Abstract: A system and method for gene editing by using an engineered cell are provided. The system includes the engineered cell embedded with a synthetic protein receptor and a target cell. The engineered cell contains a CRISPR/CasRx system and a sgRNA gene sequence. The synthetic protein receptor includes an extracellular target cell recognition domain, a native Notch core domain, an intramembranous hydrolyzable polypeptide and effectors. The extracellular target cell recognition domain can recognize antigen molecules on the target cell surface; and the effectors act as transcription factors for CasRx enzyme and sgRNAs. CasRx and gRNA are expressed in the engineered cell for gene editing to edit mRNA of the target cell. In this way, the application range of the engineered cell is expanded, the pertinence and specificity of gene editing are improved, the off-target effect is reduced, the collective non-specific reaction is reduced, and the safety of gene editing is improved.

Abstract: An audio processing method, apparatus and system, capable of realizing the experience of singing Karaoke with other people. The method comprises: acquiring an audio file of a song and a lyric file of the song; playing the audio file at display time corresponding to a first lyric part of the lyric file and recording audio data of a user; playing the audio file at display time corresponding to a second lyric part of the lyric file; and performing audio mixing on the audio data of the user and audio data of the audio file at the display time corresponding to the first lyric part.

Abstract: A karaoke processing method and a karaoke processing system are provided. The method includes: receiving a first antiphonal singing request inputted by a first user; acquiring an accompaniment audio file and a lyrics file of a song from a server based on the first antiphonal singing request, and recording singing performed by the first user based on a part of lyrics by using the accompaniment audio file and the lyrics file, to obtain a first recorded file; determining a first lyrics part based on the first recorded file and generating paragraph information; performing audio mixing processing on the first recorded file and the accompaniment audio file, to obtain a first target file; and sending the first target file and the paragraph information to the server.

Abstract: A karaoke processing method, a karaoke processing apparatus and a karaoke processing system are provided. The method includes: acquiring an accompaniment audio file, an original vocal audio file and a lyrics file of a song, where the lyrics file includes time information for identifying display time of lyrics; dividing the lyrics file to obtain a first and a second lyrics parts and generating lyrics division information; generating a target audio file by outputting the accompaniment audio file in the display time of the first lyrics part and outputting the original vocal audio file in the display time of the second lyrics part; and sending the target audio file and a target lyrics file to a client upon reception of a karaoke request sent by the client, where the target lyrics file is obtained by adding the lyrics division information in the lyrics file.

Abstract: A karaoke processing method and a karaoke processing system are provided. The method includes: receiving a first antiphonal singing request inputted by a first user; acquiring an accompaniment audio file and a lyrics file of a song from a server based on the first antiphonal singing request, and recording singing performed by the first user based on a part of lyrics by using the accompaniment audio file and the lyrics file, to obtain a first recorded file; determining a first lyrics part based on the first recorded file and generating paragraph information; performing audio mixing processing on the first recorded file and the accompaniment audio file, to obtain a first target file; and sending the first target file and the paragraph information to the server.

Abstract: A karaoke processing method, a karaoke processing apparatus and a karaoke processing system are provided. The method includes: acquiring an accompaniment audio file, an original vocal audio file and a lyrics file of a song, where the lyrics file includes time information for identifying display time of lyrics; dividing the lyrics file to obtain a first and a second lyrics parts and generating lyrics division information; generating a target audio file by outputting the accompaniment audio file in the display time of the first lyrics part and outputting the original vocal audio file in the display time of the second lyrics part; and sending the target audio file and a target lyrics file to a client upon reception of a karaoke request sent by the client, where the target lyrics file is obtained by adding the lyrics division information in the lyrics file.

Abstract: An audio processing method, apparatus and system, capable of realizing the experience of singing Karaoke with other people. The method comprises: acquiring an audio file of a song and a lyric file of the song; playing the audio file at display time corresponding to a first lyric part of the lyric file and recording audio data of a user; playing the audio file at display time corresponding to a second lyric part of the lyric file; and performing audio mixing on the audio data of the user and audio data of the audio file at the display time corresponding to the first lyric part.