Abstract: A method for preparing glucopyranosyl derivatives as sodium dependent glucose cotransporter (SGLT) inhibitors, an intermediate thereof, and a method for preparing the intermediate.

Abstract: A glucopyranosyl derivative is used as an inhibitor of sodium-dependent glucose transporters (SGLTs), particularly being used as an inhibitor of sodium-dependent glucose transporter-1 (SGLT1), and a pharmaceutically acceptable salt or stereoisomer thereof, further relating to a pharmaceutical composition containing the derivative. The compound and a pharmaceutical composition is used thereof in the preparation of a drug for treating diabetes and diabetes-related diseases.

Abstract: A glucopyranosyl derivative is used as an inhibitor of sodium-dependent glucose transporters (SGLTs), particularly being used as an inhibitor of sodium-dependent glucose transporter-1 (SGLT1), and a pharmaceutically acceptable salt or stereoisomer thereof, further relating to a pharmaceutical composition containing the derivative. The compound and a pharmaceutical composition is used thereof in the preparation of a drug for treating diabetes and diabetes-related diseases.

Abstract: The invention discloses a rapidly mountable ceiling loudspeaker device comprising a loudspeaker housing, a ceiling locking assembly, a woofer module and a dustproof assembly. The loudspeaker housing comprises a basket, a speaker inner frame and a surface frame ring body; the ceiling locking assembly comprises a locking sleeve body, a ceiling locking piece and a locking member; the woofer module is arranged in the basket; and the dustproof assembly is arranged on the speaker inner frame. After the scheme is employed, the ceiling loudspeaker device can be efficiently assembled and disassembled without the aid of a mounting tool.

Abstract: The invention discloses a rapidly mountable ceiling loudspeaker device comprising a loudspeaker housing, a ceiling locking assembly, a woofer module and a dustproof assembly. The loudspeaker housing comprises a basket, a speaker inner frame and a surface frame ring body; the ceiling locking assembly comprises a locking sleeve body, a ceiling locking piece and a locking member; the woofer module is arranged in the basket; and the dustproof assembly is arranged on the speaker inner frame. After the scheme is employed, the ceiling loudspeaker device can be efficiently assembled and disassembled without the aid of a mounting tool.

Abstract: A pontoon-type floating structure comprising an upper deck that is to be maintained above water level and that is to receive and support a load by the load resting thereon; and a horizontal array of chambers disposed underneath the upper deck, with the chambers providing a first set of chambers that provide the structure with buoyancy, and a second set of chambers with water having access thereto so that the second set of chambers, under steady state conditions, do not provide buoyancy.

Abstract: A portable device to help adults hold and support their infants is a semi-circular belt-shaped fabric product that is preferably well-padded with soft durable materials. It comprises a center portion connecting with a pair of arm-extended elements, a pair of shoulder straps, a body strap, a pair of hand-holders and a pair of locking strap systems. It is primarily used for training and assisting infants to walk during the early development stages and beyond. It also functions to minimize back strain on the child caregiver by eliminating back bending when holding a child who is a significantly different height. The design provides this device with the advantages of long-term usage and multiple functions, such as securing an infant onto a chair.

Abstract: A pontoon-type floating structure comprising an upper deck that is to be maintained above water level and that is to receive and support a load by the load resting thereon; and a horizontal array of chambers disposed underneath the upper deck, with the chambers providing a first set of chambers that provide the structure with buoyancy, and a second set of chambers with water having access thereto so that the second set of chambers, under steady state conditions, do not provide buoyancy.

Abstract: Disclosed is a portable device to help adults hold and support their infants without bending their backs. This safety device is a semi-circular belt-shaped fabric product that is preferably well-padded with soft durable materials. It is primarily used for training and assisting infants to walk during the early development stages and beyond. It also functions to minimize back strain on the child caregiver by eliminating back bending when holding a child who is a significantly different height. The revolutionary technical design allows this device to be simple to make and simple to use, with the advantages of long-term usage and multiple functions, such as securing an infant onto a chair. All of these features are lacking in similar products in the prior art.

Abstract: This invention relates to compositions and methods for the treatment of pathologies associated with intracellular polyamine dysregulation. In particular, the present invention provides compositions and methods involving mammalian polyamine oxidase (PAO) to treat cancer, cell damage, tissue damage caused by ischemia/reperfusion, inflammation, traumatic brain injury, stroke and tissue developmental disorders. Methods for diagnosis and prognosis of cancer and other diseases are also provided by the present invention.