Abstract: A multi-part medical marker (1) comprising a marker core consisting of at least two corresponding parts (2a, 2b) and comprising a detectable surface, wherein the surface is substantially formed from a detectable coating (4) which is applied to the surface (3) of the parts (2a, 2b) of the marker core (2). An apparatus for producing a medical marker comprising a marker core (?2) and a detectable surface, comprises: —a first feeding device (16) for providing the marker core (2); —an application device (17) for applying a detectable layer to the surface (3) of the marker core (2); and—a transport device (18) for transporting the marker core (2) within the apparatus.

Abstract: A multi-part medical marker (1) comprising a marker core consisting of at least two corresponding parts (2a, 2b) and comprising a detectable surface, wherein the surface is substantially formed from a detectable coating (4) which is applied to the surface (3) of the parts (2a, 2b) of the marker core (2).

Abstract: The present invention relates to a method for producing a multi-part medical marker (1) comprising a marker core (2) consisting of at least two corresponding parts (2a, 2b) and comprising a detectable surface, said method comprising the following steps: —providing the parts (2a, 2b) of the marker core (2); —applying a detectable layer (4) to the surface (3) of the parts (2a, 2b) of the marker core (2); and —joining the parts (2a, 2b) of the marker core (2) together to form a marker (1). The present invention also relates to a multi-part medical marker comprising a marker core consisting of at least two corresponding parts (2a, 2b) and comprising a detectable surface, wherein the surface is substantially formed from a detectable coating (4) which is applied to the surface (3) of the parts (2a, 2b) of the marker core (2).

Abstract: In one embodiment, a method of filling a container with a liquid drug from a drug reservoir may include: a) connecting a container and a drug reservoir with a cannula such that the drug reservoir and the container fluidically communicate with each other via the cannula, while being hermetically sealed; b) reducing a first volume contained within the container to displace a gaseous medium from the first volume of the container via the cannula into a second volume contained within the drug reservoir; c) increasing the first volume of the container to displace the liquid drug from the second volume of the drug reservoir into the first volume of the container to fill the container; and d) disconnecting the container and the drug reservoir. Before performing action d), action b) and action c) can be successively performed more than once to stepwise increase an amount of liquid drug displaced.

Abstract: In one embodiment, a method of filling a container with a liquid drug from a drug reservoir may include: a) connecting a container and a drug reservoir with a cannula such that the drug reservoir and the container fluidically communicate with each other via the cannula, while being hermetically sealed; b) reducing a first volume contained within the container to displace a gaseous medium from the first volume of the container via the cannula into a second volume contained within the drug reservoir; c) increasing the first volume of the container to displace the liquid drug from the second volume of the drug reservoir into the first volume of the container to fill the container; and d) disconnecting the container and the drug reservoir. Before performing action d), action b) and action c) can be successively performed more than once to stepwise increase an amount of liquid drug displaced.

Abstract: The present invention relates to a method for producing a multi-part medical marker (1) comprising a marker core (2) consisting of at least two corresponding parts (2a, 2b) and comprising a detectable surface, said method comprising the following steps:—providing the parts (2a, 2b) of the marker core (2);—applying a detectable layer (4) to the surface (3) of the parts (2a, 2b) of the marker core (2); and—joining the parts (2a, 2b) of the marker core (2) together to form a marker (1). The present invention also relates to a multi-part medical marker comprising a marker core consisting of at least two corresponding parts (2a, 2b) and comprising a detectable surface, wherein the surface is substantially formed from a detectable coating (4) which is applied to the surface (3) of the parts (2a, 2b) of the marker core (2).

Abstract: The sealing cover (1) comprises a planar support (3), on which a number of sealing elements (4) are arranged, each of which is provided for the sealing of a sample container (2). The planar support (3) and the sealing elements (4) are produced from different materials in the same injection molding tool (21) by means of two-component injection molding. The planar support (3) is detachably connected to the sealing elements (4) by means of adhesion. The planar support (3) and the sealing elements (4) are preferably made from related plastics.

Abstract: The planar optical structure forms an evanescent-field measuring platform. A body is made from the thermoplastic plastic with a three-dimensionally structured surface, wherein molding is performed directly from a master made of glass coated with metal oxide, without deposition of further coatings on a surface of the master. The planar optical structure forming an evanescent-field measuring platform has a first essentially optically transparent, waveguiding layer (a) with a refractive index n1 and a second essentially optical transparent layer (b) with refractive index n2, where n1>n2, in a case of an embodiment of a planar optical film waveguide, or a metal layer (a?) and a second layer (b), in a case of an embodiment for generating a surface plasmon resonance, wherein the second layer (b) includes a material from a group of cyclo-olefin polymers and cyclo-olefin copolymers.

Abstract: In one embodiment, a method of filling a container with a liquid drug from a drug reservoir may include: a) connecting a container and a drug reservoir with a cannula such that the drug reservoir and the container fluidically communicate with each other via the cannula, while being hermetically sealed; b) reducing a first volume contained within the container to displace a gaseous medium from the first volume of the container via the cannula into a second volume contained within the drug reservoir; c) increasing the first volume of the container to displace the liquid drug from the second volume of the drug reservoir into the first volume of the container to fill the container; and d) disconnecting the container and the drug reservoir. Before performing action d), action b) and action c) can be successively performed more than once to stepwise increase an amount of liquid drug displaced.

