Patents by Inventor Tianjun Liu
Tianjun Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240136784Abstract: A divided-pulse laser regeneration amplification apparatus includes: a signal light coupling component including a first half-wave plate, a first polarization beam splitter, a first Faraday rotator and a second half-wave plate placed in sequence; and a divided-pulse laser regeneration amplification component including a second polarization beam splitter and a third reflector, the second polarization beam splitter is adjacent to the second half-wave plate and is in a same column as the third reflector and the second half-wave plate; a first quarter-wave plate, a Pockels cell and a first reflector are successively arranged on a first side of the second polarization beam splitter, and a third half-wave plate, a first pulse polarization separation component and a first non-linear pulse amplification component are successively arranged on a second side of the second polarization beam splitter.Type: ApplicationFiled: October 17, 2023Publication date: April 25, 2024Inventors: Heping ZENG, Zhengru GUO, Xiaowei QIAN, Tingting LIU, Tianjun YAO
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Patent number: 11944685Abstract: Disclosed in the present disclosure are a novel injection polyaminopolycarboxylic acid-modified abiraterone derivative for treatment of prostate tumor, a pharmaceutical preparation containing the polyaminopolycarboxylic acid-modified abiraterone derivative, a preparation method, and an application. The polyaminopolycarboxylic acid-modified abiraterone derivative has the following structure (I). The polyaminopolycarboxylic acid-modified abiraterone derivative in the present disclosure has good water solubility, can be completely dissolved in an aqueous solution of sodium bicarbonate, is simple and convenient to prepare, high in yield, and suitable for large-scale production, has a remarkable effect in resisting tumors, can be used for treating prostate cancer tumor, and has the characteristics of high efficiency and low toxicity.Type: GrantFiled: March 14, 2022Date of Patent: April 2, 2024Assignee: TIANJIN HAIRUNJAHE INNOVATIVE PHARMACEUTICAL RESEARCH LIMITED LIABILITY COMPANYInventors: Tianjun Liu, Na Zhu, Yumei Rong, Ge Hong
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Publication number: 20240042041Abstract: Disclosed in the present disclosure are a novel injection polyaminopolycarboxylic acid-modified abiraterone derivative for treatment of prostate tumor, a pharmaceutical preparation containing the polyaminopolycarboxylic acid-modified abiraterone derivative, a preparation method, and an application. The polyaminopolycarboxylic acid-modified abiraterone derivative has the following structure (I). The polyaminopolycarboxylic acid-modified abiraterone derivative in the present disclosure has good water solubility, can be completely dissolved in an aqueous solution of sodium bicarbonate, is simple and convenient to prepare, high in yield, and suitable for large-scale production, has a remarkable effect in resisting tumors, can be used for treating prostate cancer tumor, and has the characteristics of high efficiency and low toxicity.Type: ApplicationFiled: March 14, 2022Publication date: February 8, 2024Inventors: Tianjun LIU, Na ZHU, Yumei RONG, Ge HONG
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Publication number: 20220195550Abstract: An example track shoe, cutting edge, or other component of a machine is formed in a heated process, such as hot-rolling followed by air-hardening. The air-hardening process involves cooling the component by flowing air over the component (e.g., air cooling), such that the component is cooled at a controlled rate. During the air-cooling process, such as in the range of about 250° C. to about 1100° C., the component may be machined, such as by shearing, punching, drilling, etc. The machining may form the final shape of the component. As the air-hardening process is completed, and the component approaches room temperature, the component may have at least 5% bainitic crystal composition, and as high as greater than 80% bainitic crystal composition, resulting in relatively high hardness and fracture toughness. The final track shoe may have a hardness between about 40 HRC and 55 HRC.Type: ApplicationFiled: December 23, 2020Publication date: June 23, 2022Applicant: Caterpillar Inc.Inventors: Matthew Thomas Kiser, Lindsey S. Cavanaugh, Thomas Marshall Congdon, Susan Marie Graham, Tianjun Liu, Mark David Veliz, Thomas John Yaniak
