Patents by Inventor Till Tiso

Till Tiso has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Extracellular production of designer hydroxyalkanoyloxy alkanoic acids with recombinant bacteria
    Patent number: 10907180
    Abstract: The present invention relates to a host cell comprising an rhlA gene or an ortholog thereof that is capable of producing hydroxyalkanoyloxy alkanoic acid (HAA) and achieving an HAA concentration of more than 1 g L?1 when cultured. The invention further relates to methods of producing such a host cell and to the use of said host cell for producing HAA. The present invention also relates to methods of producing HAA using said host cell, HAA compositions produced by these methods, as well as methods of producing fatty acid compositions, fatty alcohol compositions, or hydrocarbon compositions comprising producing HAA using said host cell, and fatty acid compositions, fatty alcohol compositions, or hydrocarbon compositions produced by said methods.
    Type: Grant
    Filed: July 6, 2016
    Date of Patent: February 2, 2021
    Assignee: Rheinisch-Westfaelische Technische Hochshule Aachen (RWTH)
    Inventors: Lars M. Blank, Till Tiso, Andrea Germer
  • EXTRACELLULAR PRODUCTION OF DESIGNER HYDROXYALKANOYLOXY ALKANOIC ACIDS WITH RECOMBINANT BACTERIA
    Publication number: 20180112241
    Abstract: The present invention relates to a host cell comprising an rhlA gene or an ortholog thereof that is capable of producing hydroxyalkanoyloxy alkanoic acid (HAA) and achieving an HAA concentration of more than 1 g L?1 when cultured. The invention further relates to methods of producing such a host cell and to the use of said host cell for producing HAA. The present invention also relates to methods of producing HAA using said host cell, HAA compositions produced by these methods, as well as methods of producing fatty acid compositions, fatty alcohol compositions, or hydrocarbon compositions comprising producing HAA using said host cell, and fatty acid compositions, fatty alcohol compositions, or hydrocarbon compositions produced by said methods.
    Type: Application
    Filed: July 6, 2016
    Publication date: April 26, 2018
    Inventors: Lars Blank, Till Tiso, Andrea M. Germer
  • Means and methods for rhamnolipid production
    Patent number: 9854799
    Abstract: Provided is a host cell comprising a rhlA gene or an ortholog thereof, under the control of a heterologous promoter and a rhlB gene or an ortholog thereof, under the control of a heterologous promoter. The host cell is capable of achieving a carbon yield of more than 0.18 Cmol rhamnolipid/Cmol substrate. Provided is also a method of producing rhamnolipids, employing such a host cell.
    Type: Grant
    Filed: September 21, 2012
    Date of Patent: January 2, 2018
    Assignee: Amlika Mercantile Private Limited
    Inventors: Lars Blank, Frank Rosenau, Susanne Wilhelm, Andreas Wittgens, Till Tiso
  • MEANS AND METHODS FOR RHAMNOLIPID PRODUCTION
    Publication number: 20140235561
    Abstract: Provided is a host cell comprising a rhlA gene or an ortholog thereof, under the control of a heterologous promoter and a rhlB gene or an ortholog thereof, under the control of a heterologous promoter. The host cell is capable of achieving a carbon yield of more than 0.18 Cmol rhamnolipid/Cmol substrate. Provided is also a method of producing rhamnolipids, employing such a host cell.
    Type: Application
    Filed: September 21, 2012
    Publication date: August 21, 2014
    Inventors: Lars Blank, Frank Rosenau, Susanne Wilhelm, Andreas Wittgens, Till Tiso