Patents by Inventor Tiechao Li

Tiechao Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Amidophenoxyindazoles useful as inhibitors of c-Met
    Patent number: 8030302
    Abstract: The present invention provides amidophenoxyindazole compounds useful in the treatment of cancer.
    Type: Grant
    Filed: July 15, 2009
    Date of Patent: October 4, 2011
    Assignee: Eli Lilly and Company
    Inventors: Tiechao Li, Mark Andrew Pobanz, Chuan Shih, Zhipei Wu, Wei Jennifer Yang, Boyu Zhong
  • Kinase inhibitors
    Patent number: 7767674
    Abstract: The present invention provides kinase inhibitors of Formula I:
    Type: Grant
    Filed: June 15, 2005
    Date of Patent: August 3, 2010
    Assignee: Eli Lilly and Company
    Inventors: Tiechao Li, Mark Andrew Pobanz, Chuan Shih, Yong Wang, Boyu Zhong, Jesus Andres Blas, Alfonso De Dios, Beatriz Lopez De Uralde-Garmendia, Luisa Maria Martin Cabrejas
  • AMIDOPHENOXYINDAZOLES USEFUL AS INHIBITORS OF C-MET
    Publication number: 20100022529
    Abstract: The present invention provides amidophenoxyindazole compounds useful in the treatment of cancer.
    Type: Application
    Filed: July 15, 2009
    Publication date: January 28, 2010
    Inventors: Tiechao LI, Mark Andrew POBANZ, Chuan SHIH, Zhipei WU, Wei Jennifer YANG, Boyu ZHONG
  • Kinase inhibitors
    Patent number: 7652015
    Abstract: The present invention provides kinase inhibitors of Formula (I). Wherein R1, R2, X and Z are as described herein, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: October 25, 2006
    Date of Patent: January 26, 2010
    Assignee: Eli Lilly and Company
    Inventors: Jolie Anne Bastian, Jesus Andres Blas de Blas, Alfonso De Dios, Kevin John Hudziak, Tiechao Li, Beatriz López De Uralde-Garmendia, Mary Margaret Mader, Michael Ray Myers, Mark Andrew Pobanz, Chuan Shih, Boyu Zhong
  • Kinase Inhibitors
    Publication number: 20080306068
    Abstract: The present invention provides kinase inhibitors of Formula I:
    Type: Application
    Filed: June 15, 2005
    Publication date: December 11, 2008
    Applicant: Eli Lilly and Company
    Inventors: Tiechao Li, Mark Andrew Pobanz, Chuan Shih, Yong Wang, Boyu Zhong, Jesus Andres Blas, Alfonso De Dios, Beatriz Lopez De Uralde-Garmendia, Luisa Maria Martin Cabrejas
  • Kinase Inhibitors
    Publication number: 20080269244
    Abstract: The present invention provides kinase inhibitors of Formula (I). Wherein R1, R2, X and Z are as described herein, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: October 25, 2006
    Publication date: October 30, 2008
    Inventors: Jolie Anne Bastian, Jesus Andres Blas de Blas, Alfonso De Dios, Kevin John Hudziak, Tiechao Li, Beatriz Lopez De Uralde-Garmendia, Mary Margaret Mader, Michael Ray Myers, Mark Andrew Pobanz, Chuan Shih, Boyu Zhong
  • Agents and methods for the treatment of proliferative diseases
    Patent number: 6867198
    Abstract: The present invention provides selective kinase inhibitors of formula (I)
    Type: Grant
    Filed: December 18, 2000
    Date of Patent: March 15, 2005
    Assignee: Eli Lilly and Company
    Inventors: Rima Salim Al-Awar, Kyle Andrew Hecker, James Edward Ray, Jianping Huang, Sajan Joseph, Tiechao Li, Michael Paal, Radhakrishnan Rathnachalam, Chuan Shih, Philip Parker Waid, Xun Zhou, Guoxin Zhu
  • Compounds useful in pain management
    Patent number: 6844368
    Abstract: The present invention relates to novel oxo-aminotetralin compounds of the formula (I) wherein X, R1, R2, R3, R4, R5, and R6 are defined herein. The compounds of formula (I) are useful in pain management.
    Type: Grant
    Filed: December 14, 1999
    Date of Patent: January 18, 2005
    Inventors: Edward Roberts, Tiechao Li, Dilip Dixit, Krzysztof Bednarski, Jean-Francois Lavallée, Dick Storer, Wuyi Wang
  • Agents and methods for the treatment of proliferative diseases
    Publication number: 20030229026
    Abstract: The present invention provides selective kinase inhibitors of formula (I).
