Abstract: Provided are a pixel circuit, display apparatus and driving method. The pixel circuit includes: a light-emitting device, a driving transistor configured to generate a driving current that drives the light-emitting device to emit light according to a data voltage, a light-emitting control circuit coupled with the driving transistor and configured to, in response to an effective level of a light-emitting control signal terminal, provide a driving current generated by the driving transistor to the light-emitting device, and drive the light-emitting device to emit light; a data-writing circuit coupled with a first electrode of the driving transistor and configured to operate in response to a plurality of effective levels that occur at intervals between first scanning signal terminals; and a threshold compensation circuit coupled with the driving transistor.

Abstract: A display device includes a blocking dam. The blocking dam includes an insulation layer group. A groove is provided at one side of the insulation layer group away from the substrate. After the liquid organic encapsulation material flows from the display area to the highest point of the blocking dam, the excess liquid organic encapsulation material may directly fall into the groove, avoiding the excess liquid organic encapsulation material from flowing across the blocking dam to the outside of the encapsulation area, causing that the orthographic projection of the edge of the organic encapsulation layer, away from the display area, on the substrate is located within the orthographic projection of the blocking dam on the substrate. The display panel includes only one blocking dam, and the width of the area, where the blocking dam is provided, of the non-display area decreases, thereby reducing the width of the entire non-display area.

Abstract: The present invention relates to novel compounds of Formulae I-XI: wherein each A, A?, Q, Q?, W, Rw, Y, and Z, and -- are as defined herein, which inhibit NOD-like receptor protein 3 (NLRP3) inflammasome activity. The invention further relates to the processes for their preparation, pharmaceutical compositions and medicaments containing them, and their use in the treatment of diseases and disorders mediated by NLRP3.

Abstract: A collision avoidance device, includes a license plate frame, a first sensor mounted to the license plate frame to determine a distance of a following vehicle to the license plate frame and a second sensor mounted to the license plate frame to determine a velocity of the license plate frame, a logic circuit electrically coupled to the first sensor and the second sensor, wherein the logic circuit, determines a safe trailing distance between the license plate frame and the following vehicle based upon the velocity of the license plate frame and determines whether the following vehicle is closer than the safe trailing distance to the license plate frame and a warning light is coupled to the license plate frame to illuminate the license plate frame if the following vehicle is closer than the safe trailing distance.

Abstract: The embodiments of the present disclosure relate to antigens of ?-coronaviruses, preparation methods and uses thereof. The amino acid sequence of the antigen of the ?-coronavirus includes an amino acid sequence arranged in a (A-B)-(A-B) pattern or an amino acid sequence arranged in a (A-B)-C-(A-B) pattern or an amino acid sequence arranged in a (A-B)-(A-B?) pattern or an amino acid sequence arranged in a (A-B)-C-(A-B?) pattern. The antigen of the ?-coronavirus has a single-chain dimer structure. A single-chain dirtier expressed according to examples of the present disclosure is stable in content and has excellent immunogenicity as an antigen of a ?-coronavirus, and a vaccine prepared by using the single-chain dimer as an antigen of a ?-coronavirus can elicit high-titer neutralizing antibodies in mice.

Abstract: A collision avoidance device, includes a license plate frame, a first sensor mounted to the license plate frame to determine a distance of a following vehicle to the license plate frame and a second sensor mounted to the license plate frame to determine a velocity of the license plate frame, a logic circuit electrically coupled to the first sensor and the second sensor, wherein the logic circuit, determines a safe trailing distance between the license plate frame and the following vehicle based upon the velocity of the license plate frame and determines whether the following vehicle is closer than the safe trailing distance to the license plate frame and a warning light is coupled to the license plate frame to illuminate the license plate frame if the following vehicle is closer than the safe trailing distance.

Abstract: The embodiments of the present disclosure relate to antigens of ?-coronaviruses, preparation methods and uses thereof. The amino acid sequence of the antigen of the ?-coronavirus includes an amino acid sequence arranged in a (A-B)-(A-B) pattern or an amino acid sequence arranged in a (A-B)-C-(A-B) pattern or an amino acid sequence arranged in a (A-B)-(A-B?) pattern or an amino acid sequence arranged in a (A-B)-C-(A-B?) pattern. The antigen of the ?-coronavirus has a single-chain dimer structure. A single-chain dirtier expressed according to examples of the present disclosure is stable in content and has excellent immunogenicity as an antigen of a ?-coronavirus, and a vaccine prepared by using the single-chain dimer as an antigen of a ?-coronavirus can elicit high-titer neutralizing antibodies in mice.