Abstract: A display substrate and a display device are provided. In the display substrate, the display sub-pixel is located in a display region, the display sub-pixel and includes a first display sub-pixel, a second display sub-pixel, a third display sub-pixel, and a fourth display sub-pixel that emit light of colors different from each other; the dummy sub-pixel is located in a periphery region, the periphery region includes a dummy region and an edge region, the dummy sub-pixel is located in the dummy region of the periphery region, the dummy sub-pixel includes a first dummy sub-pixel, a second dummy sub-pixel, a third dummy sub-pixel, and a fourth dummy sub-pixel; and the display substrate further includes a spacer including a plurality of first spacers and a plurality of second spacers, the plurality of first spacers are located in the periphery region, the plurality of second spacers are located in the display region.

Abstract: An implantable prosthetic valve assembly, according to one embodiment, comprises a frame assembly including a plurality of struts and a prosthetic valve secured inside the frame assembly by one or more sutures. At least one of the plurality of spaced struts contains a recess that accepts a portion of the one or more sutures.

Abstract: The present disclosure relates to the technical field of filters, in particular to a foldable filter element, including a foldable filter assembly, a bottom setting end cover that is covered at a bottom end of the foldable filter assembly, a top setting end cover that is covered at an upper end of the foldable filter assembly, first sealing cotton arranged between the bottom setting end cover and the foldable filter assembly, and second sealing cotton arranged between the top setting end cover and the foldable filter assembly. The present disclosure has the characteristics of rational structure setting and effectively reducing the structure complexity and reducing the production cost. In addition, the present disclosure further provides a filter with the foldable filter element.

Abstract: The present invention provides a method of site-directed insertion to H11 locus in pigs by using site-directed cutting system, includes the following steps: 1) identify the targeted sequence targeted by the targeted cutting system in the targeted genome sequence of pigs; 2) design and construct the targeting sequence of the corresponding cutting system according to the targeted site; 3) construction of targeting vector; 4) transfect cells, identify the efficiency of fixed-point insertion by PCR amplification. The invention is dependent on the site-directed cutting system of H11 locus in pigs, to insert the target gene into the target site, in order to solve the problems such as low efficiency of traditional shooting technique, inconvenience design of PCR detection primer, harder to detect. The invention provides a method of site-directed insertion which can stably express the foreign gene at the H11 locus, to build an efficient platform for the production of transgenic pigs.