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Patent number: 11346218Abstract: Provided is a guiding type miniature pipe-jacking construction method, comprising the following steps: in an originating well, perforating an operation hole in an inner wall of the originating well with a trepanning apparatus; mounting a laser orientation instrument and a laser guided drill bit, driving a guide bar connected with the laser guided drill bit into the opened operation hole with a thrusting apparatus, and driving the guide bar into a soil mass with the thrusting apparatus; jacking a plurality of mud discharging pipes following the guide bar successively into the soil mass with the thrusting apparatus; jacking a plurality of mud discharging screw rods into the mud discharging pipes with the thrusting apparatus; jacking a pipe-jacking machine head following the mud discharging pipes into the soil mass with the thrusting apparatus, a cutter head on the pipe-jacking machine head rotating to drive the mud discharging screw rods to rotate.Type: GrantFiled: October 29, 2021Date of Patent: May 31, 2022Assignee: GUANGZHOU MUNICIPAL ENGINEERING GROUP LTD.Inventors: Guanfeng An, Jingda Ouyang, Haibin Yu, Rong Zhang, Tianjun Liu, Tan Wang, Yuanwen Li, Zhaobao Hou, Deyi Xu
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Patent number: 11028457Abstract: A method of heat treating a fastening member having a head portion, a shank portion, and a thread portion includes hardening the fastening member to a first hardness value. Hardening of the fastening member includes heating the fastening member at a first pre-set temperature value. The method also includes tempering the fastening member at a second pre-set temperature value to a second hardness value. The method further includes induction tempering the thread portion of the fastening member. Induction tempering of the thread portion includes heating the thread portion at a third pre-set temperature value to a third hardness value. The third hardness value of the thread portion is less than the second hardness value of the head portion and the shank portion.Type: GrantFiled: July 17, 2017Date of Patent: June 8, 2021Assignee: Caterpillar Inc.Inventor: Tianjun Liu
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Publication number: 20190017141Abstract: A method of heat treating a fastening member having a head portion, a shank portion, and a thread portion includes hardening the fastening member to a first hardness value. Hardening of the fastening member includes heating the fastening member at a first pre-set temperature value. The method also includes tempering the fastening member at a second pre-set temperature value to a second hardness value. The method further includes induction tempering the thread portion of the fastening member. Induction tempering of the thread portion includes heating the thread portion at a third pre-set temperature value to a third hardness value. The third hardness value of the thread portion is less than the second hardness value of the head portion and the shank portion.Type: ApplicationFiled: July 17, 2017Publication date: January 17, 2019Applicant: Caterpillar Inc.Inventor: Tianjun Liu
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Patent number: 10045954Abstract: The invention discloses a use of paracetamol and a pharmaceutical preparation containing the same in preparation of anti-HPV drugs. The novel anti-HPV pharmaceutical preparation of the invention has a significant anti-HPV effect and low toxicity, and can be used for preventing and treating clinical symptoms caused by HPV infection, especially common warts, plane warts, plantar wart, vulvar cancer, penile neoplasms, anal carcinoma, prostate cancer, bladder cancer, cervical cancer, rectal cancer, oral cancer, tonsil cancer and the like.Type: GrantFiled: July 14, 2014Date of Patent: August 14, 2018Assignee: INSTITUTE OF BIOMEDICAL ENGINEERING, CHINESE ACADEMY OF MEDICAL SCIENCEInventors: Tianjun Liu, Shuai Meng, Lihui Zhao, Ge Hong
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Publication number: 20160279081Abstract: The invention discloses a use of paracetamol and a pharmaceutical preparation containing the same in preparation of anti-HPV drugs. The novel anti-HPV pharmaceutical preparation of the invention has a significant anti-HPV effect and low toxicity, and can be used for preventing and treating clinical symptoms caused by HPV infection, especially common warts, plane warts, plantar wart, vulvar cancer, penile neoplasms, anal carcinoma, prostate cancer, bladder cancer, cervical cancer, rectal cancer, oral cancer, tonsil cancer and the like.Type: ApplicationFiled: July 14, 2014Publication date: September 29, 2016Applicant: INSTITUTE OF BIOMEDICAL ENGINEERING CHINESEInventors: Tianjun LIU, Shuai MENG, Lihui ZHAO, Ge HONG
