Patents by Inventor Tiina Nakari-Setala

Tiina Nakari-Setala has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10072279
    Abstract: The present invention concerns a method for producing terpenes in fungi comprising the steps of (a) providing a modified terpene biosynthetic gene cluster inside a host cell, wherein one or more of the naturally occurring genes or promoters of the cluster have been replaced, truncated or removed, (b) providing a transcription factor inside the host cell, the transcription factor activating the terpene biosynthetic gene cluster; (c) cultivating said host in conditions allowing the expression of the transcription factor activating the cluster; and optionally (d) recovering the thus produced terpene product.
    Type: Grant
    Filed: May 13, 2013
    Date of Patent: September 11, 2018
    Assignee: Teknologian tutkimuskeskus VTT Oy
    Inventors: Kirsi Bromann, Mervi Toivari, Tiina Nakari-Setälä, Laura Ruohonen
  • Patent number: 9783793
    Abstract: The present invention relates to novel polypeptides, or fragments of polypeptides, genes encoding them and means for producing said polypeptides. In detail the invention relates to polypeptides having esterase, suberinase and/or cutinase activity at low pH. This invention relates also to compositions containing the polypeptides and methods of using the polypeptides.
    Type: Grant
    Filed: April 11, 2012
    Date of Patent: October 10, 2017
    Assignee: Teknologian Tutkimuskeskus VTT
    Inventors: Antti Nyyssola, Hanna Kontkanen, Mari Hakkinen, Ville Pihlajaniemi, Markku Saloheimo, Johanna Buchert, Tiina Nakari-Setala
  • Publication number: 20160194674
    Abstract: The present invention concerns a method for producing terpenes in fungi comprising the steps of (a) providing a modified terpene biosynthetic gene cluster inside a host cell, wherein one or more of the naturally occurring genes or promoters of the cluster have been replaced, truncated or removed, (b) providing a transcription factor inside the host cell, the transcription factor activating the terpene biosynthetic gene cluster; (c) cultivating said host in conditions allowing the expression of the transcription factor activating the cluster; and optionally (d) recovering the thus produced terpene product.
    Type: Application
    Filed: May 13, 2013
    Publication date: July 7, 2016
    Applicant: Teknologian tutkimuskeskus VTT
    Inventors: Kirsi Bromann, Mervi Toivari, Tiina Nakari-Setälä, Laura Ruohonen
  • Publication number: 20150225314
    Abstract: A method for the manufacture of aromatic hydrocarbons, includes allowing at least one olefin to react with at least one hydrogen scavenger at a temperature from 50 to 1000° C., under a pressure from normal atmospheric pressure to 500 bar without an added catalyst, to yield aromatic hydrocarbons.
    Type: Application
    Filed: September 13, 2013
    Publication date: August 13, 2015
    Inventors: Martta Asikainen, Olli Aaltonen, Ali Harlin, Tiina Nakari-Setala
  • Publication number: 20140234921
    Abstract: The present invention relates to novel polypeptides, or fragments of polypeptides, genes encoding them and means for producing said polypeptides. In detail the invention relates to polypeptides having esterase, suberinase and/or cutinase activity at low pH. This invention relates also to compositions containing the polypeptides and methods of using the polypeptides.
    Type: Application
    Filed: April 11, 2012
    Publication date: August 21, 2014
    Applicant: TEKNOLOGIAN TUTKIMUSKESKUS VTT
    Inventors: Antti Nyyssola, Hanna Kontkanen, Mari Hakkinen, Ville Pihlajaniemi, Markku Saloheimo, Johanna Buchert, Tiina Nakari-Setala
  • Publication number: 20140045238
    Abstract: The present invention relates to a method for producing terpenes in fungi, wherein a terpene biosynthetic gene cluster having terpene biosynthetic genes and regulatory regions operably linked to said genes is activated. The invention relates also to a terpene biosynthetic gene cluster and regulatory regions of such terpene biosynthetic gene cluster usable is production of terpenes, use of regulator for regulating the terpene production and use of Aspergillus nidulans FGSC A4 for producing terpenes. The method of invention provides higher yields of enriched terpene product without essential amount of side-products.
    Type: Application
    Filed: November 14, 2011
    Publication date: February 13, 2014
    Applicant: TEKNOLOGIAN TUTKIMUSKESKUS VTT
    Inventors: Kirsi Bromann, Tiina Nakari-Setala, Laura Ruohonen, Mervi Toivari, Merja Penttila
  • Patent number: 8546115
    Abstract: The present invention relates to polyesterases having cutinase and/or suberinase activity obtainable from Coprinus and Trichoderma. The invention further relates to a method for producing the polyesterases, and to polynucleotides, vectors and host cells used therein. The enzymes are useful in hydrolysing cutin, suberin and other polyesters for example in treating agricultural or food raw materials, or wood raw materials, pulp and paper products and waste, and in modifying polyester fibers, or in laundry and dish applications.
    Type: Grant
    Filed: July 8, 2008
    Date of Patent: October 1, 2013
    Assignee: Valtion Teknillinen Tutkimuskeskus
    Inventors: Johanna Buchert, Tiina Nakari-Setälä, Pasi Halonen, Hanna Kontkanen, Ann Westerholm-Parvinen, Marjaana Rättö
  • Publication number: 20100209985
    Abstract: The present invention relates to polyesterases having cutinase and/or suberinase activity obtainable from Coprinus and Trichoderma. The invention further relates to a method for producing the polyesterases, and to polynucleotides, vectors and host cells used therein. The enzymes are useful in hydrolysing cutin, suberin and other polyesters for example in treating agricultural or food raw materials, or wood raw materials, pulp and paper products and waste, and in modifying polyester fibers, or in laundry and dish applications.
