Abstract: The disclosure relates to systems and methods for accurate generation of material maps of volume of interests, for example, that include implants, for proton radiation therapy. In one implementation, the method may include determining most probable energy (MPE) using particle energy determined from particle counting data. The method may include generating a plurality of simulations that simulate interactions using different combination of properties for the volume of interest determined from representation data and/or from a database to determine most probable energy (MPE) for each simulation. The method may include comparing the MPE determined using the particle counting data to the MPE determined from each simulation. The method may further include selecting one simulation of the plurality of simulations based on the comparing. The method may also include generating a material map for the volume of interest using the one or more properties corresponding to the one simulation.

Abstract: A CT scanning method compensates gantry motion blurring in projection measurement based on synchronized focal spot movement and detector data shifting. Tube power is increased by moving the focal on the target and reducing focal spot dwell duration. The CT scanning method is used on helical CT and cone beam with a rotating anode source and CBCT and TBCT with a linear array x-ray source.

Abstract: A multi-pixel x-ray source is provided. The x-ray source includes a plurality of transmission target assemblies. The transmission target assembly includes a tungsten target and a diamond substrate. The substrate includes a first transmission surface and a second transmission surface opposite first transmission surface. The substrate further includes a first side surface and a second side surface disposed between the first and second transmission surfaces. The target covers the first transmission surface of the substrate. The transmission target assembly further includes a base. The base surrounds the first and second side surfaces of substrate, exposing a collimator surface of the second transmission surface and the target. The transmission target assembly is configured to transmit x-ray generated by the target through the target and the substrate.

Abstract: A multi-pixel x-ray source is provided. The x-ray source includes a plurality of transmission target assemblies. The transmission target assembly includes a tungsten target and a diamond substrate. The substrate includes a first transmission surface and a second transmission surface opposite first transmission surface. The substrate further includes a first side surface and a second side surface disposed between the first and second transmission surfaces. The target covers the first transmission surface of the substrate. The transmission target assembly further includes a base. The base surrounds the first and second side surfaces of substrate, exposing a collimator surface of the second transmission surface and the target. The transmission target assembly is configured to transmit x-ray generated by the target through the target and the substrate.

Abstract: A system or method for radiation treatment optimized for non-coplanar delivery, which includes a first collimator affixed to a gantry and a second collimator movably attached to the gantry to provide the second collimator a translation movement out of a gantry rotation plane. The system or method also includes a third collimator configured to collimate the beam in a direction of a target in the patient's body. The beam collimated by the third collimator is configured to follow the target during treatment. A method of performing rotation setup correction by rotating the treatment beam, without rotating the patient.

Abstract: A multi-pixel x-ray source is provided. The x-ray source includes a plurality of transmission target assemblies. The transmission target assembly includes a tungsten target and a diamond substrate. The substrate includes a first transmission surface and a second transmission surface opposite first transmission surface. The substrate further includes a first side surface and a second side surface disposed between the first and second transmission surfaces. The target covers the first transmission surface of the substrate. The transmission target assembly further includes a base. The base surrounds the first and second side surfaces of substrate, exposing a collimator surface of the second transmission surface and the target. The transmission target assembly is configured to transmit x-ray generated by the target through the target and the substrate.

Abstract: A system or method for radiation treatment optimized for non-coplanar delivery, which includes a first collimator affixed to a gantry and a second collimator movably attached to the gantry to provide the second collimator a translation movement out of a gantry rotation plane. The system or method also includes a third collimator configured to collimate the beam in a direction of a target in the patient's body. The beam collimated by the third collimator is configured to follow the target during treatment. A method of performing rotation setup correction by rotating the treatment beam, without rotating the patient.

Abstract: A radiation treatment and imaging system for emitting a radiation treatment beam and X-ray imaging beams towards an object. The system includes an x-ray source and a collimator, first and second detectors, and a linear accelerator that delivers radiation beams to an object. The linear accelerator includes a radiation source positioned between the first and second detectors and emitting a therapy radiation beam in-line with the x-ray beams received by the first and second detectors. The system also includes a data processing device in communication with the first and second detectors. The data processing device receives imaging signals from the first and second detectors and reconstructs a three-dimensional tetrahedron beam computed tomography (TBCT) image from the received imaging signals. The system also includes a display in communication with the data processing device and for displaying the TBCT image.

Abstract: A tetrahedron beam computed tomography system including an x ray source array that sequentially emits a plurality of x ray beams at different positions along a scanning direction and a collimator that intercepts the plurality of x-ray beams so that a plurality of fan-shaped x-ray beams emanate from the collimator towards an object. The system includes a first detector receiving a first set of fan-shaped x ray beams after they pass through the object, the first detector generating a first imaging signal for each of the received first set of fan-shaped x-ray beams and a second detector receiving a second set of fan-shaped x ray beams after they pass through the object, the second detector generating a second imaging signal for each of the received second set of fan-shaped x-ray beams. Each detector and source pair form a tetrahedral volume. In other embodiments, the system may also have more than two detectors arrays and/or more than one source array.

