Abstract: Provided herein are compounds of Formula (I): and forms thereof, including compositions thereof and uses therewith for treating spinal muscular atrophy.

Abstract: Disclosed in the present invention are an energy-saving dishwasher and a control method therefor. The inner container is arranged inside the housing, the inner container is internally provided with a manifold type dish rack for placing dishes and spraying steam to perform steam cleaning on the dishes, and the manifold type dish rack is placed on a supporting frame fixed to the inner container. A water storage tank, a steam/hot water integrated generating device and a water pump are arranged below the inner container, and the steam/hot water integrated generating device includes a generating assembly and a control assembly. The manifold type dish rack is configured to place the dishes and simultaneously sprays steam to clean the dishes. The steam/hot water integrated generating device is configured to generate steam and hot water, heating is performed to generate the steam, and then relative cooling is performed to generate the hot water.

Abstract: Disclosed is a targeted delivery system for a hydrophobic antitumor drug, referring to conjugates of E-selectin polypeptide ligand-polyethylene glycol-antitumor drug connected by different link bridges containing disulfide bonds. The synthesis of the conjugates, antitumor activity evaluation, the particle size and morphology characteristics of nanoparticles self-assembled by the conjugates in an aqueous solution, and the release of the antitumor drug in different conditions are comprised. The conjugates can actively target at vessels of a tumor site by the E-selectin peptide ligand, and can also self-assemble into nanoparticles in an aqueous solution, so as to be passively targeted at the tumor site by EPR effect.

Abstract: A method to create and run a program in a computer including includes: connecting a preset USB-HID device to a computer, wherein the USB-HID device is provided with a first storage area, stores working codes in the first storage area in binary form; the USB-HID device injects a control instruction to the computer, such that the computer creates a text document or opens a command line program according to the control instruction; if the computer creates a text document, the USB-HID device inputs the working codes in the form of keyboard sequence to generate an application corresponding to the working codes, and controls the computer to run the application; and if the computer opens a command line program, the USB-HID device inputs the working codes in the form of keyboard sequence, such that the computer directly runs the working codes through the command line program.

Abstract: Disclosed is a targeted delivery system for a hydrophobic antitumor drug, referring to conjugates of E-selectin polypeptide ligand-polyethylene glycol-antitumor drug connected by different link bridges containing disulfide bonds. The synthesis of the conjugates, antitumor activity evaluation, the particle size and morphology characteristics of nanoparticles self-assembled by the conjugates in an aqueous solution, and the release of the antitumor drug in different conditions are comprised. The conjugates can actively target at vessels of a tumor site by the E-selectin peptide ligand, and can also self-assemble into nanoparticles in an aqueous solution, so as to be passively targeted at the tumor site by EPR effect.

Abstract: A movable medical case includes a medical case housing, a medicine box and drawers. The drawers are installed inside the medicine box. The medicine box is installed inside the medical case housing. Drawer driving devices are installed in the medical case housing. The drawer driving devices pass through the medicine box and are detachably connected with the drawers, and the drawers are driven to get out of or enter the medical case housing.

Abstract: A movable medical case is disclosed. The movable medical case comprises a medical case housing (1), a medicine box (2) and drawers (3). The drawers (3) are installed inside the medicine box (2). The medicine box (2) is installed inside the medical case housing (1). Drawer driving devices are installed in the medical case housing (1). The drawer driving devices pass through the medicine box (2) and are detachably connected with the drawers (3), and the drawers (3) are driven to get out of or enter the medical case housing. The medicine box of the movable medical case is simple in structure, and reasonable in arrangement. There is no any electric connection between the medicine box and the medical case housing, the universality of the medical case housing is improved, and the automation control demands are met.