Patents by Inventor Tien-Soung Tong
Tien-Soung Tong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11311592Abstract: Disclosed herein is the novel use of use of a Bauhinia spp. extract, which may upregulate neprilysin, induce autophagy, protect neuron from amyloidopathy or tauopathy, and/or promote neurite outgrowth, thus the Bauhinia spp. extract of the present disclosure may be used as a dietary supplement for the prophylaxis or treatment of amyloid related neurodegenerative diseases so as to ameliorate or alleviate symptoms associated with the amyloid related neurodegenerative diseases.Type: GrantFiled: February 24, 2020Date of Patent: April 26, 2022Assignees: ACADEMIA SINICA, INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Chang-Jen Huang, Rita P.-Y. Chen, Yung-Feng Liao, Bo-Kai Wu, Po-Ting Chen, Hui-Ping Tsai, Yi-Cheng Cheng, Cheng-Li Fang, Hung-Chi Chien, Tien-Soung Tong, Ting-Shou Chen, Shu-Jiau Chiou
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Publication number: 20200246410Abstract: Disclosed herein is the novel use of use of a Bauhinia spp. extract, which may upregulate neprilysin, induce autophagy, protect neuron from amyloidopathy or tauopathy, and/or promote neurite outgrowth, thus the Bauhinia spp. extract of the present disclosure may be used as a dietary supplement for the prophylaxis or treatment of amyloid related neurodegenerative diseases so as to ameliorate or alleviate symptoms associated with the amyloid related neurodegenerative diseases.Type: ApplicationFiled: February 24, 2020Publication date: August 6, 2020Inventors: Chang-Jen HUANG, Rita P.-Y. CHEN, Yung-Feng LIAO, Bo-Kai WU, Po-Ting CHEN, Hui-Ping TSAI, Yi-Cheng CHENG, Cheng-Li FANG, Hung-Chi CHIEN, Tien-Soung TONG, Ting-Shou CHEN, Shu-Jiau CHIOU
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Patent number: 10610557Abstract: Disclosed herein is the novel use of use of a Bauhinia spp. extract, which may upregulate neprilysin, induce autophagy, protect neuron from amyloidopathy or tauopathy, and/or promote neurite outgrowth, thus the Bauhinia spp. extract of the present disclosure may be used as a dietary supplement for the prophylaxis or treatment of amyloid related neurodegenerative diseases so as to ameliorate or alleviate symptoms associated with the amyloid related neurodegenerative diseases.Type: GrantFiled: November 3, 2016Date of Patent: April 7, 2020Assignees: ACADEMIA SINICA, INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Chang-Jen Huang, Rita P.-Y. Chen, Yung-Feng Liao, Bo-Kai Wu, Po-Ting Chen, Hui-Ping Tsai, Yi-Cheng Cheng, Cheng-Li Fang, Hung-Chi Chien, Tien-Soung Tong, Ting-Shou Chen, Shu-Jiau Chiou
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Publication number: 20180318371Abstract: Disclosed herein is the novel use of use of a Bauhinia spp. extract, which may upregulate neprilysin, induce autophagy, protect neuron from amyloidopathy or tauopathy, and/or promote neurite outgrowth, thus the Bauhinia spp. extract of the present disclosure may be used as a dietary supplement for the prophylaxis or treatment of amyloid related neurodegenerative diseases so as to ameliorate or alleviate symptoms associated with the amyloid related neurodegenerative diseases.Type: ApplicationFiled: November 3, 2016Publication date: November 8, 2018Inventors: Chang-Jen HUANG, Rita P.-Y. CHEN, Yung-Feng LIAO, Bo-Kai WU, Po-Ting CHEN, Hui-Ping TSAI, Yi-Cheng CHENG, Cheng-Li FANG, Hung-Chi CHIEN, Tien-Soung TONG, Ting-Shou CHEN, Shu-Jiau CHIOU
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Patent number: 9682062Abstract: The disclosure provides a pharmaceutical composition for inhibiting angiogenesis, including an effective amount of an extract of Juniperus chinensis or an effective amount of a lignan as an effective ingredient. The pharmaceutical composition may further include a pharmaceutically acceptable carrier or salt. The disclosure also provides a method for inhibiting angiogenesis, including administering an effective amount of an extract of Juniperus chinensis or an effective amount of a lignan as an effective ingredient for inhibiting angiogenesis to a subject in need thereof.Type: GrantFiled: December 18, 2013Date of Patent: June 20, 2017Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: I-Horng Pan, Hsin-Jan Yao, Mei-Wei Lin, I-Huang Lu, Hsin-Chieh Wu, Hsiang-Wen Tseng, Ching-Huai Ko, Chun-Chung Wang, Zong-Keng Kuo, Shyh-Horng Lin, Yi-Cheng Cheng, Tien-Soung Tong