    Type: Application
    Filed: July 8, 2007
    Publication date: August 19, 2010
    Applicant: Valtion Teknillinen Tutkimuskeskus
    Inventors: Johanna Buchert, Tiina Nakari-Setälä, Pasi Halonen, Hanna Kontkanen, Ann Westerholm-Parvinen, Marjaana Rättö
  • Publication number: 20090221039
    Abstract: The invention relates to fusion proteins including at least a swollenin and at least a plant cell-wall degrading enzyme, the swollenin, and plant cell-wall degrading enzyme, being recombinant proteins corresponding to native proteins in fungi, or mutated forms thereof. The invention also relates to the use of fusion proteins as defined above, for carrying out processes of plant cell-wall degradation in the frame of the preparation, from plants or vegetal by-products, of compounds of interest located in plant cell-wall, or in the frame of the bleaching of pulp and paper, or for biofuel production, or food industries.
    Type: Application
    Filed: April 2, 2007
    Publication date: September 3, 2009
    Applicants: Institut Francias Du Petrole, VTT Technical Research Centre of Finland, Institute National De La Recherche Agronomique, Universite De Provence
    Inventors: Eric Record, Anthony Levasseur, Markku Soloheimo, David Navarro, Martina Andgerg-Blomster, Frederic Monot, Tiina Nakari-Setala, Marcel Asther
  • Patent number: 7338779
    Abstract: This invention relates to a method for decreasing the foam formation during cultivation of a microorganism and to a method for producing an enhanced amount of a product of interest. The method comprises that the microorganism is modified in such a way that the microorganism does not produce an essential amount of at least one of the proteins, polypeptides or peptides associated with foam formation during cultivation of the unmodified microorganism. In particular the method comprises that the microorganism is modified not to produce an essential amount of amphipathic or hydrophobic proteins, polypeptides or peptides.
    Type: Grant
    Filed: August 21, 2000
    Date of Patent: March 4, 2008
    Assignee: Valtion Teknillinen Tutkimuskeskus
    Inventors: Tiina Nakari-Setälä, Merja Penttilä, Michael Bailey, Maija Tenkanen
  • Patent number: 7335492
    Abstract: The present invention relates to isolation and purification of protein in aqueous two-phase systems (ATPS). Specifically, the invention provides processes for partitioning of proteins of interest in ATPS by fusing said proteins to targeting proteins which have the ability of carrying said protein into one of the phases.
    Type: Grant
    Filed: October 19, 2005
    Date of Patent: February 26, 2008
    Assignee: Valtion Teknillinen Tutkimuskeskus
    Inventors: Merja Penttilä, Tiina Nakari-Setälä, Richard Fagerström, Klaus Selber, Maria-Regina Kula, Markus Linder, Folke Tjerneld
  • Patent number: 7060669
    Abstract: The present invention relates to isolation and purification of proteins in aqueous two-phase systems (ATPS). Specifically the invention provides processes for partitioning of proteins of interest in ATPS by fusing said proteins to targeting proteins which have the ability of carrying said protein into one of the phases.
    Type: Grant
    Filed: March 24, 2000
    Date of Patent: June 13, 2006
    Assignee: Valtion Teknillinen Tutkimuskeskus
    Inventors: Merja Penttilä, Tiina Nakari-Setälä, Richard Fagerström, Klaus Selber, Maria-Regina Kula, Markus Linder, Folke Tjerneld
  • Patent number: 7041464
    Abstract: The invention relates to a method for determining a gushing factor for a beverage, in which method the quantity of hydrophobin is determined from the raw material of the beverage and/or from the beverage. The hydrophobin determination is performed immunologically using an immunological reaction between a hydrophobin antigen and an antibody.
    Type: Grant
    Filed: August 18, 2004
    Date of Patent: May 9, 2006
    Assignee: Panimolaboratorio-Bryggerilaboratorium
    Inventors: Auli Haikara, Tuija Kleemola, Tiina Nakari-Setälä, Merja Penttilä
  • Publication number: 20060084164
    Abstract: The present invention relates to isolation and purification of protein in aqueous two-phase systems (ATPS). Specifically, the invention provides processes for partitioning of proteins of interest in ATPS by fusing said proteins to targeting proteins which have the ability of carrying said protein into one of the phases.
    Type: Application
    Filed: October 19, 2005
    Publication date: April 20, 2006
    Inventors: Merja Penttila, Tiina Nakari-Setala, Richard Fagerstrom, Klaus Selber, Maria-Regina Kula, Markus Linder, Folke Tjerneld
  • Publication number: 20050014204
    Abstract: The invention relates to a method for determining a gushing factor for a beverage, in which method the quantity of hydrophobin is determined from the raw material of the beverage and/or from the beverage. The hydrophobin determination is performed immunologically using an immunological reaction between a hydrophobin antigen and an antibody.
    Type: Application
    Filed: August 18, 2004
    Publication date: January 20, 2005
    Inventors: Auli Haikara, Tuija Sarlin, Tiina Nakari-Setala, Merja Penttila
  • Publication number: 20030148400
    Abstract: The invention relates to a method for determining a gushing factor for a beverage, in which method the quantity of hydrophobin is determined from the raw material of the beverage and/or from the beverage. The hydrophobin determination is performed immunologically using an immunological reaction between a hydrophobin antigen and an antibody.
    Type: Application
    Filed: December 4, 2002
    Publication date: August 7, 2003
    Inventors: Auli Haikara, Tuija Sarlin, Tiina Nakari-Setala, Merja Penttila