Abstract: The present invention relates to a catalytic process for the partial reduction of esters or lactones to silyl acetals, which upon hydrolysis give aldehydes, using silanes as reducing agents, preferably triethylsilane (TESH) or 1,1,3,3-tetramethyldisiloxane (TMDS), in the presence of novel triaryl borane type catalysts. More specifically, the present invention relates to novel triaryl borane type catalyst compounds of formula (I) which can be applied for the partial reduction of an ester or lactone to a silyl acetal. In the formula R1, R?1, R5, R?5 and R6 are groups having small steric demand and R10 is a group having large steric demand.

Abstract: wherein R1, R2, R3, R4, R5, n and Q are as defined in the description.

Abstract: The present invention is related to 8-hydroxy-quinoline derivatives having multidrug-resistance reversing activity with improved selectivity and increased cytotoxicity towards multidrug-resistant cancer cells, preparation thereof and use of the same in the treatment of cancer, especially multidrug-resistant variants thereof.

Abstract: The invention relates to palladium(0)-tris{tri-[3,5-bis(trifluoromethyl)-phenyl]-phosphine} complex of formula (I), as well as to its preparation and use. This compound is outstandingly stable, and can be used as catalyst with excellent results.