Abstract: Systems and methods for improved interferometric imaging are presented. One embodiment is a partial field frequency-domain interferometric imaging system in which a light beam is scanned in two directions across a sample and the light scattered from the object is collected using a spatially resolved detector. The light beam could illuminate a spot, a line or a two-dimensional area on the sample. Additional embodiments with applicability to partial field as well as other types of interferometric systems are also presented.

Abstract: The system, method and device includes an optical coherence tomography (OCT) system switchable between single scan mode or multi-scan mode. This is achieved by use of multiple beam splitters to produce multiple OCT beams, but the system still uses a single light source, a single sample arm, and single reference arm to achieve a compact, more cost effective, system. Additionally presented is a spectral domain OCT system with a spectrometer having multiple grating, each providing a different depth and/or resolution imaging capability.

Abstract: An OCT system is constructed on a micro optical bench or semiconductor optical bench. The present OCT system may use free space optics and avoid the use of fiber optics.

Abstract: The present invention relates to a system for acquiring and visualizing OCT signals, comprising an OCT system and a display means designed for the time-resolved display of image data. The system further comprises a control unit configured to drive the OCT system to acquire a time-resolved OCT signal of a selected field of view of the sample and to determine a time-resolved OCT image on the basis of the acquired time-resolved OCT signal and a specifiable virtual viewing direction and to display the time-resolved OCT image on the display means. The present invention also relates to a corresponding method for acquiring and visualizing OCT signals.

Abstract: A system and method for multimodal image acquisition and image visualization, including a surgical-microscopic system with an optical unit and an image sensor and designed for acquiring a time-resolved image signal of a selected field of view of a sample. The system includes an OCT system, which is designed to acquire a time-resolved OCT signal of the selected field of view, a display means designed for the time-resolved display of image data and a control unit. The control unit is configured to ascertain video image data corresponding to the acquired image signal and to present them on the display means, to ascertain a time-resolved OCT image, corresponding at least to a portion of the presented video image data, on the basis of the acquired OCT signal, and to present the OCT image on the display means at the position of the portion.

Abstract: Systems and methods for improved interferometric imaging are presented. One embodiment is a partial field frequency-domain interferometric imaging system in which a light beam is scanned in two directions across a sample and the light scattered from the object is collected using a spatially resolved detector. The light beam could illuminate a spot, a line or a two-dimensional area on the sample. Additional embodiments with applicability to partial field as well as other types of interferometric systems are also presented.

Abstract: An apparatus for recording and displaying a three-dimensional OCT video includes an OCT system and a data processing unit configured to combine OCT volumes recorded sequentially in time to form a combined OCT volume, to generate display data which facilitate the display of the combined OCT volume, to register a current OCT volume of the OCT volumes, to combine the registered current OCT volume with the previous combined OCT volume to generate an updated combined OCT volume, to carry out a check for combining the registered current OCT volume with the previous combined OCT volume and in respect of which volume regions of the current OCT volume have changed in comparison with the corresponding volume regions of the previous combined OCT volume, and only to combine those volume regions of the current OCT volume that have not changed with the corresponding volume regions of the previous combined OCT volume.

Abstract: An apparatus for recording and displaying a three-dimensional OCT video includes an OCT system and a data processing unit configured to combine OCT volumes recorded sequentially in time to form a combined OCT volume, to generate display data which facilitate the display of the combined OCT volume, to register a current OCT volume of the OCT volumes, to combine the registered current OCT volume with the previous combined OCT volume to generate an updated combined OCT volume, to carry out a check for combining the registered current OCT volume with the previous combined OCT volume and in respect of which volume regions of the current OCT volume have changed in comparison with the corresponding volume regions of the previous combined OCT volume, and only to combine those volume regions of the current OCT volume that have not changed with the corresponding volume regions of the previous combined OCT volume.

Abstract: An OCT system for generating images of an anterior or posterior segment of an eye is described. The system includes a light source, a controller, optics, a detector, and a processor. The light source generates a beam of light and is capable of operating in a posterior or an anterior segment imaging mode. In the posterior segment imaging mode, light source outputs light with a first spectral bandwidth of less than 120 nm and including wavelengths between about 1060 to 1070 nm. In the anterior segment imaging mode the light source outputs light with a second spectral bandwidth that is larger than 120 nm. The controller enables switching between the posterior or anterior segment imaging mode.

Abstract: Systems and methods for improved interferometric imaging are presented. One embodiment is a partial field frequency-domain interferometric imaging system in which a light beam is scanned in two directions across a sample and the light scattered from the object is collected using a spatially resolved detector. The light beam could illuminate a spot, a line or a two-dimensional area on the sample. Additional embodiments with applicability to partial field as well as other types of interferometric systems are also presented.

