Patents by Inventor Tilla S. Worgall

Tilla S. Worgall has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aptamer methods and compositions
    Patent number: 11034952
    Abstract: Methods of selecting an aptamer that specifically binds to a target molecule complexed with a derivatization agent. Also disclosed are specific aptamers and methods of use thereof.
    Type: Grant
    Filed: December 17, 2018
    Date of Patent: June 15, 2021
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Milan N. Stojanovic, Tilla S. Worgall, Kyungae Yang
  • APTAMER METHODS AND COMPOSITIONS
    Publication number: 20190185845
    Abstract: Methods of selecting an aptamer that specifically binds to a target molecule complexed with a derivatization agent. Also disclosed are specific aptamers and methods of use thereof.
    Type: Application
    Filed: December 17, 2018
    Publication date: June 20, 2019
    Inventors: Milan N. Stojanovic, Tilla S. Worgall, Kyungae Yang
  • Method of isolating aptamers for minimal residual disease detection
    Patent number: 10294471
    Abstract: A method for selecting and isolating aptamers that target M-Ig proteins with a microdevice including at least a first selection chamber is provided. The method includes preparing a first sample of M-Ig proteins from a serum; placing the M-Ig proteins in the first selection chamber; introducing a first group of oligomers including at least an M-Ig targeting oligomer into the first selection chamber, whereby the M-Ig targeting oligomer binds to the first sample of M-Ig proteins. The method further includes removing unbound oligomers of the first sample from the first selection chamber to isolate the M-Ig targeting oligomer.
    Type: Grant
    Filed: January 24, 2017
    Date of Patent: May 21, 2019
    Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    Inventors: Qiao Lin, Milan N. Stojanovic, Timothy R. Olsen, Tilla S. Worgall
  • Methods to decrease susceptibility to asthmatic bronchoconstriction
    Patent number: 10159678
    Abstract: Methods and compositions are described for reducing airway reactivity and the susceptibility to asthmatic bronchoconstriction that involve increasing sphingolipid content in airways and lungs of a mammalian subject.
    Type: Grant
    Filed: May 16, 2013
    Date of Patent: December 25, 2018
    Assignees: Cornell University, Columbia University
    Inventors: Stefan Worgall, Tilla S. Worgall
  • Aptamer methods and compositions
    Patent number: 10155940
    Abstract: Methods of selecting an aptamer that specifically binds to a target molecule complexed with a derivatization agent. Also disclosed are specific aptamers and methods of use thereof.
    Type: Grant
    Filed: September 15, 2015
    Date of Patent: December 18, 2018
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Milan N. Stojanovic, Tilla S. Worgall, Kyungae Yang
  • APTAMER METHODS AND COMPOSITIONS
    Publication number: 20160076021
    Abstract: Methods of selecting an aptamer that specifically binds to a target molecule complexed with a derivatization agent. Also disclosed are specific aptamers and methods of use thereof.
    Type: Application
    Filed: September 15, 2015
    Publication date: March 17, 2016
    Applicant: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    Inventors: Milan N. Stojanovic, Tilla S. Worgall, Kyung-Ae Yang
  • METHODS TO DECREASE SUSCEPTIBILITY TO ASTHMATIC BRONCHOCONSTRICTION
    Publication number: 20150139915
    Abstract: Methods and compositions are described for reducing airway reactivity and the susceptibility to asthmatic bronchoconstriction that involve increasing sphingolipid content in airways and lungs of a mammalian subject.
    Type: Application
    Filed: May 16, 2013
    Publication date: May 21, 2015
    Inventors: Stefan Worgall, Tilla S. Worgall