Abstract: A tetrahedron beam computed tomography system including an x ray source array that sequentially emits a plurality of x ray beams at different positions along a scanning direction and a collimator that intercepts the plurality of x-ray beams so that a plurality of fan-shaped x-ray beams emanate from the collimator towards an object. The system includes a first detector receiving a first set of fan-shaped x ray beams after they pass through the object, the first detector generating a first imaging signal for each of the received first set of fan-shaped x-ray beams and a second detector receiving a second set of fan-shaped x ray beams after they pass through the object, the second detector generating a second imaging signal for each of the received second set of fan-shaped x-ray beams. Each detector and source pair form a tetrahedral volume. In other embodiments, the system may also have more than two detectors arrays and/or more than one source array.

Abstract: A radiation treatment and imaging system for emitting a radiation treatment beam and X-ray imaging beams towards an object. The system includes an x-ray source and a collimator, first and second detectors, and a linear accelerator that delivers radiation beams to an object. The linear accelerator includes a radiation source positioned between the first and second detectors and emitting a therapy radiation beam in-line with the x-ray beams received by the first and second detectors. The system also includes a data processing device in communication with the first and second detectors. The data processing device receives imaging signals from the first and second detectors and reconstructs a three-dimensional tetrahedron beam computed tomography (TBCT) image from the received imaging signals. The system also includes a display in communication with the data processing device and for displaying the TBCT image.

Abstract: A tetrahedron beam computed tomography system including an x ray source array that sequentially emits a plurality of x ray beams at different positions along a scanning direction and a collimator that intercepts the plurality of x-ray beams so that a plurality of fan-shaped x-ray beams emanate from the collimator towards an object. The system includes a first detector receiving a first set of fan-shaped x ray beams after they pass through the object, the first detector generating a first imaging signal for each of the received first set of fan-shaped x-ray beams and a second detector receiving a second set of fan-shaped x ray beams after they pass through the object, the second detector generating a second imaging signal for each of the received second set of fan-shaped x-ray beams. Each detector and source pair form a tetrahedral volume. In other embodiments, the system may also have more than two detectors arrays and/or more than one source array.

Abstract: A method of imaging an object that includes directing a plurality of x-ray beams in a fan-shaped form towards an object, detecting x-rays that pass through the object due to the directing a plurality of x-ray beams and generating a plurality of imaging data regarding the object from the detected x-rays. The method further includes forming either a three-dimensional cone-beam computed tomography, digital tomosynthesis or Megavoltage image from the plurality of imaging data and displaying the image.

Abstract: A tetrahedron beam computed tomography system including an x ray source array that sequentially emits a plurality of x ray beams at different positions along a scanning direction and a collimator that intercepts the plurality of x-ray beams so that a plurality of fan-shaped x-ray beams emanate from the collimator towards an object. The system includes a first detector receiving a first set of fan-shaped x ray beams after they pass through the object, the first detector generating a first imaging signal for each of the received first set of fan-shaped x-ray beams and a second detector receiving a second set of fan-shaped x ray beams after they pass through the object, the second detector generating a second imaging signal for each of the received second set of fan-shaped x-ray beams. Each detector and source pair form a tetrahedral volume. In other embodiments, the system may also have more than two detectors arrays and/or more than one source array.

Abstract: A method of imaging an object that includes directing a plurality of x-ray beams in a fan-shaped form towards an object, detecting x-rays that pass through the object due to the directing a plurality of x-ray beams and generating a plurality of imaging data regarding the object from the detected x-rays. The method further includes forming either a three-dimensional cone-beam computed tomography, digital tomosynthesis or Megavoltage image from the plurality of imaging data and displaying the image.

Abstract: Radiation treatment of the lung or surrounding tissue during continuous breathing is made possible by preparing a treatment plan linked to motion phase and then synchronizing the plan to motion phase as the patient follows a regular breathing schedule.

Abstract: A method of imaging an object that includes directing a plurality of x-ray beams in a fan-shaped form towards an object, detecting x-rays that pass through the object due to the directing a plurality of x-ray beams and generating a plurality of imaging data regarding the object from the detected x-rays. The method further includes forming either a three-dimensional cone-beam computed tomography, digital tomosynthesis or Megavoltage image from the plurality of imaging data and displaying the image.

Abstract: An improved non-invasive respiration monitor combines signals from a spirometer and laser chest displacement sensor to reduce signal error. The improved respirations signal can be used for position correction in radiation therapy and imaging applications and can be displayed to a user in breath control techniques.

Abstract: A method of imaging an object that includes directing a plurality of x-ray beams in a fan-shaped form towards an object, detecting x-rays that pass through the object due to the directing a plurality of x-ray beams and generating a plurality of imaging data regarding the object from the detected x-rays. The method further includes forming either a three-dimensional cone-beam computed tomography, digital tomosynthesis or Megavoltage image from the plurality of imaging data and displaying the image.

Abstract: Radiation treatment of the lung or surrounding tissue during continuous breathing is made possible by preparing a treatment plan linked to motion phase and then synchronizing the plan to motion phase as the patient follows a regular breathing schedule.