    Type: Application
    Filed: December 2, 2002
    Publication date: December 11, 2003
    Inventors: Rima Salim Al-Awar, Kyle Andrew Hecker, James Edward Ray, Jianping Huang, Sajan Joseph, Tiechao Li, Michael Paal, Radhakrishnan Rathnachalam, Chuan Shih, Philip Parker Waid, Xun Zhou, Guoxin Zhu
  • Compounds useful in pain management
    Patent number: 6498196
    Abstract: The present invention relates to novel thio-aminotetralin compounds of the formula (I) wherein Z, X, R1, R2, R3, R4, R5, and R6 are defined herein. The compounds are useful in pain management.
    Type: Grant
    Filed: December 14, 1999
    Date of Patent: December 24, 2002
    Inventors: Edward Roberts, Tiechao Li, Dilip Dixit, Krzysztof Bednarski, Dick Storer, Wuyi Wang
  • Rhodamine derivatives for photodynamic therapy of cancer and in vitro purging of the leukemias
    Patent number: 5773460
    Abstract: The present invention relates to novel photoactivable rhodamine derivatives for enhancing high quantum-yield production and singlet oxygen generation upon irradiation with light while maintaining desirable differential retention of rhodamine between normal and cancer cells. Representative derivatives are2-(4,5-dibromo-6-amino-3-imino-3H-xanthen-9-yl)-benzoic acid methyl ester hydrochloride; 2-(4, 5-dibromo-6-amino-3-imino-3H-xanthen-9-yl)-benzoic acid ethyl ester hydrochloride; 2-(4,5-dibromo-6-amino-3-imino-3H-xanthen-9-yl)-benzoic acid octyl ester hydrochloride; 2-(4,5-dibromo-6-amino-3-imino-3H-xanthen-9-yl)-benzoic acid n-butyl ester hydrochloride; 2-(6-ethyl amino-3-ethyl imino-3H-xanthen-9-yl)-benzoic acid n-butyl ester hydrochloride; and photoactivable derivatives thereof.
    Type: Grant
    Filed: July 1, 1996
    Date of Patent: June 30, 1998
    Assignee: Universite De Montreal
    Inventors: Louis Gaboury, Luc Villeneuve, Richard Giasson, Tiechao Li, Ajay Kumar Gupta
  • Novel rhodamine derivatives for photodynamic therapy of cancer and in vitro purging of the leukemias
    Patent number: 5556992
    Abstract: The present invention relates to novel photoactivable rhodamine derivatives for enhancing high quantum-yield production and singlet oxygen generation upon irradiation with light while maintaining desirable differential retention of rhodamine between normal and cancer cells, said derivatives are selected from the group consisting of 4,5-dibromorhodamine 123 (2-(4,5-dibromo-6-amino-3-imino-3H-xanthen-9-yl)-benzoic acid methyl ester hydrochloride); 4, 5-dibromorhodamine 123 (2-(4,5-dibromo-6-amino-3-imino-3H-xanthen-9-yl)-benzoic acid ethyl ester hydrochloride); 4, 5-dibromorhodamine 123 (2-(4,5-dibromo-6-amino-3-imino-3H-xanthen-9-yl)-benzoic acid octhyl ester hydrochloride); 4,5-dibromorhodamine 110 n-butyl ester (2-(4,5-dibromo-6-amino-3-imino-3H-xanthen-9-yl)-benzoic acid n-butyl ester hydrochloride); Rhodamine B n-butyl ester (2-(6-ethyl amino-3-ethyl imino-3H-xanthen-9-yl)-benzoic acid n-butyl ester hydrochloride); and photoactivable derivatives thereof; whereby photoactivation of the derivatives induces c
    Type: Grant
    Filed: September 2, 1994
    Date of Patent: September 17, 1996
    Assignee: Universite de Montreal
    Inventors: Louis Gaboury, Luc Villeneuve, Richard Giasson, Tiechao Li, Ajay K. Gupta
  • Amidophenoxyindazoles useful as inhibitors of c-Met
    Patent number: RE43878
    Abstract: The present invention provides amidophenoxyindazole compounds useful in the treatment of cancer.
    Type: Grant
    Filed: December 8, 2011
    Date of Patent: December 25, 2012
    Assignee: Eli Lilly and Company
    Inventors: Tiechao Li, Mark Andrew Pobanz, Chuan Shih, Zhipei Wu, Wei Jennifer Yang, Boyu Zhong