking suggestions to a user; and a first hardware button located in an interior of the first compartment. The first hardware button is configured to: after a first restocking suggestion is output by the output interface, prompt the user to provide a confirmation input regarding the first restocking suggestion; send a respective confirmation signal to the remotely located server if the first hardware button is activated by the user within a preset time window after the first restocking suggestion is output; and send a respective rejection signal to the remotely located server if the first hardware button is not activated within the preset time window. A corresponding restocking method is also disclosed.

Abstract: A restocking system includes a first compartment for storing consumable items; a restocking suggestion unit configured to receive restocking suggestions from a remotely located server; an output interface configured to output the restocking suggestions to a user; and a first hardware button located in an interior of the first compartment. The first hardware button is configured to: after a first restocking suggestion is output by the output interface, prompt the user to provide a confirmation input regarding the first restocking suggestion; send a respective confirmation signal to the remotely located server if the first hardware button is activated by the user within a preset time window after the first restocking suggestion is output; and send a respective rejection signal to the remotely located server if the first hardware button is not activated within the preset time window. A corresponding restocking method is also disclosed.

Abstract: An interaction method is presented for interference coordination information between base stations, a method for mitigating cross-link interference between base stations, and a base station using abovementioned methods. The interaction method for interference coordination information between base stations comprises: determining a predetermined beam setup of a base station; establishing a beam index indicating each beam in the predetermined beam setup and its corresponding status; and transmitting the beam index to other base stations. The method for mitigating cross-link interference between base stations comprises: receiving beam-associated interference coordination information from other base stations; determining, based on the interference coordination information, beam-associated interference status information; and adjusting, based on the interference status information, a power and/or a modulation coding scheme of each beam.

Abstract: Provided are a new tubulin inhibitor and applications thereof, the tubulin inhibitor being a series of compounds based on substituted heterocyclic skeletons, targeting the colchicine binding sites of tubulin. The structure is: Formula (I), wherein: formula (A), n independently expresses an integer between 0 and 5, the condition being that n?5, A represents mono- or poly-substituted groups, the groups being selected from the group consisting of H, C1-C20 amide group, C1-C20 acyloxy group, C1-C20 alkanoyl group, C1-C20 alkoxycarbonyl group, C1-C20 alkoxy group, C1-C20 alkylamino group, C1-C20 alkylcarboxyamino group, aroyl group, aralkanoyl group, carboxyl group, cyano group, halogen group, hydroxyl group, nitro group and methylthienyl group.

Abstract: A voice-assisted restocking system includes: a first compartment for storing a plurality of consumable items; a restocking suggestion unit that is configured to receive voice-based restocking suggestions from a remotely located digital assistant server over a network communication interface; a voice output interface configured to output the voice-based restocking suggestions to a user; and a first hardware button that is located in the interior of the first compartment, wherein the first hardware button is configured to: after a first voice-based restocking suggestion from the digital assistant is output by the voice output interface, prompt the user to provide a confirmation input regarding the first voice-based restocking suggestion; and send a respective confirmation signal to the remotely located digital assistant when the first hardware button is activated by the user. A corresponding voice-assisted restocking method is also disclosed.

Abstract: A method includes: generating a first nutritional plan for a first user to be implemented in a first time period; monitoring events relevant to real-world implementation of the first nutritional plan by the first user; detecting, via a first kitchen appliance, a first user action associated with the first kitchen appliance; determining a first deviation between the first nutritional plan and a projected nutritional outcome derived based on the monitored events that occurred during a first portion of the first time period up to detection of the first user action; in accordance with the first deviation, revising the first nutritional plan to obtain a second nutritional plan to be implemented in a remainder portion of the first time period; generating a first suggestion regarding a second user action associated with the first kitchen appliance based on the second nutritional plan; and outputting the first suggestion via the first kitchen appliance.

Abstract: A voice-assisted restocking system includes: a first compartment for storing a plurality of consumable items; a restocking suggestion unit that is configured to receive voice-based restocking suggestions from a remotely located digital assistant server over a network communication interface; a voice output interface configured to output the voice-based restocking suggestions to a user; and a first hardware button that is located in the interior of the first compartment, wherein the first hardware button is configured to: after a first voice-based restocking suggestion from the digital assistant is output by the voice output interface, prompt the user to provide a confirmation input regarding the first voice-based restocking suggestion; and send a respective confirmation signal to the remotely located digital assistant when the first hardware button is activated by the user. A corresponding voice-assisted restocking method is also disclosed.

Abstract: Provided are a new tubulin inhibitor and applications thereof, the tubulin inhibitor being a series of compounds based on substituted heterocyclic skeletons, targeting the colchicine binding sites of tubulin. The structure is: Formula (I), wherein: formula (A), n independently expresses an integer between 0 and 5, the condition being that n?5, A represents mono- or poly-substituted groups, the groups being selected from the group consisting of H, C1-C20 amide group, C1-C20 acyloxy group, C1-C20 alkanoyl group, C1-C20 alkoxycarbonyl group, C1-C20 alkoxy group, C1-C20 alkylamino group, C1-C20 alkylcarboxyamino group, aroyl group, aralkanoyl group, carboxyl group, cyano group, halogen group, hydroxyl group, nitro group and methylthienyl group.