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Patent number: 9440693Abstract: A method of producing a forged steel part is disclosed. The method includes providing a steel billet that can be selectively hardened to different hardness levels by varying the air cooling rate. The method also includes heating the steel billet to an austenization temperature of the steel billet. The method further includes hot forging the steel billet to form the steel part including a first region and a second region. The method yet further includes selectively cooling the hot forged steel part by air cooling the first region at a first cooling rate and air cooling the second region at a second cooling rate that is less than the first cooling rate.Type: GrantFiled: March 20, 2014Date of Patent: September 13, 2016Assignee: Caterpillar Inc.Inventors: Tianjun Liu, Matthew Thomas Kiser
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Publication number: 20160168708Abstract: A method of manufacturing a component includes providing a component machined or forged from an air-hardenable steel, and placing the component in a chemical vapor deposition (CVD) processing chamber. The method may include controlling the pressure within the processing chamber to a pressure that is below atmospheric pressure, inducting feedstock gases into the processing chamber, and increasing the temperature inside the processing chamber to a coating temperature at which one or more volatile precursors from the feedstock gases react on the surface of the component to produce a thin film coating. The temperature in the processing chamber may be maintained at the coating temperature for a period of time that includes at least one of a period of time before, during, and after the thin film coating is produced in order to austenitize the material of the component.Type: ApplicationFiled: December 10, 2014Publication date: June 16, 2016Applicant: CATERPILLAR INC.Inventors: Steven TAYLOR, Tianjun LIU, Scott JOHNSTON
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Publication number: 20150376750Abstract: A method of producing a forged steel part is disclosed to include providing a steel billet having a composition including 0.25-0.40 wt. % C, 1.50-3.00 wt. % Mn, 0.30-2.00 wt. % Si, 0.00-0.150 wt. % V, 0.02-0.06 wt. % Ti, 0.010-0.04 wt. % S, 0.0050-0.0150 wt. % N, 0.00-1.00 wt. % Cr, 0.00-0.30 wt. % Mo, 0.00-0.003 wt. % B, and a balance of Fe and incidental impurities. The method may further include heating the steel billet to an austenization temperature of approximately 1150 degrees C. to 1350 degrees C., hot forging the steel billet to form the steel part, and controlled air cooling the forged steel part after the hot forging. The method may still further include induction heating select portions of the forged steel part after the controlled air cooling to increase the hardness of the select portions of the forged steel part, followed by quenching and tempering before the final machining.Type: ApplicationFiled: September 4, 2015Publication date: December 31, 2015Inventors: Tianjun LIU, Matthew Thomas KISER
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Publication number: 20150266526Abstract: A method of producing a forged steel part is disclosed. The method includes providing a steel billet that can be selectively hardened to different hardness levels by varying the air cooling rate. The method also includes heating the steel billet to an austenization temperature of the steel billet. The method further includes hot forging the steel billet to form the steel part including a first region and a second region. The method yet further includes selectively cooling the hot forged steel part by air cooling the first region at a first cooling rate and air cooling the second region at a second cooling rate that is less than the first cooling rate.Type: ApplicationFiled: March 20, 2014Publication date: September 24, 2015Applicant: CATERPILLAR INC.Inventors: Tianjun Liu, Matthew Thomas Kiser
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Publication number: 20150132495Abstract: A machine component may include a body made of an iron alloy. The body may include a surface, and a coating fused to the surface. The coating may be an alloy including phosphorous, carbon, and iron. The coating may have solidus temperature of less than or equal to about 1000° C., and a hardness greater than or equal to about 50 HRC.Type: ApplicationFiled: January 16, 2015Publication date: May 14, 2015Applicant: CATERPILLAR INC.Inventors: Tianjun Liu, Marvin Grendel McKimpson
