Patents by Inventor Tian-Xiang Shi

Tian-Xiang Shi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Monoclonal anti-multiple drug resistance antibody, methods of production and uses thereof
    Patent number: 6143873
    Abstract: This invention relates generally to the field of immunology, in particular that of antibodies and antibody productions. More specifically, this invention relates to bispecific antibodies, the hybrid hybridomas which produce them, the parent hybridomas, the production and selection of the hybridomas and hybrid hybridomas, and the purification of the bispecific antibodies. Specific examples relate to bispecific monoclonal antibodies which recognize both the human multi-drug resistance antigen, P-glycoprotein and human Fc.gamma. receptor III (hFc.gamma.RIII. These bispecific antibodies are useful in killing cancer cells.
    Type: Grant
    Filed: June 22, 1999
    Date of Patent: November 7, 2000
    Assignee: Chiron Corporation
    Inventors: David Ring, Tian-Xiang Shi
  • Bispecific antibodies, methods of production and use thereof
    Patent number: 6106833
    Abstract: This invention relates generally to the field of immunology, in particular that of antibodies and antibody productions. More specifically, this invention relates to bispecific antibodies, the hybrid hybridomas which produce them, the parent hybridomas, the production and selection of the hybridomas and hybrid hybridomas, and the purification of the bispecific antibodies. Specific examples relate to bispecific monoclonal antibodies which recognize both the human multi-drug resistance antigen, P-glycoprotein and human Fc.gamma. receptor III (hFc.gamma.RIII). These bispecific antibodies are useful in killing cancer cells.
    Type: Grant
    Filed: November 12, 1997
    Date of Patent: August 22, 2000
    Assignee: Chiron Corporation
    Inventors: David Ring, Tian-Xiang Shi
  • Bispecific antibodies, methods of production and uses thereof
    Patent number: 5959084
    Abstract: This invention relates generally to the field of immunology, in particular that of antibodies and antibody productions. More specifically, this invention relates to bispecific antibodies, the hybrid hybridomas which produce them, the parent hybridomas, the production and selection of the hybridomas and hybrid hybridomas, and the purification of the bispecific antibodies. Specific examples relate to bispecific monoclonal antibodies which recognize both the human multi-drug resistance antigen, P-glycoprotein and human Fc.gamma. receptor III (hFc.gamma.RIII). These bispecific antibodies are useful in killing cancer cells.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: September 28, 1999
    Assignee: Chiron Corporation
    Inventors: David Ring, Tian-Xiang Shi