Patents by Inventor Tianyuan Zhou

Tianyuan Zhou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220241320
    Abstract: The present embodiments provide methods, compounds, and compositions useful for inhibiting IRF4 expression, which may be useful for treating, preventing, or ameliorating a cancer associated with IRF4.
    Type: Application
    Filed: December 17, 2021
    Publication date: August 4, 2022
    Inventors: Tianyuan ZHOU, Youngsoo KIM, Robert MACLEOD, Huynh-Hoa BUI, Susan M. FREIER
  • Publication number: 20220089498
    Abstract: A multicolor light-storing ceramic for fire-protection indication and a preparation method thereof are provided. The preparation method includes: adding a glass based raw material, a light-storing powder, a dispersant and an alumina powder into a granulator, adding water mixed with a pore-forming agent and then mechanically stirring for granulation; adding a plasticizer after the stirring of 4˜8 h, and continuing the stirring for 1˜3 h to thereby obtain a mixture; packing the mixture into a mold and performing tableting; demolding and obtaining a light-storing self-luminous quartz ceramic by drying and firing using a kiln; printing a pattern onto a surface of the ceramic and then curing to obtain a light-storing ceramic for indication sign.
    Type: Application
    Filed: December 1, 2021
    Publication date: March 24, 2022
    Inventors: Le Zhang, Shunshun Yang, Rui Wang, Jin Huang, Zhanran Wang, Xiaoyu Zhu, Jian Kang, Can Huang, Bingheng Sun, Tianyuan Zhou, Hao Chen
  • Publication number: 20220089499
    Abstract: A preparation method for improving light efficiency and stability of light storing ceramics is provided. Calcium ethanol solution is added into titanium precursor solution firstly and oleic acid dispersant is added, pure water and the light storing powder are subsequently added to obtain a light-storing powder-calcium titanate gel, and dried, crushed and sieved to obtain xerogel powder. Glass matrix material, sieved xerogel powder and another dispersant are placed into a granulator, and directly mechanically stirred and granulated after adding pure water. A plasticizer is added after stirring 4˜8 h, and continuously stirred for 1˜3 h to obtain a mixture, pressing, drying and firing. Calcium titanate is manually introduced to protect the light-storing powder from hydrolysis or high-temperature oxidation. It can also change the propagation path of fluorescence inside ceramics, improve light absorption and fluorescence output efficiency and is conducive to ceramic molding.
    Type: Application
    Filed: December 1, 2021
    Publication date: March 24, 2022
    Inventors: Le Zhang, Shunshun Yang, Rui Wang, Tao Li, Xiaowen Zhu, Xinyu Jiang, Guocan Huang, Jian Kang, Bingheng Sun, Cen Shao, Tianyuan Zhou, Hao Chen
  • Patent number: 11241451
    Abstract: The present embodiments provide methods, compounds, and compositions useful for inhibiting IRF4 expression, which may be useful for treating, preventing, or ameliorating a cancer associated with IRF4.
    Type: Grant
    Filed: March 1, 2019
    Date of Patent: February 8, 2022
    Assignee: Ionis Pharmaceuticals, Inc.
    Inventors: Tianyuan Zhou, Youngsoo Kim, Robert MacLeod, Huynh-Hoa Bui, Susan M. Freier
  • Publication number: 20210038631
    Abstract: The present embodiments provide methods, compounds, and compositions useful for inhibiting IRF4 expression, which may be useful for treating, preventing, or ameliorating a cancer associated with IRF4.
    Type: Application
    Filed: March 1, 2019
    Publication date: February 11, 2021
    Applicant: Ionis Pharmaceuticals, Inc.
    Inventors: Tianyuan Zhou, Youngsoo Kim, Robert MacLeod, Huynh-Hoa Bui, Susan M. Freier
  • Patent number: 9567588
    Abstract: Certain embodiments are directed to compounds and compositions targeted to human androgen receptor (AR) for inhibiting androgen receptor levels in a cell, which can be useful for methods of treating cancer and inhibiting cancer cell growth or proliferation.
    Type: Grant
    Filed: September 15, 2015
    Date of Patent: February 14, 2017
    Assignee: Ionis Pharmaceuticals, Inc.
    Inventors: Robert A. Macleod, Youngsoo Kim, Tianyuan Zhou, Susan M. Freier, Punit Seth, Eric Swayze, Brett Monia
  • Publication number: 20160068846
    Abstract: Certain embodiments are directed to compounds and compositions targeted to human androgen receptor (AR) for inhibiting androgen receptor levels in a cell, which can be useful for methods of treating cancer and inhibiting cancer cell growth or proliferation.
    Type: Application
    Filed: September 15, 2015
    Publication date: March 10, 2016
    Applicant: ISIS PHARMACEUTICALS INC.
    Inventors: Robert A. Macleod, Youngsoo Kim, Tianyuan Zhou, Susan M. Freier, Punit Seth, Eric Swayze, Brett Monia
  • Patent number: 9175291
    Abstract: Certain embodiments are directed to compounds and compositions targeted to human androgen receptor (AR) for inhibiting androgen receptor levels in a cell, which can be useful for methods of treating cancer and inhibiting cancer cell growth or proliferation.
    Type: Grant
    Filed: October 10, 2013
    Date of Patent: November 3, 2015
    Assignee: ISIS Pharmaceuticals Inc.
    Inventors: Robert A. Macleod, Youngsoo Kim, Tianyuan Zhou, Susan M. Freier, Brett Monia
  • Publication number: 20140107180
    Abstract: Certain embodiments are directed to compounds and compositions targeted to human androgen receptor (AR) for inhibiting androgen receptor levels in a cell, which can be useful for methods of treating cancer and inhibiting cancer cell growth or proliferation.
    Type: Application
    Filed: October 10, 2013
    Publication date: April 17, 2014
    Applicant: ISIS PHARMACEUTICALS INC.
    Inventors: Robert A. Macleod, Youngsoo Kim, Tianyuan Zhou, Susan M. Freier, Punit Seth, Eric Swayze, Brett Monia
  • Patent number: RE48461
    Abstract: Certain embodiments are directed to compounds and compositions targeted to human androgen receptor (AR) for inhibiting androgen receptor levels in a cell, which can be useful for methods of treating cancer and inhibiting cancer cell growth or proliferation.
    Type: Grant
    Filed: February 13, 2019
    Date of Patent: March 9, 2021
    Assignee: lonis Pharmaceuticals, Inc.
    Inventors: Robert A. Macleod, Youngsoo Kim, Tianyuan Zhou, Susan M. Freier, Punit Seth, Eric Swayze, Brett Monia