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Patent number: 9017823Abstract: A machine component may include a body made of an iron alloy. The body may include a surface, and a coating fused to the surface. The coating may be an alloy including phosphorous, carbon, and iron. The coating may have solidus temperature of less than or equal to about 1000° C., and a hardness greater than or equal to about 50 HRC.Type: GrantFiled: December 19, 2011Date of Patent: April 28, 2015Assignee: Caterpillar Inc.Inventors: Tianjun Liu, Marvin Grendel McKimpson
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Publication number: 20150037198Abstract: A steel article is provided for improved wear resistance due to optimized hardness, toughness and temper resistance. In one exemplary embodiment, the steel article may have a composition including about 0,2 to 0.43 percent by weight of carbon, about 0.5 to about 3.0 percent by weight of silicon, about 0.01 to about 3.0 percent by weight of chromium, and 0.43 to about 2.5 percent by weight of vanadium.Type: ApplicationFiled: July 30, 2013Publication date: February 5, 2015Applicant: Caterpillar Inc.Inventors: Tianjun Liu, Mohammed Maniruzzaman, Matthew Thomas Kiser, Thomas John Yaniak
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Patent number: 8905493Abstract: A composite track link is provided that has a body and a replaceable rail brazed or soldered together to provide a metallurgical bond between the track link body and the rail such that the rail may be removed and replaced by heating the track link or the brazing or soldering filler metal when the rail becomes worn. This process enables the rail to be separated from the body of the track link so a new rail can be brazed or soldered to the body of the track link. As a result, track links or bodies of track links may outlast the rails by multiple use cycles. Further, the body and rail may be formed of different materials.Type: GrantFiled: May 11, 2011Date of Patent: December 9, 2014Assignee: Caterpillar Inc.Inventor: Tianjun Liu
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Publication number: 20140283960Abstract: A method of producing a forged steel part is disclosed to include providing a steel billet having a composition including 0.25-0.40 wt. % C, 1.50-3.00 wt. % Mn, 0.30-2.00 wt. % Si, 0.00-0.150 wt. % V, 0.02-0.06 wt. % Ti, 0.010-0.04 wt. % S, 0.0050-0.0150 wt. % N, 0.00-1.00 wt. % Cr, 0.00-0.30 wt. % Mo, 0.00-0.003 wt. % B, and a balance of Fe and incidental impurities. The method may further include heating the steel billet to an austenization temperature of approximately 1150 degrees C. to 1350 degrees C., hot forging the steel billet to form the steel part, and controlled air cooling the forged steel part after the hot forging. The method may still further include induction heating select portions of the forged steel part after the controlled air cooling to increase the hardness of the select portions of the forged steel part, followed by quenching and tempering before the final machining.Type: ApplicationFiled: March 22, 2013Publication date: September 25, 2014Applicant: Caterpillar Inc.Inventors: Tianjun LIU, Matthew Thomas KISER
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Publication number: 20130157081Abstract: A machine component may include a body made of an iron alloy. The body may include a surface, and a coating fused to the surface. The coating may be an alloy including phosphorous, carbon, and iron. The coating may have solidus temperature of less than or equal to about 1000° C., and a hardness greater than or equal to about 50 HRC.Type: ApplicationFiled: December 19, 2011Publication date: June 20, 2013Inventors: Tianjun Liu, Marvin Grendel McKimpson
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Publication number: 20120312159Abstract: A machine component includes a body made of cast iron. The body may include a surface configured to be subject to cavitation-induced erosion. The component may also include a hardened covering on the surface of the body. The covering may have a crystal structure including martensite and between about 5% to about 40% austenite.Type: ApplicationFiled: June 10, 2011Publication date: December 13, 2012Inventors: Tianjun Liu, Marvin Grendel McKimpson