Patents by Inventor Tilmann KÜNZL

Tilmann KÜNZL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cellular transport system for transferring a sulfonic acid construct carrying a cargo into the cytoplasm of a cell
    Patent number: 11661398
    Abstract: The present invention relates to a cellular transport system for bringing a sulfonic acid construct which carries a cargo into a cell and releasing the cargo in the cell's cytoplasm, the cellular transport system comprising: (i) a sulfonate transporter located in the cytoplasm membrane of the cell wherein said sulfonate transporter is capable of transporting said sulfonic acid construct across the cytoplasm membrane into the cytoplasm; (ii) a ?-glutamyl transferase (GGT; EC 2.3.2.2) which is modified to be located in the cytoplasm of the cell, wherein said ?-glutamyl transferase is capable of hydrolyzing said sulfonic acid construct so as to release the cargo. Moreover, the present invention relates to the use of a cellular transport system for bringing a sulfonic acid construct which contains a cargo into a cell and releasing the cargo in the cell's cytoplasm. Further, the present invention relates to a ?-glutamyl transferase for hydrolyzing a sulfonic acid construct which contains a cargo.
    Type: Grant
    Filed: October 2, 2018
    Date of Patent: May 30, 2023
    Assignee: Scientist of Fortune, S.A.
    Inventors: Tilmann Künzl, Sven Panke, Philippe Marlière
  • CELLULAR TRANSPORT SYSTEM FOR TRANSFERRING A SULFONIC ACID CONSTRUCT CARRYING A CARGO INTO THE CYTOPLASM OF A CELL
    Publication number: 20210009513
    Abstract: The present invention relates to a cellular transport system for bringing a sulfonic acid construct which carries a cargo into a cell and releasing the cargo in the cell's cytoplasm, the cellular transport system comprising: (i) a sulfonate transporter located in the cytoplasm membrane of the cell wherein said sulfonate transporter is capable of transporting said sulfonic acid construct across the cytoplasm membrane into the cytoplasm; (ii) a ?-glutamyl transferase (GGT; EC 2.3.2.2) which is modified to be located in the cytoplasm of the cell, wherein said ?-glutamyl transferase is capable of hydrolyzing said sulfonic acid construct so as to release the cargo. Moreover, the present invention relates to the use of a cellular transport system for bringing a sulfonic acid construct which contains a cargo into a cell and releasing the cargo in the cell's cytoplasm. Further, the present invention relates to a ?-glutamyl transferase for hydrolyzing a sulfonic acid construct which contains a cargo.
    Type: Application
    Filed: October 2, 2018
    Publication date: January 14, 2021
    Inventors: Tilmann KÜNZL, Sven PANKE, Philippe MARLIERE