Patents by Inventor Tianyi Ke

Tianyi Ke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ferritin Heavy Chain Subunit-Based Conjugates and Application Thereof
    Publication number: 20230203111
    Abstract: The present invention relates to the field of biological medicines. Specifically, the present invention relates to a conjugate based on a ferritin heavy chain subunit and use thereof.
    Type: Application
    Filed: May 17, 2021
    Publication date: June 29, 2023
    Inventors: Tianyi Ke, Hui Ding, Dehui Yao, Fang Lao, Haiyong Yu, Jianwei Cheng, Fangxing Ouyang
  • POLYMERIC DRUG CONJUGATES WITH TETHER GROUPS FOR CONTROLLED DRUG DELIVERY
    Publication number: 20210154308
    Abstract: Described herein is a cyclodextrin containing polymer conjugate.
    Type: Application
    Filed: June 25, 2020
    Publication date: May 27, 2021
    Inventors: Mark E. Davis, Jungyeon Hwang, Tianyi Ke, Ching-jou Lim, Thomas Schluep
  • POLYMERIC DRUG CONJUGATES WITH TETHER GROUPS FOR CONTROLLED DRUG DELIVERY
    Publication number: 20180008719
    Abstract: Described herein is a cyclodextrin containing polymer conjugate.
    Type: Application
    Filed: February 16, 2017
    Publication date: January 11, 2018
    Inventors: Mark E. Davis, Jungyeon Hwang, Tianyi Ke, Ching-jou Lim, Thomas Schluep
  • Polymer drug conjugates with tether groups for controlled drug delivery
    Patent number: 9610360
    Abstract: Described herein is a cyclodextrin containing polymer conjugate.
    Type: Grant
    Filed: June 20, 2013
    Date of Patent: April 4, 2017
    Assignee: CERULIEAN PHARMA INC.
    Inventors: Mark E. Davis, Jungyeon Hwang, Tianyi Ke, Ching-jou Lim, Thomas Schluep
  • POLYMER DRUG CONJUGATES WITH TETHER GROUPS FOR CONTROLLED DRUG DELIVERY
    Publication number: 20130288986
    Abstract: Described herein is a cyclodextrin containing polymer conjugate.
    Type: Application
    Filed: June 20, 2013
    Publication date: October 31, 2013
    Inventors: Mark E. Davis, Jungyeon Hwang, Tianyi Ke, Ching-jou Lim, Thomas Schluep
  • Cyclodextrin-based polymers for therapeutics delivery
    Patent number: 8497365
    Abstract: The present invention relates to novel compositions comprising polymeric moieties covalently attached to therapeutic agents, wherein the therapeutic agent is attached to the polymeric moiety through a tether. By selecting from a variety of tether groups and targeting ligands the polymers present methods for controlled delivery of the therapeutic agents. The invention also relates to methods of treating subjects with the therapeutic compositions described herein.
    Type: Grant
    Filed: August 4, 2011
    Date of Patent: July 30, 2013
    Inventors: Mark E. Davis, Jungyeon Hwang, Tianyi Ke, Ching-Jou Lim, Thomas Schluep
  • CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTICS DELIVERY
    Publication number: 20110294998
    Abstract: The present invention relates to novel compositions comprising polymeric moieties covalently attached to therapeutic agents, wherein the therapeutic agent is attached to the polymeric moiety through a tether. By selecting from a variety of tether groups and targeting ligands the polymers present methods for controlled delivery of the therapeutic agents. The invention also relates to methods of treating subjects with the therapeutic compositions described herein.
    Type: Application
    Filed: August 4, 2011
    Publication date: December 1, 2011
    Applicant: CERULEAN PHARMA INC.
    Inventors: Mark E. Davis, Jungyeon Hwang, Tianyi Ke, Ching-Jou Lim, Thomas Schluep
  • CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTICS DELIVERY
    Publication number: 20110282047
    Abstract: Described herein is a cyclodextrin containing polymer conjugate.
    Type: Application
    Filed: July 25, 2011
    Publication date: November 17, 2011
    Applicant: CERULEAN PHARMA INC.
    Inventors: Mark E. Davis, Jungyeon Hwang, Tianyi Ke, Ching-Jou Lim, Thomas Schluep
  • MRI-Guided Photodynamic Therapy For Cancer
    Publication number: 20090076571
    Abstract: Disclosed is a method of therapy used in combination with a diagnostic tool for enhanced photodynamic therapy using MRI, called (magnetic resonance imaging)-guided photodynamic therapy. The methods of the present invention includes administration of MRI contrast agent labeled polymer photosensitizer conjugates, detection and localization of tumor or cancer tissues with contrast-enhanced MRI and specific illumination and treatment of localized target tissues, such as tumors or cancer cells, using laser energy. The delivered laser energy activates the photosensitizer accumulated in the target tissue, resulting in treatment. Also disclosed are novel conjugate compounds, such as PLGA-Mce6-DOTA-Gd complexes, having multi-functionality in that the complex may include an MRI contrasting agent linked to a photosensitizing agent.
    Type: Application
    Filed: December 2, 2005
    Publication date: March 19, 2009
    Inventors: Zheng-Rong Lu, Anagha Vaidya, Tianyi Ke
  • Cyclodextrin-based polymers for therapeutics delivery
    Publication number: 20080176958
    Abstract: The present invention relates to novel compositions comprising polymeric moieties covalently attached to therapeutic agents, wherein the therapeutic agent is attached to the polymeric moiety through a tether. By selecting from a variety of tether groups and targeting ligands the polymers present methods for controlled delivery of the therapeutic agents. The invention also relates to methods of treating subjects with the therapeutic compositions described herein.
    Type: Application
    Filed: December 14, 2007
    Publication date: July 24, 2008
    Applicant: Insert Therapeutics, Inc.
    Inventors: Mark E. Davis, Jungyeon Hwang, Tianyi Ke, Ching-Jou Lim, Thomas Schluep