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Patent number: 9549958Abstract: An extract of Cynanchum sp. in use of arthritis treatment is provided. The extract of Cynanchum sp. and an active ingredient contained therein, antofine, are applicable to a method, pharmaceutical composition and dietary supplement for treatment of arthritis. A mass production of antofine from plant extracts is also provided.Type: GrantFiled: April 27, 2012Date of Patent: January 24, 2017Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Jennline Sheu, Lain-Tze Lee, Ying-Chu Shih, Cheng-Yu Lee, Yi-Ching Lee, Jir-Mehng Lo, Tien-Soung Tong, Jui-Hung Yen, Kuo-Kuei Huang, Ying-Fei Tsai
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Publication number: 20160008319Abstract: The disclosure provides a pharmaceutical composition for inhibiting angiogenesis, including an effective amount of a lignan as an effective ingredient. The pharmaceutical composition may further include a pharmaceutically acceptable carrier or salt. The disclosure also provides a method for inhibiting angiogenesis, including administering an effective amount of a lignan as an effective ingredient for inhibiting angiogenesis to a subject in need thereof.Type: ApplicationFiled: September 24, 2015Publication date: January 14, 2016Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: I-Horng PAN, Hsin-Jan YAO, Mei-Wei LIN, I-Huang LU, Hsin-Chieh WU, Hsiang-Wen TSENG, Ching-Huai KO, Chun-Chung WANG, Zong-Keng KUO, Shyh-Horng LIN, Yi-Cheng CHENG, Tien-Soung TONG
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Patent number: 9060989Abstract: A method for treating or relieving inflammatory bowel disease (IBD) is provided, including administering an extract of Bupleurum as an active ingredient to a subject. The Bupleurum may be selected from the group consisting of Bupleurum krylovianum, Bupleurum chinense, Bupleurum commelynoideum, Bupleurum scorzonerifolium, Bupleurum triradiatum, Bupleurum falcatum, Bupleurum kaoi and a combination thereof.Type: GrantFiled: September 28, 2012Date of Patent: June 23, 2015Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Ying-Chu Shih, Lain-Tze Lee, Nai-Yun Hu, Tien-Soung Tong
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Publication number: 20140170250Abstract: The disclosure provides a pharmaceutical composition for inhibiting angiogenesis, including an effective amount of an extract of Juniperus chinensis or an effective amount of a lignan as an effective ingredient. The pharmaceutical composition may further include a pharmaceutically acceptable carrier or salt. The disclosure also provides a method for inhibiting angiogenesis, including administering an effective amount of an extract of Juniperus chinensis or an effective amount of a lignan as an effective ingredient for inhibiting angiogenesis to a subject in need thereof.Type: ApplicationFiled: December 18, 2013Publication date: June 19, 2014Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: I-Horng PAN, Hsin-Jan YAO, Mei-Wei LIN, I-Huang LU, Hsin-Chieh WU, Hsiang-Wen TSENG, Ching-Huai KO, Chun-Chung WANG, Zong-Keng KUO, Shyh-Horng LIN, Yi-Cheng CHENG, Tien-Soung TONG
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Publication number: 20140134280Abstract: An extract of Cynanchum sp. in use of arthritis treatment is provided. The extract of Cynanchum sp. and an active ingredient contained therein, antofine, are applicable to a method, pharmaceutical composition and dietary supplement for treatment of arthritis. A mass production of antofine from plant extracts is also provided.Type: ApplicationFiled: April 27, 2012Publication date: May 15, 2014Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Jennline Sheu, Lain-Tze Lee, Ying-Chu Shih, Cheng-Yu Lee, Yi-Ching Lee, Jir-Mehng Lo, Tien-Soung Tong, Jui-Hung Yen, Kuo-Kuei Huang, Ying-Fei Tsai
