Patents by Inventor Tibor Mathe

Tibor Mathe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5322698
    Abstract: The invention relates to a process for the preparation of a tablet or dragee composition containing a moisture-, heat- and light-sensitive compounds having monoclinic crystalline structure as active ingredients, which comprises homogenizing the active ingredient with 0.2 to 1.5 parts by weight of an anhydrous alkaline earth metal salt and 0.5 to 2.5 parts by weight of microcrystalline cellulose calculated for the active ingredient and optionally with one or more pharmaceutically acceptable carrier(s) and/or additive(s) and compressing the homogeneous mixture obtained to tablets in a manner known per se and, if desired, coating the tablet thus obtained in a manner known per se.
    Type: Grant
    Filed: June 5, 1992
    Date of Patent: June 21, 1994
    Assignee: Biogal Gyogyszergyar Rt.
    Inventors: Istvan Kovacs, Katalin Beke, Tibor Mathe, Judit Szilagyi, Gyorgy Bacsa, Katalin Marossy, Sandor Jancso, Levente Szendrei, Erno Orban, Margit Simo, Margit Biblo, Dorottya Bobak, Jozsef Lango
  • Patent number: 4361500
    Abstract: The invention relates to a new process for the preparation of a supported metal catalyst containing at least one metal belonging to Group A and optionally at least one metal belonging to Group B, wherein Group A encompasses the metals palladium, rhodium, ruthenium, platinum, iridium, osmium, silver, gold and cadmium and Group B encompasses the metals zinc, mercury, germanium, tin, antimony and lead. According to the invention, the metal(s) is (are) applied onto the support in the presence of at least one compound of the general formula (I), ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 each stands for a straight-chained or branched C.sub.1-20 alkyl group, a C.sub.1-4 hydroxyalkyl group or a phenyl-(C.sub.1-4 alkyl) group optionally having additional substituents, preferably C.sub.1-4 alkyl groups, on the phenyl ring, andX is hydroxy group or the residue of an organic or mineral acid.According to the invention, highly active catalysts can be prepared by an easy and economical process.
    Type: Grant
    Filed: May 18, 1981
    Date of Patent: November 30, 1982
    Assignee: Magyar Tudomanyos Akademia Kosponti Hivatala
    Inventors: Tibor Mathe, Antal Tungler, Jozsef Petro
  • Patent number: 4299992
    Abstract: The invention relates to a new process for the selective hydroxymethylation of substituted ortho- or paranitrotoluenes of the general formula (I) ##STR1## in order to prepare nitrophenylalkanols of the general formula (II) ##STR2## In the above formulae the nitro group is attached to the benzene ring in ortho or para position related to the methyl group or the hydroxyalkyl side chain, respectively, X stands for hydrogen, fluorine or an alkyl, alkoxy or nitro group, and n is 1, 2 or 3.According to the process of the invention the starting substance is hydroxymethylated with an excess of formaldehyde at a temperature above room temperature in dimethyl formamide and in the presence of a strong base. The reaction is performed in dimethyl formamide containing 0.1 to 1% by weight of water, and the reaction is directed to the formation of the required end-product by properly adjusting the temperature and the amount of formaldehyde and the base with respect to the starting compound of the general formula (I).
    Type: Grant
    Filed: May 20, 1980
    Date of Patent: November 10, 1981
    Assignees: Reanal Finomvegyszergyar, Budapesti Muszaki Egyetem
    Inventors: Antal Tungler, Tibor Mathe, Jozsef Petro, Zoltan Bende
  • Patent number: 4036877
    Abstract: The invention relates to a process for the preparation of aldehydes by hydrogenating carboxylic chlorides of the general formula RCOCl, wherein R stands for alkyl, isoalkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, aromatic, heterocyclic or substituted heterocyclic group, the substituents being alkyl, halogen, hydroxy, alkoxy, carboxyl, carbonyl and nitro groups wherein the hydrogenation is carried out in the presence of an alloy catalyst comprising at least one element of the platinum group and at least one element of the groups IB and IIB of the periodic system.The invention renders possible the production of aldehydes in a fair yield and at an adequate selectivity.
    Type: Grant
    Filed: February 12, 1975
    Date of Patent: July 19, 1977
    Assignee: Budapesti Muszaki Egyetem
    Inventors: Jozsef Petro, Tibor Mathe, Antal Tungler
  • Patent number: 4021374
    Abstract: The invention relates to novel selective hydrogenating catalysts comprising at least one platinum group component and at least one of a group IB or group IIB component. These catalysts are prepared by depositing and reducing an ion, complex or hydroxide of at least one metal belonging to the platinum group together with an ion, complex or hydroxide of at least one metal belonging to either of groups IB and IIB of the Periodic System.
    Type: Grant
    Filed: December 12, 1974
    Date of Patent: May 3, 1977
    Assignee: Magyar Tudomanyos Akademia Szerves Kemiai Technologiai Tanszek
    Inventors: Jozsef Petro, Tibor Mathe, Antal Tungler, Zoltan Csuros
  • Patent number: 4021371
    Abstract: The invention relates to a novel method of preparing catalysts containing the oxides and/or oxyhydrates of aluminum, silicon, magnesium or zinc either alone or in combination with each other, or catalysts containing a metal or a metal oxide as active component and an above-identified oxide and/or oxyhydrate or a mixture thereof as support. According to the invention catalysts with excellent activities can be prepared with a simple and economic operation.One proceeds, in accordance with the invention, as follows: powdered metallic aluminum, silicon, magnesium or zinc or a fused mixture thereof, or, when a supported catalyst is to be prepared, a fused mixture also containing one or more catalytically active metals, is admixed with an alkali metal hydroxide or carbonate or an alkaline earth metal hydroxide, said alkaline agent being used in an amount of 0.
    Type: Grant
    Filed: November 19, 1975
    Date of Patent: May 3, 1977
    Assignee: Budapesti Muszaki Egyetem
    Inventors: Jozsef Petro, Tibor Mathe, Antal Tungler