Abstract: The present invention relates to the use of light-converting, colloidal, doped semiconductor nanocrystals to provide a new generation of high performance, low cost monochromatic and white light sources based on LEDs.

Abstract: The present invention relates to low reabsorbing semiconductor nanocrystals having, simultaneously, an emission center core surrounded by at least one absorbing shell capable of absorbing blue or purple light and a protective exterior shell. The emission center core is capable of emitting at least one different wavelength range of light. The low reabsorbing semiconductor nanocrystals demonstrate an absorbance ratio greater than or equal to 10. These low reabsorbing semiconductor nanocrystals can be used in optical applications, some of which can include, for example, light-emitting diodes, solid-state-lighting, solar cells, lasers, and biomedical tags.

Abstract: The present invention relates to semiconductor nanocrystals having, simultaneously, an emission center surrounded by at least one absorbing shell and a protective exterior shell.

Abstract: This invention relates to a method of making a composition comprising a colloid comprising particles having a colloidal silica core and a shell, said method comprising the steps of: simultaneously introducing into a vessel a first liquid stream containing silica core particles, a second liquid stream containing a polymer having amine functionalities; and a third liquid stream having a pH adjusting substance such that said vessel is maintained at a pH below 6.0, and followed by readjusting the pH of the colloid to a pH between about 7-10; the addition of a cross-linking reagent, and adjusting the pH of the colloid to approximately physiological conditions, wherein the core-shell colloid contains between 10 and 30 ?mol amine-monomer/m2 core surface area.

Abstract: The present invention relates to the use of light-converting, colloidal, doped semiconductor nanocrystals to provide a new generation of high performance, low cost monochromatic and white light sources based on LEDs.

Abstract: Disclosed in this specification is an aqueous dispersion for treating a textile. The dispersion generally includes surface-functionalized inorganic oxides in combination with a fluorochemical. Significantly lower concentrations of fluorochemicals are present in comparison to prior art dispersions.

Abstract: Disclosed are embodiments and methods relating to the treatment of textile, such as a textile substrate, with an aqueous dispersion of surface-functionalized particles and a fluorochemical, or a textile substrate treated with an aqueous dispersion of surface-functionalized particles, a fluorochemical, and a flame retardant chemical. Textiles treated in accordance with the disclosed embodiments (e.g., fluorine concentration of from 20 to 900 ppm) demonstrate an average burn rate less than about 4.0 inch/minute, and an average weight loss is less than about 40% of the original weight. During burning of the treated textile, flaming drips extinguish (on average) in less than about 2 seconds, or does not increase the peak heat release rate by more than about 70%, and the mass loss rate by more than about 50%.

Abstract: A nanoparticulate imaging probe with an oxide core, a biocompatible polymeric shell covalently attached to the oxide core, a dye, and a cleavable spacer that covalently binds the dye to the probe. When the spacer is cleaved, the dye is liberated from the probe. The emissions of the dye are quenched when the dye is bound to the probe and not quenched when the dye is liberated from the probe. The spacer can be, for example, a peptide. The oxide core can be, for example, a silicon oxide core.

Abstract: The invention relates to a composition comprising a colloid which is stable under physiological pH and ionic strength, said colloid comprising particles having a silica core and a shell: a) wherein said shell comprises a cross-linked poly(ethylene)imine polymer having amine functionalities; b) wherein the particles have a volume-weighted mean particle size diameter of less than 200 nm, and c) wherein greater than 50% of said polymer in the colloid is bound to the core surfaces, wherein the polymer having amine functionalities has an average molecular weight less than 100,000 g/mol, the composition has a H of between 6 and 8; and d) wherein the colloid contains between 300 and 6000 .?mol amine-monomer/g core particles.

Abstract: A nanoparticulate imaging probe with an oxide core, a biocompatible polymeric shell covalently attached to the oxide core, a dye, and a cleavable spacer that covalently binds the dye to the probe. When the spacer is cleaved, the dye is liberated from the probe. The emissions of the dye are quenched when the dye is bound to the probe and not quenched when the dye is liberated from the probe. The spacer can be, for example, a peptide. The oxide core can be, for example, a silicon oxide core.

Abstract: Disclosed in this specification is an aqueous dispersion for treating a textile. The dispersion generally includes surface-functionalized inorganic oxides in combination with a fluorochemical. Significantly lower concentrations of fluorochemicals are present in comparison to prior art dispersions.

Abstract: There are disclosed colloids containing polymer-modified core-shell particle carrier. The described colloids containing core-shell nanoparticulate carrier particles wherein the shell contains a polymer having amine functionalities. The described carrier particles are stable under physiological conditions. The carriers can be bioconjugated with biological, pharmaceutical or diagnostic components.

