Patents by Inventor Tiina L. Hurskainen

Tiina L. Hurskainen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleic acids encoding zinc metalloproteases
    Publication number: 20020110894
    Abstract: Isolated mammalian proteins having disintegrin-like and metalloprotease domains with thrombospondin type I motifs, i.e., ADAMTS proteins, are provided. The proteins are ADAMTS-5, ADAMTS-6, ADAMTS-7, ADAMTS-8, ADAMTS-9 and ADAMTS-10, collectively referred to as 5 “ADAMTS-N”. The present invention also provides isolated polynucleotides which encode an ADAMTS-N protein or a variant thereof, polynucleotide sequences complementary to such polynucleotides, vectors containing such polynucleotides, and host cells transformed or transfected with such vectors. The present invention also relates to antibodies which are immunospecific for one or more of the ADAMTS-N proteins. The present invention also relates to a protein referred to hereinafter as ADAMTS-R1 (ADAM-TS Related protein-1) and the polynucleotides which encode such protein.
    Type: Application
    Filed: July 30, 2001
    Publication date: August 15, 2002
    Inventors: Suneel S. Apte, Tiina L. Hurskainen, Satoshi Hirohata
  • Nucleic acids encoding zinc metalloproteases
    Patent number: 6391610
    Abstract: Isolated mammalian proteins having disintegrin-like and metalloprotease domains with thrombospondin type I motifs, i.e., ADAMTS proteins, are provided. The proteins are ADAMTS-5, ADAMTS-6, ADAMTS-7, ADAMTS-8, ADAMTS-9 and ADAMTS-10, collectively referred to as “ADAMTS-N”. The present invention also provides isolated polynucleotides which encode an ADAMTS-N protein or a variant thereof, polynucleotide sequences complementary to such polynucleotides, vectors containing such polynucleotides, and host cells transformed or transfected with such vectors. The present invention also relates to antibodies which are immunospecific for one or more of the ADAMTS-N proteins. The present invention also relates to a protein referred to hereinafter as ADAMTS-R1 (ADAM-TS Related protein-1) and the polynucleotides which encode such protein.
    Type: Grant
    Filed: August 6, 1999
    Date of Patent: May 21, 2002
    Assignee: The Cleveland Clinic Foundation
    Inventors: Suneel S. Apte, Tiina L. Hurskainen, Satoshi Hirohata