Patents by Inventor Tianhan HU

Tianhan HU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Alkynyl pyridine prolyl hydroxylase inhibitor, and preparation method and medical use thereof
    Patent number: 10889546
    Abstract: The present invention relates to the field of pharmaceutical chemistry. In particular, the present invention relates to a class of alkynyl pyridine prolyl hydroxylase inhibitors (I). The experiments show that such a compound has good activity of inhibiting prolyl hydroxylase, and can enhance the generation and secretion of erythropoietin in cell or animal models, and thus can promote the generation of red cells, and can be used for the treatment or prevention of anemia, such as chronic kidney disease anemia, and ischemic diseases, including ischemic strokes, myocardial ischemia and other related diseases. The present invention also discloses a method for preparing such a compound.
    Type: Grant
    Filed: November 27, 2015
    Date of Patent: January 12, 2021
    Assignee: Jiangsu Hengrui Medicine Co., Ltd.
    Inventors: Qidong You, Xiaojin Zhang, Yonghua Lei, Tianhan Hu, Xingsen Wu, Haopeng Sun, Xiaoke Guo, Xiaoli Xu
  • ALKYNYL PYRIDINE PROLYL HYDROXYLASE INHIBITOR, AND PREPARATION METHOD AND MEDICAL USE THEREOF
    Publication number: 20200407319
    Abstract: The present invention relates to the field of pharmaceutical chemistry. In particular, the present invention relates to a class of alkynyl pyridine prolyl hydroxylase inhibitors (I). The experiments show that such a compound has good activity of inhibiting prolyl hydroxylase, and can enhance the generation and secretion of erythropoietin in cell or animal models, and thus can promote the generation of red cells, and can be used for the treatment or prevention of anemia, such as chronic kidney disease anemia, and ischemic diseases, including ischemic strokes, myocardial ischemia and other related diseases. The present invention also discloses a method for preparing such a compound.
    Type: Application
    Filed: September 11, 2020
    Publication date: December 31, 2020
    Inventors: Qidong YOU, Xiaojin ZHANG, Yonghua LEI, Tianhan HU, Xingsen WU, Haopeng SUN, Xiaoke GUO, Xiaoli XU
  • ALKYNYL PYRIDINE PROLYL HYDROXYLASE INHIBITOR, AND PREPARATION METHOD AND MEDICAL USE THEREOF
    Publication number: 20180305317
    Abstract: The present invention relates to the field of pharmaceutical chemistry. In particular, the present invention relates to a class of alkynyl pyridine prolyl hydroxylase inhibitors (I). The experiments show that such a compound has good activity of inhibiting prolyl hydroxylase, and can enhance the generation and secretion of erythropoietin in cell or animal models, and thus can promote the generation of red cells, and can be used for the treatment or prevention of anemia, such as chronic kidney disease anemia, and ischemic diseases, including ischemic strokes, myocardial ischemia and other related diseases. The present invention also discloses a method for preparing such a compound.
    Type: Application
    Filed: November 27, 2015
    Publication date: October 25, 2018
    Inventors: Qidong YOU, Xiaojin ZHANG, Yonghua LEI, Tianhan HU, Xingsen WU, Haopeng SUN, Xiaoke GUO, Xiaoli XU