Abstract: The present invention relates to a method for manufacture a body from a thermoplastic plastic with a three-dimensionally structured surface, wherein molding is performed directly from a master made of glass coated with metal oxide, without deposition of further coatings on a surface of the master. The invention also relates to bodies manufactured with this method from a thermoplastic featuring a three-dimensionally structured surface, as well as to planar optical structures likewise manufactured with this method for generating evanescent-field measuring platforms and to a use thereof.

Abstract: The present invention relates to a method for manufacture a body from a thermoplastic plastic with a three-dimensionally structured surface, wherein molding is performed directly from a master made of glass coated with metal oxide, without deposition of further coatings on a surface of the master. The invention also relates to bodies manufactured with this method from a thermoplastic featuring a three-dimensionally structured surface, as well as to planar optical structures likewise manufactured with this method for generating evanescent-field measuring platforms and to a use thereof.

Abstract: A system of flow-through cells is obtained by assembling a body with a base plate. The body has a first spring element and a first stop, disposed on opposite end sections of the body, at least one second spring element and a corresponding second stop, disposed on opposite faces of the body, and at least one support element and at least one retaining element, which are adapted for the exact positioning of the body in the receiving openings of a support in three directions.

Abstract: A system of flow-through cells is obtained by assembling a body with a base plate. The body has a first spring element and a first stop, disposed on opposite end sections of the body, at least one second spring element and a corresponding second stop, disposed on opposite faces of the body, and at least one support element and at least one retaining element, which are adapted for the exact positioning of the body in the receiving openings of a support in three directions.

Abstract: The present invention is directed generally to devices and methods with the purpose of interfacing microfluidic devices with dispensing and fluid handling systems. Specifically, the present invention consists in the design of the inlets of a microfluidic device in such a way that multiple units can be loaded as a single compact device, with a unitary interface format which is compatible with existing industry standards.

Abstract: An integrally built, linear array of cuvettes is made of a plastic material. This array comprises a plurality of cuvettes arranged along a straight line in an array, each cuvette in the array having the same shape and dimensions, and neighboring cuvettes being connected to each other by a single web. Each of the single webs has a curved shape. The symmetry axis (Y-Y) of every cuvette forming part of said array of cuvettes lies substantially in one and the same plane (A-A) which is a symmetry plane of said cuvette array. The upper part of at least one intermediate cuvette which is located between a first cuvette located at one end of the cuvette array and a second cuvette located at the opposite end of the cuvette array is connected by a first single web to the upper part of a neighboring cuvette lying on one side of said intermediate cuvette and is connected by a second single web to the upper part of a neighboring cuvette lying on the opposite side of said intermediate cuvette.

Abstract: An integrally built, linear array of cuvettes is made of a plastic material. Every cuvette of the array has the same shape and dimensions. Neighboring cuvettes are connected to each other by a single web. Each of the single webs has a curved shape and each cuvette has means forming integral part thereof and serving for accurately positioning the cuvette into an opening of a cuvette holder and means for removably connecting the cuvette to the cuvette holder. Each cuvette has an upper chamber and a lower chamber having a common symmetry axis passing through the centers of both chambers. Each of the upper and lower chambers has a substantially cylindrical shape. The cross-section of the upper chamber at the central part thereof is larger than the cross-section of the lower chamber. The lower chamber has an open lower end. The upper chamber has an open top end and an annular bottom wall having a central circular opening which connects the upper chamber with the lower chamber.

Abstract: The sealing cover (1) comprises a planar support (3), on which a number of sealing elements (4) are arranged, each of which is provided for the sealing of a sample container (2). The planar support (3) and the sealing elements (4) are produced from different materials in the same injection moulding tool (21) by means of two-component injection moulding. The planar support (3) is detachably connected to the sealing elements (4) by means of adhesion. The planar support (3) and the sealing elements (4) are preferably made from related plastics.

Abstract: The present invention relates to a method for the manufacture a body from a thermoplastic plastic with a three-dimensionally structured surface, wherein the molding is carried out directly from a master made of glass coated with metal oxide, without the deposition of further coatings on the surface of said master. The invention also relates to bodies manufactured with this method from a thermoplastic featuring a three-dimensionally structured surface as well as to planar optical structures likewise manufactured with this method for generating evanescent-field measuring platforms and to the use thereof.

Abstract: The invention relates to a system of flow-through cells that is obtained by assembling a body (11) with a base plate. The body (11) comprises the following elements which are adapted for the exact positioning of the body in the receiving openings of a support in three directions (Y, Y, Z direction): (a) a first spring element and a first stop, disposed on opposite end sections of the body (11), (b) at least one second spring element and a corresponding second stop, disposed on opposite faces of the body (11), and (c) at least one support element and at least one retaining element.

Abstract: An integrally built, linear array of cuvettes is made of a plastic material. Every cuvette of the array has the same shape and dimensions. Neighboring cuvettes are connected to each other by a single web. Each of the single webs has a curved shape and each cuvette has means forming integral part thereof and serving for accurately positioning the cuvette into an opening of a cuvette holder and means for removably connecting the cuvette to the cuvette holder. Each cuvette has an upper chamber and a lower chamber having a common symmetry axis passing through the centers of both chambers. Each of the upper and lower chambers has a substantially cylindrical shape. The cross-section of the upper chamber at the central part thereof is larger than the cross-section of the lower chamber. The lower chamber has an open lower end. The upper chamber has an open top end and an annular bottom wall having a central circular opening which connects the upper chamber with the lower chamber.