Patents by Inventor Tilanthi Jayawardena

Tilanthi Jayawardena has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Direct reprogramming of cells to cardiac myocyte fate
    Patent number: 11534464
    Abstract: A method for promoting conversion of cells into cardiomyocytic tissue is carried out by contacting fibrotic tissue (e.g., scar tissue) with a microRNA oligonucleotide or combination of microRNA oligonucleotides. The methods lead to direct reprogramming of fibroblasts to cardiomyocytes or cardiomyoblasts.
    Type: Grant
    Filed: June 29, 2020
    Date of Patent: December 27, 2022
    Assignee: Duke University
    Inventors: Victor J. Dzau, Maria Mirotsou, Tilanthi Jayawardena
  • DIRECT REPROGRAMMING OF CELLS TO CARDIAC MYOCYTE FATE
    Publication number: 20200345786
    Abstract: A method for promoting conversion of cells into cardiomyocytic tissue is carried out by contacting fibrotic tissue (e.g., scar tissue) with a microRNA oligonucleotide or combination of microRNA oligonucleotides. The methods lead to direct reprogramming of fibroblasts to cardiomyocytes or cardiomyoblasts.
    Type: Application
    Filed: June 29, 2020
    Publication date: November 5, 2020
    Inventors: Victor J. Dzau, Maria Mirotsou, Tilanthi Jayawardena
  • Direct reprogramming of cells to cardiac myocyte fate
    Patent number: 10695378
    Abstract: A method for promoting conversion of cells into cardiomyocytic tissue is carried out by contacting fibrotic tissue (e.g., scar tissue) with a microRNA oligonucleotide or combination of microRNA oligonucleotides. The methods lead to direct reprogramming of fibroblasts to cardiomyocytes or cardiomyoblasts.
    Type: Grant
    Filed: June 4, 2018
    Date of Patent: June 30, 2020
    Assignee: Duke University
    Inventors: Victor J. Dzau, Maria Mirotsou, Tilanthi Jayawardena
  • Direct Reprogramming of Cells to Cardiac Myocyte Fate
    Publication number: 20180344776
    Abstract: A method for promoting conversion of cells into cardiomyocytic tissue is carried out by contacting fibrotic tissue (e.g., scar tissue) with a microRNA oligonucleotide or combination of microRNA oligonucleotides. The methods lead to direct reprogramming of fibroblasts to cardiomyocytes or cardiomyoblasts.
    Type: Application
    Filed: June 4, 2018
    Publication date: December 6, 2018
    Inventors: Victor J. Dzau, Maria Mirotsou, Tilanthi Jayawardena
  • Direct reprogramming of cells to cardiac myocyte fate
    Patent number: 9987309
    Abstract: A method for promoting conversion of cells into cardiomyocytic tissue is carried out by contacting fibrotic tissue (e.g., scar tissue) with a microRNA oligonucleotide or combination of microRNA oligonucleotides. The methods lead to direct reprogramming of fibroblasts to cardiomyocytes or cardiomyoblasts.
    Type: Grant
    Filed: July 8, 2011
    Date of Patent: June 5, 2018
    Assignee: DUKE UNIVERSITY
    Inventors: Victor J. Dzau, Maria Mirotsou, Tilanthi Jayawardena
  • Direct Reprogramming of Cells to Cardiac Myocyte Fate
    Publication number: 20140011281
    Abstract: A method for promoting conversion of cells into cardiomyocytic tissue is carried out by contacting fibrotic tissue (e.g., scar tissue) with a microRNA oligonucleotide or combination of microRNA oligonucleotides. The methods lead to direct reprogramming of fibroblasts to cardiomyocytes or cardiomyoblasts.
    Type: Application
    Filed: July 8, 2011
    Publication date: January 9, 2014
    Applicant: DUKE UNIVERSITY
    Inventors: Victor J. Dzau, Maria Mirotsou, Tilanthi Jayawardena