Abstract: Systems and methods for improved interferometric imaging are presented. One embodiment is a partial field frequency-domain interferometric imaging system in which a light beam is scanned in two directions across a sample and the light scattered from the object is collected using a spatially resolved detector. The light beam could illuminate a spot, a line or a two-dimensional area on the sample. Additional embodiments with applicability to partial field as well as other types of interferometric systems are also presented.

Abstract: Various systems and methods for sequential angle illumination to achieve ultra-high resolution optical coherence tomography (OCT) images. One example OCT system includes a light source, a beam divider, sample arm optics, a detector, and a processor. The light source generates a light beam to illuminate the sample. The beam divider separates the light beam into reference and sample arms. The sample arm optics sequentially illuminates a location in the sample with the light beam from different angles. The detector receives light returned from the reference arm and the sample illuminated at each angle and generates signals. The processor combines the signals to generate an image, which has a transverse resolution that is higher than the transverse resolution achieved from the signal generated from a single angle.

Abstract: Various balanced detection systems which reduce alignment requirements of free space optics based balanced detection configurations are discussed. One example system includes a light source, a beam divider, sample optics, return optics, and a processor. The light source generates a light beam. The beam divider separates the light beam into reference and sample arms. The sample optics deliver the light beam in the sample arm to a light scattering object to be imaged. The return optics direct light to a balanced detection system, which has a balanced detection beam divider for combining light scattered from the object and light from the reference arm and directing the combined light into two detection channels and two detectors for collecting the combined light in the two detection channels and generating signals in response thereto. The processor processes the signals and generates image data of the object based on the processed signals.

Abstract: An OCT system for generating images of an anterior or posterior segment of an eye is described. The system includes a light source, a controller, optics, a detector, and a processor. The light source generates a beam of light and is capable of operating in a posterior or an anterior segment imaging mode. In the posterior segment imaging mode, the light source outputs light with a spectral bandwidth equal or narrower than the width of the 1060 nm water absorption window. In the anterior segment imaging mode, the light source outputs light with a spectral bandwidth larger than the width of the 1060 nm water absorption window. The controller enables switching between the posterior or anterior segment imaging mode. The optics scan the light over a set of transverse locations across the eye. The detector measures returning light and generates output signals for use by the processor to generate images.

Abstract: Techniques are introduced to improve the ability of OCT to determine more accurately the nature of the flow of fluids in the eye, including faster measurements of the flow and a method to reduce geometric uncertainties due to eye movements.

Abstract: Various systems and methods for sequential angle illumination to achieve ultra-high resolution optical coherence tomography (OCT) images. One example OCT system includes a light source, a beam divider, sample arm optics, a detector, and a processor. The light source generates a light beam to illuminate the sample. The beam divider separates the light beam into reference and sample arms. The sample arm optics sequentially illuminates a location in the sample with the light beam from different angles. The detector receives light returned from the reference arm and the sample illuminated at each angle and generates signals. The processor combines the signals to generate an image, which has a transverse resolution that is higher than the transverse resolution achieved from the signal generated from a single angle.

Abstract: Various balanced detection systems which reduce alignment requirements of free space optics based balanced detection configurations are discussed. One example system includes a light source, a beam divider, sample optics, return optics, and a processor. The light source generates a light beam. The beam divider separates the light beam into reference and sample arms. The sample optics deliver the light beam in the sample arm to a light scattering object to be imaged. The return optics direct light to a balanced detection system, which has a balanced detection beam divider for combining light scattered from the object and light from the reference arm and directing the combined light into two detection channels and two detectors for collecting the combined light in the two detection channels and generating signals in response thereto. The processor processes the signals and generates image data of the object based on the processed signals.

Abstract: Improved line-field imaging systems incorporating planar waveguides are presented. In one embodiment the optics of the system are configured such that a line of light on the light scattering object is imaged to the planar waveguide in at least one dimension. Embodiments where the waveguide incorporates a beamsplitter of an interferometer, where the beam divider and waveguide are referenced to one or more common surfaces, and wherein the source and waveguide are optically coupled, are also considered. In another embodiment, the planar waveguide is in contact or close proximity to the light scattering object.

Abstract: Techniques are introduced to improve the ability of OCT to determine more accurately the nature of the flow of fluids in the eye, including faster measurements of the flow and a method to reduce geometric uncertainties due to eye movements.

Abstract: Techniques are introduced to improve the ability of OCT to determine more accurately the nature of the flow of fluids in the eye, including faster measurements of the flow and a method to reduce geometric uncertainties due to eye movements.