Patents by Inventor Tiffany Leidy-Davis

Tiffany Leidy-Davis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LARGE GENOMIC DNA KNOCK-IN AND USES THEREOF
    Publication number: 20180355382
    Abstract: The present invention provides compositions and methods for utilizing a large capacity cloning vector (e.g., BAC) to carry a large exogenous genomic DNA (about 10-300 kb) flanked by a proximal and distal regions (10 kb) to efficiently insert into the genome of a cell in a CRISPR/Cas9-stimulated homologous recombination. Methods and compositions for microinjecting a large human gene into a mouse zygote to prepare a genetically modified mouse are also provided.
    Type: Application
    Filed: May 2, 2018
    Publication date: December 13, 2018
    Inventors: David Bergstrom, Tiffany Leidy-Davis