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Patent number: 8597693Abstract: A pharmaceutical composition with an immunomodulating function is provided, including an extract of Bupleurum obtained by grinding the Bupleurum, adding the ground Bupleurum to a solvent and isolating the extract from the solvent, wherein the Bupleurum comprises Bupleurum krlovianum, Bupleurum longiradiatum, Bupleurum smithii, Bupleurum pusillum, Bupleurum longicaule, Bupleurum salicifolium, Bupleurum scorzonerifolium and Bupleurums with at least one of the nucleotide sequences selected from a group consisting of SEQ ID NOs. 1˜6 and a nucleotide sequence with no more than 1% of the nucleotide sequence divergences of SEQ ID NOs. 1˜6, or combinations thereof.Type: GrantFiled: July 1, 2010Date of Patent: December 3, 2013Assignee: Industrial Technology Research InstituteInventors: Ying-Chu Shih, Lain-Tze Lee, Bie-Shung Tsai, Jir-Mehng Lo, Tien-Soung Tong, Jenn-Line Sheu, Kuo-Kuei Huang, Ying-Fei Tsai, Yi-Ching Lee, Hui-Ju Liang, Jui-Hung Yen, Cheng-Yu Lee
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Publication number: 20120003342Abstract: A pharmaceutical composition for treating or relieving inflammatory bowel disease (IBD) is provided. The pharmaceutical composition includes an extract of Bupleurum as an active ingredient, in which the Bupleurum is selected from the group consisting of Bupleurum krylovianum, Bupleurum chinense, Bupleurum commelynoideum, Bupleurum scorzonerifolium, Bupleurum triradiatum, Bupleurum falcatum, Bupleurum kaoi and a combination thereof.Type: ApplicationFiled: May 28, 2011Publication date: January 5, 2012Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Ying-Chu Shih, Lain-Tze Lee, Nai-Yun Hu, Tien-Soung Tong
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Publication number: 20120003250Abstract: A pharmaceutical composition with an immunomodulating function is provided, including an extract of Bupleurum obtained by grinding the Bupleurum, adding the ground Bupleurum to a solvent and isolating the extract from the solvent, wherein the Bupleurum comprises Bupleurum krlovianum, Bupleurum longiradiatum, Bupleurum smithii, Bupleurum pusillum, Bupleurum longicaule, Bupleurum salicifolium, Bupleurum scorzonerifolium and Bupleurums with at least one of the nucleotide sequences selected from a group consisting of SEQ ID NOs. 1˜6 and a nucleotide sequence with no more than 1% of the nucleotide sequence divergences of SEQ ID NOs. 1˜6, or combinations thereof.Type: ApplicationFiled: July 1, 2010Publication date: January 5, 2012Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Ying-Chu Shih, Lain-Tze Lee, Bie-Shung Tsai, Jir-Mehng Lo, Tien-Soung Tong, Jenn-Line Sheu, Kuo-Kuei Huang, Ying-Fei Tsai, Yi-Ching Lee, Hui-Ju Liang, Jui-Hung Yen, Cheng-Yu Lee
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Publication number: 20050136142Abstract: An extract for treating hepatitis extracted from the roots or stems of Urticaceae by organic solvents is disclosed. The Urticaceae used in the present invention has a unique sequence of internal transcribed spacer of rDNA, which is at least 70% sequence similarity with that of Boehmeria frutescens, Boehmeria zollingeriana, Urlica thunbergiana, Pilea spp., Boehmeria nivea or Boehmeria densiflora. The extract of the present invention can inhibit the DNA replication of both the wild type hepatitis B virus and the lamivudine-resistant hepatitis B virus.Type: ApplicationFiled: August 11, 2004Publication date: June 23, 2005Applicant: Industrial Technology Research InstituteInventors: Lain-Tze Lee, Shau-Feng Chang, Cheng-Yu Lee, Shu-Jiau Chiou, Tien-Soung Tong