Abstract: A coating composition for making a protein microarray, the composition comprising a gelling agent or a precursor to a gelling agent, and microspheres; the microspheres containing a dye represented by the Formula (1): wherein: R1=one or more substitutent selected from the group of H, chloro, alkoxycarbonyl, arylsulfamoyl, or alkylsulfamoyl; R2=one or more substituent selected from the group of H, carboxamido, or alkoxycarbonyl; R3=one or more substituent selected from the group of H, chloro, substituted or unsubstituted alkyl, aryl, carboxamido, or alkoxycarbonyl.

Abstract: The present invention relates to a method of detecting nucleic acids comprising suspending at least one recognizable target nucleic acid in a suspending solution containing polymeric particles marked with a probe, wherein the probe has an affinity for the target nucleic acid, adding a recognition unit-peroxidase conjugate marker to the suspending solution, forming a complex of the polymeric particles marked with a probe, the target nucleic acid and the recognition unit-peroxidase conjugate marker, contacting the suspending solution with a gelatin surface, adding a developer to the suspending solution in contact with the gelatin surface in the presence of phenol to attach the complex to the gelatin surface, washing the gelatin surface, and detecting the complex attached to the gelatin surface.

Abstract: A coating composition for making a protein microarray, the composition comprising a gelling agent or a precursor to a gelling agent and microspheres; the microspheres containing a dye represented by Formula (I): wherein: R1 and R2 independently represent substituted or unsubstituted alkyl, aryl, carbocyclic ring, heterocyclic ring, or amino; and R3 represents H, alkylamino, dialkylamino, hydroxy, or alkoxy.

Abstract: A composition comprising a colloid that is stable under physiological pH and ionic strength is disclosed. The colloid comprises particles having a core and a shell: a) wherein said shell comprises a silylamine coupling agent; b) wherein the particles have a volume-weighted mean particle size diameter of less than 200 nm, and c) wherein greater than 35% of said silylamine coupling agent present in the colloid is bound to the core surfaces. These core-shell nanoparticulate materials are capable of carrying biological, pharmaceutical or diagnostic components. The components, which might include drugs, therapeutics, diagnostics, and targeting moieties can then be delivered directly to diseased tissue or bones and be released in close proximity to the disease and reduce the risk of side effects to the patient.

Abstract: The present invention relates to a nanogel comprising a polymer network of repetitive, crosslinked, ethylenically unsaturated monomers of Formula I: (X)m-(Y)n-(Z)o??Formula I wherein X is a water-soluble monomer containing ionic or hydrogen bonding moieties; Y is a water-soluble macromonomer containing repetitive hydrophilic units bound to a polymerizeable ethylenically unsaturated group; Z is a multifunctional crosslinking monomer; m ranges from 50-90 mol %; n ranges from 2-30 mol %; and o range from 1-15 mol % and a method for preparing a nanogel comprising preparing a header composition of a mixture of monomers X, Y, and Z, and a first portion of initiators in water; preparing a reactor composition of a second portion initiators, surfactant, and water; bringing the reactor composition to the polymerization temperature; holding the reactor composition at the polymerization temperature, and adding the header composition to the reactor composition to form a nanogel of Formula I.

Abstract: The present invention relates to a method of detecting biological analytes comprising suspending a target analyte in a suspending solution containing polymeric particles marked with a probe, wherein the probe has an affinity for said target analyte; adding recognition unit-peroxidase conjugate marker to the suspending solution; forming a complex of the target analyte, the polymeric particles marked with a probe, and the recognition unit-peroxidase conjugate marker; contacting a gelatin surface with the suspending solution; adding developer to the suspending solution in contact with the gelatin surface in the presence of phenol to attach the complex to the gelatin surface; washing the gelatin surface; and detecting the complex attached to the gelatin surface.

Abstract: The present invention relates to a polymer particles comprising a polymer bead stabilized by vinylsulfonyl-functionalized polymers grafted to the surface of the bead, as well as a particle composition comprising monodisperse polymer beads stabilized by vinylsulfonyl-functionalized polymers, wherein the vinylsulfonyl-functionalized polymers are grafted to the surfaces of the beads. The invention also includes a method of preparing monodisperse polymer particles comprising preparing a homogeneous solution of an ethylenically unsaturated polymerizable monomer, an initiator, and a polymeric stabilizer, wherein the polymeric stabilizer consists of repetitive units, wherein the repetitive units comprise latent vinylsulfonyl moiety, polymerizing the homogeneous solution, and converting the latent vinylsulfonyl moiety to vinylsulfonyl moieties.

Abstract: There are disclosed colloids containing polymer-modified core-shell particle carrier. The described colloids containing core-shell nanoparticulate carrier particles wherein the shell contains a polymer having amine functionalities. The described carrier particles are stable under physiological conditions. The carriers can be bioconjugated with biological, pharmaceutical or diagnostic components.